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| 1 | Methyloxime-substituted aminopyrrolidine: A new surrogate for 7-basic group of quinolone 显示文摘 | Hong C Y Kim Y K Lee Y H | 1998 | Bioorg Med Chem Lett1998，，8： | 2 |
| 2 | Structure determination of metabolites isolated from urine and bile after administration of AY4166, a novel D-phenylalanine-derivative hypoglycemic agent 显示文摘 | Takesada H Matsuda K Ohtake R | 1996 | Bioorg Med Chem1996，4，10： | 2 |
| 3 | Triarylimidazole inhibitors of IL- 1 biosynthesis 显示文摘 | Gallageher TG Fier-Thompson SM Garigipati etal | 1995 | Bioorg Med Chem Lett1995，5，8： | 2 |
| 4 | Modelisation, synthesis and anti-HIV activities of N, N, N',N'', N-pentakistetraazamacrocycles salts derivatives显示文摘 | Trabaud C Dessolin J Vileghe P | 1997 | Bioorg Med Chem Lett1997，7，： | 2 |
| 5 | Potent non- steroidal progesterone receptor agonists: synthesis and SAR study of 6-aryl benzoxazines 显示文摘 | ZHANG P TEREFENKO EA FENSOME A | 2002 | Bioorg Med Chem Lett2002，12，5： | 1 |
| 6 | 显示文摘 | Schneider R Sehmitt F | 2005 | Bioorg Med Chem2005，13，： | 1 |
| 7 | Synthesis and Preliminary Biological Evaluation of the ^99Tc^m Labeled Nitrobenzoimidazole and Nitrotriazole as Tumor Hypoxia Markers 显示文摘 | Zhang Y Chu T Gao X | 2006 | Bioorg Med Chem Let2006，16，： | 1 |
| 8 | Aplysamine-1 and related analogs as histamine H3 receptor antagonists显示文摘 | SWANSON D M WILSON S J BOGGS J D | 2006 | Bioorg Med Chem Lett2006，16，4： | 1 |
| 9 | Discovery and structure-activity relationships of 4-aminoquinazoline derivatives,a novel class of opioid receptor like-1 (ORL1) antagonists显示文摘 | Okano M Mito J Maruyama Y | 2009 | Bioorg Med ChemLett2009，17，： | 1 |
| 10 | Antioxidant activity and xanthine oxidase inhibition activity of reductic acid: ascorbic acid analogue显示文摘 | Mashino T Takigawa Y Saito N | 2000 | Bioorg Med Chem Lett2000，10，24： | 1 |
| 11 | Synthesis and biological evaluation of new derivatives of emodin 显示文摘 | Lars Teich Katja Scarlett Daub Vera Krugel | 2004 | Bioorg Med Chem2004，12，22： | 1 |
| 12 | Synthesis and biological evaluation of 4-morpholino-2- phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors 显示文摘 | Hayakawa M Kaizawa H Moritomo H | 2006 | Bioorg Med Chem2006，14，20： | 1 |
| 13 | Cyclin-dependent kinase 4 inhibitors as a treatment for cancer, part 1 : identification and optimisation of substituted 4,6-bis anilino pyrimidines 显示文摘 | Beattie J F Breault G A Green S | 2003 | Bioorg Med Chem Lett2003，13，18： | 1 |
| 14 | Synthesis and cytotoxicity of water soluble quaternary salt derivatives of camptothecin显示文摘 | Zu Yuangang Li Qingyong Fu Yujie | 2004 | Bioorg Med Chem Lett2004，14，15： | 1 |
| 15 | The design,sy-nthesis,and anti-tumor mechanism study of N-phosphoryl amino acid modified resveratrol analogues显示文摘 | LIU H C DONG A GAO C | 2008 | Bioorg Med Chem2008，16，10： | 1 |
| 16 | Thalassiolins A-C: new marine-derived inhibitors of HIV eDNA integrase显示文摘 | Rowley D C Hansen M S T Rhodes D | 2002 | Bioorg Med Chen2002，10，： | 1 |
| 17 | Amidine derived inhibitors of acidsensing ion channel-3(ASIC3)显示文摘 | Knduk S D Chang R K Wai J M | 2009 | Bioorg Mad Chem Lett2009，19，15： | 1 |
| 18 | Synthesis and evaluation of 2' ,4',6'-trihydroxychalcones as a new class of tyrosinase inhibitors 显示文摘 | Jun N Hong G Jun K | 2007 | Bioorg Med Chem2007，15，6： | 1 |
| 19 | Structural requirements of flavonoids for nitric oxide pro- duction inhibitory activity and mechanism of action 显示文摘 | Matsuda H | 2003 | Bioorg Med Chem2003，9，： | 1 |
| 20 | Haemolytic ac tivity,cytotoxicity and membrane cell permeabilization of semi synthetic and natural lupane-and oleanane-type saponins显示文摘 | Gauthier C Legault J Girard-Lalancette IC | 2009 | Bioorg med chem2009，17，5： | 1 |
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