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| 1 | Relationship between serum cytokine levels and histopathological changes of liver in patients with hepatitis B显示文摘AIM: To investigate whether there was a relationship between the liver functions and fibrosis scores of hepatitis B patients and their TNF-α, IFN-γ, IL-4, and TGF-β1 serum levels based on the studies of liver biopsies. METHODS: Thirty patients with chronic hepatitis B (CHB)receiving no treatment and 30 healthy individuals with negative hepatitis serology and normal values of liver biochemistry were studied. After serum samples of the patients were collected, liver needle biopsy was performed on each patient. Cytokine levels were studied by ELISA.The biopsy materials were scored based on Knodell's histological activity index.RESULTS: In comparison of cytokine levels between CHB patients and control group, TNF-α, IL-4, and TGF-β1 levels of the patients were higher in CHB patients than in the controls, while IFN-γ level was lower in the patients than in the controls. There were significant differences between the groups in TNF-α, IL-4, TGF-β1, and IFN-γ (P<0.005,0.03, 0.002, 0.0001, respectively). There was a negativecorrelation between TGF-β1 and IL-4 and IFN-γ (P<0.05),TNF-α and the other cytokines and IFN-γ and IL-4 were not correlated (P>0.05). TGF-β1 was correlated with fibrosis (P<0.05). Liver necroinflammatory activity and fibrosis and TNF-α, IL-4, and IFN-γ were not correlated (P>0.05).CONCLUSION: In the course of HBV infection and its chronic progress, cytokines play an important role. IL-4and IFN-γ are effective in the chronic progression, whileTGF-β1 is effective in the development of fibrosis. Serum cytokine levels may be effective tools in the estimation of chronic progression and fibrosis development. | Nusret Akpolat Seyfettin Yahsi Ahmet Godekmerdan Kutbettin Demirbag Mehmet Yalniz | 2005 | World Journal of Gastroenterology2005，11，21： | 46 |
| 2 | Endorectal ultrasonography versus phased-array magnetic resonance imaging for preoperative staging of rectal cancer显示文摘AIM: To compare the diagnostic accuracy of pelvic phased-array magnetic resonance imaging (MRI) and endorectal ultrasonography (ERUS) in the preoperative staging of rectal carcinoma. METHODS: Thirty-four patients (15 males, 19 females) with ages ranging between 29 and 75 who have biopsy proven rectal tumor underwent both MRI and ERUS examinations before surgery. All patients were evaluated to determine the diagnostic accuracy of depth of transmural tumor invasion and lymph node metastases. Imaging results were correlated with histopathological findings regarded as the gold standard and both modalities were compared in terms of predicting preoperative local staging of rectal carcinoma. RESULTS: The pathological T stage of the tumors was: pT1 in 1 patient, pT2 in 9 patients, pT3 in 21 patients and pT4 in 3 patients. The pathological N stage of the tumors was: pN0 in 19 patients, pN1 in 9 patients and pN2 in 6 patients. The accuracy of T staging for MRI was 89.70% (27 out of 34). The sensitivity was 79.41% and the specificity was 93.14%. The accuracy of T staging for ERUS was 85.29% (24 out of 34). The sensitivity was 70.59% and the specificity was 90.20%. Detection of lymph node metastases usingphased-array MRI gave an accuracy of 74.50% (21 out of 34). The sensitivity and specificity was found to be 61.76% and 80.88%, respectively. By using ERUS in the detection of lymph node metastases, an accuracy of 76.47% (18 out of 34) was obtained. The sensitivity and specificity were found to be 52.94% and 84.31%, respectively. CONCLUSION: ERUS and phased-array MRI are complementary methods in the accurate preoperative staging of rectal cancer. In conclusion, we can state that phased-array MRI was observed to be slightly superior in determining the depth of transmural invasion (T stage) and has same value in detecting lymph node metastases (N stage) as compared to ERUS. | Ahmet Mesrur Halefoglu Sadik Yildirim Omer Avlanmis Damlanur Sakiz Adil Baykan | 2008 | World Journal of Gastroenterology2008，14，22： | 35 |
