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| 1 | Depression in patients with irritable bowel syndrome in Jos,Nigeria显示文摘AIM: To study the brain-gut interaction and the effect of behavioral or psychiatric conditions on irritable bowel syndrome (IBS) in an African population. METHODS: IBS was diagnosed using the Rome Ⅱ diagnostic criteria. The entry of each patient was confirmed following detailed explanations of the questions. Four hundred and eighteen patients were studied. Subjects satisfying the Rome Ⅱ criteria for IBS were physically examined and stool microscopy was done to identify the presence of “alarm factors”. Depression was diagnosed using the symptom-check list adapted from the Research Diagnostic Criteria (DSM-Ⅳ) of the American Psychiatric Association. RESULTS: Seventy-five (56.8%) of the 132 IBS patients were depressed whereas only 54 (20.1%) of the 268 non-IBS patients were depressed. There was a significant relationship between IBS and depression (χ2 = 54.29, Odds ratio = 5.21, 56.8 ± 8.4 vs 20.1 ± 5.2, P = 0.001). Even though constipation predominant IBS patients were more likely to be depressed, no significant relationship was found between the subtype of IBS and depression (χ2 = 0.02, OR = 0.95, P = 0.68). CONCLUSION: IBS is significantly associated with major depression but not gender and bowel subtypes of the patients. Patients with IBS need to be evaluated for depression due to the highly significant relationship between the two conditions. | Nimzing G Ladep Taiwo J Obindo Moses D Audu Edith N Okeke Abraham O Malu | 2006 | World Journal of Gastroenterology2006，12，48： | 22 |
| 2 | Potential relevance of pig gut content transplantation for production and research显示文摘It is becoming increasingly evident that the gastrointestinal microbiota has a significant impact on the overall health and production of the pig.This has led to intensified research on the composition of the gastrointestinal microbiota,factors affecting it,and the impact of the microbiota on health,growth performance,and more recently,behavior of the host.Swine production research has been heavily focused on assessing the effects of feed additives and dietary modifications to alter or take advantage of select characteristics of gastrointestinal microbes to improve health and feed conversion efficiency.Research on faecal microbiota transplantation(FMT) as a possible tool to improve outcomes in pigs through manipulation of the gastrointestinal microbiome is very recent and limited data is available.Results on FMT in humans demonstrating the transfer of phenotypic traits from donors to recipients and the high efficacy of FMT to treat Clostridium difficile infections in humans,together with data from pigs relating GI-tract microbiota composition with growth performance has likely played an important role in the interest towards this strategy in pig production.However,several factors can influence the impact of FMT on the recipient,and these need to be identified and optimized before this tool can be applied to pig production.There are obvious inherent biosecurity and regulatory issues in this strategy,since the donor's microbiome can never be completely screened for all possible non-desirable microorganisms.However,considering the success observed in humans,it seems worth investigating this strategy for certain applications in pig production.Further,FMT research may lead to the identification of specific bacterial group(s) essential for a particular outcome,resulting in the development of banks of clones which can be used as targeted therapeutics,rather than the broader approach applied in FMT.This review examines the factors associated with the use of FMT,and its potential application to swine production,and includes research on using the pig as model for human medical purposes. | Nuria Canibe Mark O’Dea Sam Abraham | 2019 | Journal of Animal Science and Biotechnology2019，10，3： | 6 |
