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	题名	作者	年代	出处	被引量
1	Brain changes in diabetes mellitus patients withgastrointestinal symptoms显示文摘Diabetes mellitus is a common disease and its prevalence is increasing worldwide. In various studies up to 30%-70% of patients present dysfunction and complications related to the gut. To date several clinical studies have demonstrated that autonomic nervous system neuropathy and generalized neuropathy of the central nervous system(CNS) may play a major role. This systematic review provides an overview of the neurodegenerative changes that occur as a consequence of diabetes with a focus on the CNS changes and gastrointestinal(GI) dysfunction. Animal models where diabetes was induced experimentally support that the disease induces changes in CNS. Recent investigations with electroencephalography and functional brain imaging in patients with diabetes confirm these structural and functional brain changes. Encephalographic studies demonstrated that altered insular processing of sensory stimuli seems to be a key player in symptom generation. In fact one study indicated that the more GI symptoms the patients experienced, the deeper the insular electrical source was located. The electroencephalography was often used in combination with quantitative sensory testingmainly showing hyposensitivity to stimulation of GI organs. Imaging studies on patients with diabetes and GI symptoms mainly showed microstructural changes,especially in brain areas involved in visceral sensory processing. As the electrophysiological and imaging changes were associated with GI and autonomic symptoms they may represent a future therapeutic target for treating diabetics either pharmacologically or with neuromodulation.	Anne M Drewes Eirik Søfteland Georg Dimcevski Adam D Farmer Christina Brock Jens B Frøkjær Klaus Krogh Asbjørn M Drewes	2016	World Journal of Diabetes2016，7，2：	4
2	Circulating MicroRNA Is a Biomarker of Pediatric Crohn Disease显示文摘	Adam M Zahm Meena Thayu Nicholas J Hand Amber Horner Mary B Leonard Joshua R Friedman	2011	Journal of Pediatric Gastroenterology and Nutrition2011，，1：	3
3	Performance of an adaptive multichannel combiner for long range underwater communications显示文摘	Sharif B S Neasham J A Hinton O R Adams A E	1996	IEE Electronics letters1996，32，3：	1
4	Efficacy and safety of fluconazole prophylaxis for fungal infections after marrow transplantation--aprospective,randomized,double-blind study显示文摘	Slavin MA Osborne B Adams R	1995	J Infect Dis1995，171，6：	1
5	Molecular dynamics simulations of consolidation processes during fabrication of nanophase palladium显示文摘	Liu C L Adams J B Siegal R W	1994	Nanostructured Materials1994，4，4：	1
6	Intraocular pressure elevation after subtenon injection of triamcinolone acetonide during uveitis显示文摘	Bui Quoc E Bodaghi B Adam R	2002	J Fr Ophtalmol2002，25，10：	1
7	A Computationally Efficient Doppler Compensation Sys tern for Under Water Acoustic Communications显示文摘	Sharif B S Neasham J Hinton O R Adams A E	2000	IEEE Journal of Oceanic Engineering2000，25，1：	1
8	Occurrence of glutathione in bacteria显示文摘	Fahey R C Brown W C Adams W B	1978	Journal of Bacteriology1978，133，3：	1
9	Powerful CEOs and Their Impact on Corporate Performance显示文摘	ADAMS R B ALMEIDA H FERREIRA D	2005	Review of Financial Studies2005，18，4：	1
10	Towards a pan-European consensus on the treatment of patients with colorectal liver metastases 显示文摘	Van Cutsem E Nordlinger B Adam R	2006	Eur J Cancer2006，42，14：	1
11	Process configurations adapted to membrane bioreactors for enhanced biological phosphorus and nit rogen removal 显示文摘	L ESJ FAN B GNIRSS R ADAM C	2002	Desalination2002，149，：	1
12	A vibration technique for non - destructive assessing the integrity of structures显示文摘	Cawley P Pye C J Stone B J	1978	Journal of Mechanical Engineering Science1978，20，：	1
13	A novel Pd/MgAlOx catalyst for NOX storage-reduction显示文摘	SILLETTI B A ADAMS R T SIGMON S M NIKOLOPOULOS A SPIVEY J J LAMB H H	2006	Catal Today2006，114，1：	1
14	Further aspects of design by P-Delta method显示文摘	Wood B R Beaulieu D Adams P F	1976	Journal of the Structural Division ASCE1976，102，3：	1
15	One Hundred Questions of Importance to the Conservation of Global Biological Diversity 显示文摘	SUTHERLAND W J ADAMS W M ARONSON R B	2009	Conservation Biology2009，23，3：	1
16	Characterisation and expression of a PP1serine/threonine protein phosphatase(PfPP1) from the malaria parasite, Plasmodiumfalciparum:demonstration of its essential role using RNA interference 显示文摘	Kumar R Adams B Oldenburg A	2002	Malar J2002，1，1：	1
17	Novel high capacitance materials:BaTiO3:La and CaCu3Ti4O12显示文摘	West A R Adams T B Morrison F D	2004	J Euro Cera Soci2004，24，：	1
18	Stable haptic interaction with virtual environments显示文摘	Hannaford B	1999	IEEE Transactions on Robotics and Automation1999，15，3：	1
19	Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes 显示文摘	Riechmann J L Heard J Martin G Reuber L Jiang C Keddie J Adam L Pineda O Ratcliffe O J Samaha R R Creelman R Pilgrim M Broun P Zhang J Z Ghandehari D Sherman B K Yu G	2000	Science2000，290，：	1
20	A theory of friendly boards显示文摘	Adams R B Ferreira D	2007	Joumal of Finance2007，，62：	1

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