| 3 | Gastrointestinal bezoars: A retrospective analysis of 34 cases显示文摘AIM: Bezoars (BZ) are the most common foreign bodies of gastrointestinal tract. Clinical manifestations vary depending on the location of BZ from no symptoms to acute abdominal syndrome. When located in small bowel, they frequently cause small bowel obstruction (SBO). We aimed to present our experience by reviewing literature.METHODS: Thirty-four patients with gastrointestinal BZ were presented. The data were collected from hospital records and analyzed retrospectively. Morbidity and mortality rates were statistically analyzed between the subgroups according to SBO and endoscopic or surgical treatment modalities.RESULTS: The 34 patients had phytobezoars (PBZ). Two patients with mental retardation and trichotillomania had trichobezoars (TBZ). More than half of them (55.88%) had previous gastric surgery. Also most of them had small bowel bezoars resulting in obstruction. Surgical and endoscopic morbidity rates were 32.14% and 14.28% respectively.The total morbidity rate of this study was 29.41%. Four patients in surgically treated group died. There was no death in endoscopically treated group. The total and surgical mortality rates were 11.76% and 14.28% respectively. The differences in morbidity and mortality rates between the subgroups were not statistically significant.CONCLUSION: BZ are commonly seen in stomach and small intestine. SBO is the most common complication.When uncomplicated, endoscopic or surgical removal can be applied easily. | Kenan Erzurumlu Zafer Malazgirt Ahmet Bektas Adem Dervisoglu Cafer Polat Gokhan Senyurek Ibrahim Yetim Kayhan Ozkan | 2005 | World Journal of Gastroenterology2005，11，12： | 33 |
| 4 | Susceptibility weighted imaging: Clinical applications and future directions显示文摘Susceptibility weighted imaging(SWI) is a recently developed magnetic resonance imaging(MRI) technique that is increasingly being used to narrow the differential diagnosis of many neurologic disorders. It exploits the magnetic susceptibility differences of various compounds including deoxygenated blood, blood products, iron and calcium, thus enabling a new source of contrast in MR. In this review, we illustrate its basic clinical applications in neuroimaging. SWI is based on a fully velocity-compensated, high-resolution, three dimensional gradientecho sequence using magnitude and phase images either separately or in combination with each other, in order to characterize brain tissue. SWI is particularly useful in the setting of trauma and acute neurologic presentations suggestive of stroke, but can also characterize occult low-flow vascular malformations, cerebral microbleeds, intracranial calcifications, neurodegenerative diseases and brain tumors. Furthermore, advanced MRI post-processing technique with quantitative susceptibility mapping, enables detailed anatomical differentiation based on quantification of brain iron from SWI raw data. | Ahmet Mesrur Halefoglu David Mark Yousem | 2018 | World Journal of Radiology2018，10，4： | 32 |
| 5 | Magnetic resonance cholangiopancreatography: A useful tool in the evaluation of pancreatic and biliary disorders显示文摘Magnetic resonance cholangiopancreatography (MRCP) is being used with increasing frequency as a noninvasive alternative to diagnostic retrograde cholangiopancreatography (ERCP). The aim of this pictorial review is to demonstrate the usefulness of MRCP in the evaluation of pancreatic and biliary system disorders. Because the recently developed techniques allows improved spatial resolution and permits imaging of the entire pancreaticobiliary tract during a single breath hold, MRCP is of proven utility in a variety of pancreatic and biliary disorders. It uses MR imaging to visualize fluid in the biliary and pancreatic ducts as high signal intensity on T2 weighted sequences and is the newest modality for pancreatic and biliary duct imaging. Herein, we present the clinical applications of MRCP in a variety of pancreaticobiliary system disorders and conclude that it is an important diagnostic tool in terms of imaging of the pancreaticobiliary ductal system. | Ahmet Mesrur Halefoglu | 2007 | World Journal of Gastroenterology2007，13，18： | 26 |