| 3 | Incidence, predictors at admission, and impact of worsening renal function among patients hospitalized with heart failure显示文摘 | Daniel E. Forman Javed Butler Yongfei Wang William T. Abraham Christopher M. O’Connor Stephen S. Gottlieb Evan Loh Barry M. Massie Michael W. Rich Lynne Warner Stevenson James B. Young Harlan M. Krumholz | 2004 | Journal of the American College of Cardiology2004，，1： | 2 |
| 4 | Characteristics, Treatments, and Outcomes of Patients With Preserved Systolic Function Hospitalized for Heart Failure显示文摘 | Gregg C. Fonarow Wendy Gattis Stough William T. Abraham Nancy M. Albert Mihai Gheorghiade Barry H. Greenberg Christopher M. O'Connor Jie Lena Sun Clyde W. Yancy James B. Young | 2007 | Journal of the American College of Cardiology2007，，8： | 2 |
| 5 | Characteristics, Treatments, and Outcomes of Patients With Preserved Systolic Function Hospitalized for Heart Failure显示文摘 | Gregg C. Fonarow Wendy Gattis Stough William T. Abraham Nancy M. Albert Mihai Gheorghiade Barry H. Greenberg Christopher M. O’Connor Jie Lena Sun Clyde W. Yancy James B. Young | 2007 | Journal of the American College of Cardiology2007，，8： | 2 |
| 6 | Absence of CNTNAP2 leads to epilepsy,neuronal migration abnormalities,and core autism-related deficits显示文摘 | Pe(n)agarikano O Abrahams BS Herman EI | | 0，，01： | 1 |
| 7 | Effects of Cardiac Resynchronization on Disease Progression in Patients With Left Ventricular Systolic Dysfunction, an Indication for an Implantable Cardioverter-Defibrillator, and Mildly Symptomatic Chronic Heart Failure显示文摘 | William T. Abraham James B. Young Angel R. León Stuart Adler Alan J. Bank Shelley A. Hall Randy Lieberman L Bing Liem John B. O’Connell John S. Schroeder Kevin R. Wheelan | 2004 | Circulation2004，，18： | 1 |
| 8 | Management of primary hypot- hyroidism: statement by the British Thyroid Association Executive Com- mittee 显示文摘 | Okosieme O Gilbert J Abraham P | 2016 | Clin Endocrinol (Oxf)2016，84，6： | 1 |
| 9 | Role of the molecular absorbent recycling system(MARS)in the treatment of patients with acute exacerbation of chronic liver failure显示文摘 | Sorkine P Abraham R B Szold O | 2001 | Crit Care Med2001，29，7： | 1 |
| 10 | Post-exposure prophylaxis for blood borne viral infections in healthcare workers显示文摘 | Varghese G M Abraham O C Mathai D | 2003 | Postgrad Med J2003，79，932： | 1 |
| 11 | Chemical analysis of chicorysamples显示文摘 | Ramalakshmi K Rao P G P Abraham K O | 1994 | Indian Coffee1994，58，3： | 1 |
| 12 | Predictors of mortality after dis-charge in patients hospitalized with heart failure:an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure(OPTIMIZE-HF)显示文摘 | O’Connor CM Abraham WT Albert NM | 2008 | Am Heart J2008，156，： | 1 |
| 13 | Influence of non-aqueous solvents on the electrochemistry of oxygen in the recharge-able lithium air battery显示文摘 | LAOIRE C O MUKERJEE S ABRAHAM K M | 2010 | J Phys Chem C2010，114，19： | 1 |
| 14 | Predictors of multi-organ dysfunction in heatstroke 显示文摘 | G M Varghese G John K Thomas O C Abraham D Mathai | 2005 | Emerg Med J2005，22，： | 1 |
| 15 | Post-exposure Prophylaxis for bloodborne viral infections in healthcare workers显示文摘 | Varghese G Abraham O Mathai D | 2003 | Postgraduate Medical Journal2003，79，932： | 1 |
| 16 | Role of the molecular adsorbent recycling system (MARS) in the treatment of patients with acute exacerbation of chronic liver failure 显示文摘 | Sorkine P Abraham RB Szold O | 2001 | Crit Care Med2001，29，： | 1 |
| 17 | Primary cardiac lipoblastoma 显示文摘 | Dishop MK O'Connor WN Abraham S | 2001 | Pediatr Dev Pathol2001，4，3： | 1 |
| 18 | Relative molar volume and limiting solubility of He^3 in superfluid He^4 显示文摘 | Abraham B M Brandt O G Eckstein Y | 1969 | Physical Review1969，188，1： | 1 |
| 19 | Elucidating themechanism of oxygen reduction for lithium-air battery applications 显示文摘 | LAOIRE C O MUKERJEE S ABRAHAM K M | 2009 | JPhys Chem C2009，113，20： | 1 |
| 20 | Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF) 显示文摘 | O'CONNOR C M ABRAHAM W T ALBERT N M | 2008 | Am Heart J2008，156，4： | 1 |
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