| 6 | 野生毛花猕猴桃种质资源主要数量性状变异分析及评价指标探讨显示文摘【目的】更好地对江西省境内野生毛花猕猴桃(Actinidia eriantha Benth.)资源进行评价。【方法】对野生毛花猕猴桃118份资源果实的主要数量性状进行统计分析和分级。果实的主要数量性状包括单果质量、果形指数、干物质含量、维生素C、可溶性固形物(SSC)、可溶性糖及可滴定酸7项指标,根据K-S正态性检验及频率分布对数量性状进行分级。【结果】单果质量变异系数最大,为33.65%;可溶性固形物最小,为11.91%。经K-S正态性检验,大部分性状呈偏正态分布;根据分析结果,提出5级数量性状分级标准,每个等级提出2份不同区域种质作为参照。【结论】该研究可为我国毛花猕猴桃资源描述的规范化、标准化提供参考。 | 郎彬彬 朱博 谢敏 张文标 Umut Ahmet Seyrek 黄春辉 徐小彪 | 2016 | 果树学报2016，33，1： | 23 |
| 7 | Treatment options in patients with metastatic gastric cancer:Current status and future perspectives显示文摘Despite advances in the treatment of gastric cancer,it remains the world’s second highest cause of cancer death.As gastric cancer is often diagnosed at an advanced stage,systemic chemotherapy is the mainstay of treatment for these patients.However,no standard palliative chemotherapy regimen has been accepted for patients with metastatic gastric cancer.Palliative chemotherapy including fluoropyrimidine,platin compounds,docetaxel and epirubicin prolongs survival,and improves a high quality of life to a greater extent than best supportive care.The number of clinical investigations associated with targeted agents has recently increased.Agents targeting the epidermal growth factor receptor 1 and human epidermal growth factor receptor 2(HER2)have been widely tested.Trastuzumab was the first target drug developed,and pivotal phaseⅢtrials showed improved survival when trastuzumab was integrated into cisplatin/fluoropyrimidine-based chemotherapy in patients with metastatic gastric cancer.Trastuzumab in combination with chemotherapy was thus approved to be a new standard of care for patients with HER2-positive advanced esophagogastric adenocarcinoma.Thus,the evaluation of HER2 status in all patients with metastatic gastroesophageal adenocarcinoma should be considered.Other agents targeting vascular endothelial growth factor,mammalian target of rapamycin,and other biological pathways have also been investigated in clinical trials,but showed little impact on the survival of patients.In this review,systemic chemotherapy and targeted therapies for metastatic gastric cancer in the first-and second-line setting are summarized in the light of recent advances. | Ahmet Bilici | 2014 | World Journal of Gastroenterology2014，20，14： | 23 |
| 8 | 建设项目管理模式与中国建筑业的改革显示文摘本文探讨了中国建筑业的发展、改革及所遇到的问题。为了解决这些问题,深化中国建筑业的改革,需要变革建设项目的组织模式和建筑市场的项目采购方式。建设项目组织模式是成功进行项目管理的基石,也是业主和建设项目成功的关键因素。因为它确定了项目管理的总体框架、基本路径和项目的风险结构及项目各方的责任与义务。本文介绍了国际上流行的项目组织模式及其演变和发展;不同项目组织模式的特征及其相互联系;分析了项目采购方式在深化我国建筑市场改革和加速建筑业与国际接轨的作用和意义;提出了深化中国建筑业改革应采取的对策,以缓解加入WTO对我国建筑业的压力。 | 阎长俊 Kemal Ahmet | 2002 | 中国软科学2002，，4： | 16 |
| 9 | Progress in surgical and nonsurgical approaches for hepatocellular carcinoma treatment显示文摘BACKGROUND:Hepatocellular carcinoma(HCC) is a complex and heterogeneous malignancy,frequently occurs in the setting of a chronically diseased organ,with multiple confounding factors making its management challenging.HCC represents one of the leading causes of cancer-related mortality globally with a rising trend of incidence in some of the developed countries,which indicates the need for better surgical and nonsurgical management strategies.DATA SOURCES:Pub Med database was searched for relevant articles in English on the issue of HCC management.RESULTS:Surgical resection represents a potentially curative option for appropriate candidates with tumors detected at earlier stages and with well-preserved liver function.The long-term outcome of surgery is impaired by a high rate of recurrence.Surgical approaches are being challenged by local ablative therapies such as radiofrequency ablation and microwave ablation in selected patients.Liver transplantation offers potential cure for HCC and also correction of underlying liver disease,and minimizes the risk of recurrence,but is reserved for patients within a set of criteria proposed for a prudent allocation in the shortage of donor organs.Transcatheter locoregional therapies have become the palliative standard allowing local control for intermediate stage patients with noninvasive multinodular or large HCC who are beyond the potentially curative options.The significant survival benefit with the multikinase inhibitor sorafenib for advanced HCC has shifted the direction of research regarding systemic treatment toward molecular therapies targeting the disregulated pathways of hepatocarcinogenesis.Potential benefit is suggested from simultaneous or sequential multimodal therapies,and optimal combinations are being investigated.Despite the striking progress in preclinical studies of HCC immunotherapy and gene therapy,extensive clinical trials are required to achieve successful clinical applications of these innovative approaches.CONCLUSION:Treatment decisions have become increasingly complex for HCC with the availability of multiple surgical and nonsurgical therapeutic options and require a comprehensive,multidisciplinary approach. | Ender Gunes Yegin Erkan Oymac1 Emrah Karatay Ahmet Coker | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，3： | 14 |
| 10 | Expression of bcI-2 gene family during resection induced liver regeneration:Comparison between hepatectomized and sham groups显示文摘AIM:During liver regeneration cellular proliferation and apoptosis result in tissue remodeling to restore normal hepatic mass and structure.Main regulators of the apoptotic machinery are the Bcl-2 family proteins but their roles are not well defined throughout the liver regeneration.We aimed to analyze the expression levels of bcl-2 gene family members during resection induced liver regeneration.METHODS:We performed semi-quantitative RT-PCR to examine the expression level of bak, bax, bcl-2 and bcl-XL in 70% hepatectomized rat livers during the whole regeneration process and compared to that of the sham and normal groups.RESULTS:The expression of bak and baxwas decreased whereas that of bcl-2 and bcl-XL was increased in hepatectomized animals compared to normal liver at most time points.We also reported for the first time that sham group of animals had statistically significant higher expression of bak and bax than hepatectomized animals.In addition, the area under the curve (AUC) values of these genes was larger in sham groups than the hepatectomized groups.CONCLUSION: The expression changes of bak, bax, bcl-2 and bcl-XL genes are altered not only due to regeneration,but also due to effects of surgical operations. | Kamil Can Akcali Aydin Dalgic Ahmet Ucar Khemaeis Ben Haj Dilek Guvenc | 2004 | World Journal of Gastroenterology2004，10，2： | 13 |
| 11 | Biliary endoscopic sphincterotomy: Techniques and complications显示文摘Biliary endoscopic sphincterotomy(EST) refers to the cutting of the biliary sphincter and intraduodenal segment of the common bile duct following selective cannulation, using a high frequency current applied with a special knife, sphincterotome, inserted into the papilla. EST is either used solely for the treatment of diseases of the papilla of Vater, such as sphincter of Oddi dysfunction or to facilitate subsequent therapeutic biliary interventions, such as stone extraction, stenting, etc. It is a prerequisite for biliary interventions, thus every practitioner who performs endoscopic retrograde cholangiopancreatography needs to know different techniques and the clinical and anatomic parameters related to the efficacy and safety of the procedure. In this manuscript, we will review the indications, contraindications and techniques of biliary EST and the management of its complications. | Ayd?n Seref Kksal Ahmet Tarik Eminler Erkan Parlak | 2018 | World Journal of Clinical Cases2018，6，16： | 12 |
| 12 | BOT模式与建设项目采购方式的变革显示文摘项目采购方式(PPR)是成功进行项目管理的基石,对业主和建设项目的成功都是关键因素,它确定了项目管理的基本路径和总体框架。BOT是一种全新的PPR和公共项目私人融资方式,它鼓励私人部门营建基础设施项目或政府公共项目,并以此为基础提供公共服务。本文介绍了国际上流行的项目采购方式及其演变;分析了BOT模式产生的背景和发展趋势及我国实施BOT项目的必要性和可行性;提出了推行新的PPR应采取的对策,以深化我国建筑市场改革和加速我国建筑业与国际接轨,缓解加入WTO对我国建筑业的压力。 | 阎长俊 Kemal Ahmet | 2001 | 中国软科学2001，，11： | 12 |
| 13 | Effect of asymmetric rolling process on the microstructure,mechanical properties and texture of AZ31 magnesium alloys sheets produced by twin roll casting technique显示文摘Symmetric rolling(SR)and asymmetric rolling(ASR)processes were carried out on 6 mm thick AZ31 magnesium alloy sheets that were produced by twin roll casting(TRC)technique.Before rolling processes,sheets were heat treated in order to obtain a homogenized microstructure.In this study,for the ASR process the rolling speed ratio between upper roller and lower was selected as 1.25.Both SR and ASR processes were utilized with 40%reduction per passes using 2 pass schedule for a total reduction ratio of 0.67.Symmetric and asymmetric rolled sheets were characterized using optical microscopy(OM),scanning electron microscopy(SEM)and transmission electron microscopy(TEM)techniques.Texture measurements were performed by using X-ray diffraction(XRD)technique and mechanical properties were investigated by tensile tests and also hardness measurements. | Selda Ucuncuoglu Ahmet Ekerim Gizem Oktay Secgin Ozgur Duygulu | 2014 | Journal of Magnesium and Alloys2014，2，1： | 11 |
| 14 | Recurrent anterior shoulder instability: Review of the literature and current concepts显示文摘The purpose of this review article is to discuss the clinical spectrum of recurrent traumatic anterior shoulder instability with the current concepts and controversies at the scientific level. Because of increasing participation of people from any age group of the population in sports activities, health care professionals dealing with the care of trauma patients must have a thorough understanding of the anatomy, patho-physiology, risk factors, and management of anterior shoulder instability. The risk factors for recurrent shoulder dislocation are young age, participation in high demand contact sports activities, presence of Hill-Sachs or osseous Bankart lesion, previous history of ipsilateral traumatic dislocation, ipsilateral rotator cuff or deltoid muscle insufficiency, and underlying ligamentous laxity. Achieving the best result for any particular patient depends onthe procedure that allows observation of the joint surfaces, provides the anatomical repair, maintains range of motion, and also can be applied with low rates of complications and recurrence. Although various surgical techniques have been described, a consensus does not exist and thus, orthopedic surgeons should follow and try to improve the current evidence-based treatment modalities for the patients. | Hakan Sofu Sarper Gürsu Nizamettin Ko?kara Ali ?ner Ahmet Issιn Yalkιn ?amurcu | 2014 | World Journal of Clinical Cases2014，2，11： | 10 |
| 15 | Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer显示文摘AIM:To evaluate the levels of preoperative serum matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in gastric cancer.METHODS:One hundred gastric cancer patients who underwent gastrectomy were enrolled in this study.The serum concentrations of MMP-1 and TIMP-1 in these patients and in fifty healthy controls were determined using an enzyme-linked immunosorbent assay.RESULTS:Higher serum MMP-1 and TIMP-1 levels were observed in patients than in controls (P < 0.001).Serum MMP-1 and TIMP-1 levels were positively associated with morphological appearance,tumor size,depth of wall invasion,lymph node metastasis,liver metastasis,perineural invasion,and pathological stage.They were not significantly associated with age,gender,tumor location,or histological type.CONCLUSION:Increased MMP-1 and TIMP-1 were associated with gastric cancer.Although these markers are not good markers for diagnosis,these markers show in advanced gastric cancer. | Ozgur Kemik Ahu Sarbay Kemik Aziz Sümer Ahmet Cumhur Dulger Mine Adas Huseyin Begenik Ismail Hasirci Ozkan Yilmaz Sevim Purisa Erol Kisli Sefa Tuzun Cetin Kotan | 2011 | World Journal of Gastroenterology2011，17，16： | 10 |
| 16 | Clinical pregnancies and livebirths achieved by intracytoplasmic injection of round headed acrosomeless spermatozoa with and without oocyte activation in familial globozoospermia: case report显示文摘我们报导 intracytoplasmic 精子的成功的结果在有家庭 globozoospermia 的二个兄弟的注射(ICSI ) 治疗。在控制卵巢的亢奋的刺激和卵母细胞提取以后,检索了卵母细胞在 ICSI 和 33.3% 的授精率在第一个案例中被完成以前,机械地被激活。没有卵母细胞激活,第二对夫妇经历了 ICSI, 9.1% 授精率被获得。二个等级的转移我在第一对夫妇和夫妇的胚胎分级我在第二对夫妇的胚胎与健康实时出生导致了临床的怀孕。有 globozoospermia 的案例的主要问题是低授精率,这被结束,并且尽管 ICSI 和卵母细胞激活能增加这率,完成怀孕未必被需要。 | Enver K. Dirican Ahmet Isik KubilayVicdan Eran Sozen Zekiye Suludere | 2008 | Asian Journal of Andrology2008，10，2： | 9 |
| 17 | Circulating cancer stem cells:the importance to select显示文摘It has been demonstrated that even localized tumors without clinically apparent metastasis give rise to circulating tumor cells(CTCs).A growing number of technically diverse platforms are being developed for detecting/isolating CTCs in the circulating blood.Despite the technical challenges of isolating rare CTCs from blood,recent studies have already shown the predictive value of CTCs enumeration.Thus,it is becoming increasingly accepted that CTC numbers are linked to patients' outcome and may also be used to monitor treatment response and disease relapse,respectively.Further CTCs provide a non-invasive source for tumor material,'liquid biopsy',which is particularly important for patients,where no biopsy material can be obtained or where serial biopsies of the tumor,e.g.,following treatment,are practically impossible.On the other hand the molecular and biological characterization of CTCs has still remained at a rather experimental stage.Future studies are necessary to define CTC heterogeneity to establish the crucial role of circulating cancer stem cells for driving metastasis,which represent a distinct subpopulation of CTCs that bear metastasis-initiating capabilities based on their stemness properties and invasiveness and thus are critical for the patients' clinical outcome.As compared to non-tumorigenic/metastatic bulk CTCs,circulating cancer stem cells may not only be capable of evading from the primary tumor,but also escape from immune surveillance,survive in the circulating blood and subsequently form metastases in distant organs.Thus,circulating cancer stem cells represent a subset of exclusively tumorigenic cancer stem cells characterized by their invasive characteristics and are potential therapeutic targets for preventing disease progression.To date,only a few original reports and reviews have been published focusing on circulating cancer stem cells.This review discusses the potential importance of isolating and characterizing these circulating cancer stem cells,but also highlights current technological limitations. | Ming-Hsin Yang Ahmet Imrali Christopher Heeschen | 2015 | Chinese Journal of Cancer Research2015，27，5： | 9 |
| 18 | 回归再时效处理过程中AA7075铝合金的性能(英文)显示文摘采用回归法分别在180、240和320℃下热处理AA7075铝合金1、30、50、70、90和120 min。回归处理后,再在T6(120℃,24 h)热处理制度下对合金进行时效处理。通过V型冲击和硬度测试确定时效样品的力学性能,并通过测定电导率确定样品的物理性能。此外,利用光学显微镜和透射电镜表征合金的显微组织性能。结果表明,回归再时效的温度和时间对合金冲击韧性和硬度的影响与晶界的析出相有关。 | Gokhan OZER Ahmet KARAASLAN | 2017 | Transactions of Nonferrous Metals Society of China2017，27，11： | 9 |
| 19 | Palliation of malignant esophageal obstruction and fistulas with self expandable metallic stents显示文摘AIM: To evaluate the efficacy of self expandable metallic stents (SEMS) in patients with malignant esophageal obstruction and fistulas. METHODS: SEMS were implanted in the presence of fluoroscopic guidance in patients suffering from advanced and non-resectable esophageal, cardiac and invasive lung cancer between 2002 and 2009. All procedures were performed under conscious sedation. All patients had esophagus obstruction and/or fistula. In all patients who required reintervention, recurrence of dysphagia, hemorrhage, and fistula formation were indications for further endoscopy. Patients' files were scanned retrospectively and the obtained data were analyzed using SPSS 13.0 for Windows. The χ 2 test was used for categorical data and was analysis of variance for noncategorical data. Patients' long-term survival was assessed using the Kaplan-Meier method. RESULTS: Stents were successfully implanted in 90 patients using fluoroscopic guidance. Reasons for stent implantation in these patients were esophageal stricture (77/90, 85.5%), external pressure (8/90, 8.8%) and tracheo-esophageal fistula (5/90, 5.5%). Dysphagia scores (mean ± SD) were 3.37 ± 0.52 before and 0.90 ± 0.43 after stent implantation (P = 0.002). Intermittent, nonmassive hemorrhage due to the erosion caused by the distal end of the stent in the stomach occurred in only one patient who received implementation at cardioesophageal junction. Mean survival following stenting was 134.14 d (95% confidence interval: 94.06-174.21).CONCLUSION: SEMS placement is safe and effective in the palliation of dysphagia in selected patients with malignant esophageal strictures. | Ahmet Dobrucali Erkan Caglar | 2010 | World Journal of Gastroenterology2010，16，45： | 9 |
| 20 | Gallbladder function and dynamics of bile flow in asymptomatic gallstone disease显示文摘AIM:To investigate the effects of gallbladder stones on motor functions of the gallbladder and the dynamics of bile flow in asymptomatic gallstone disease.METHODS:Quantitative hepatobiliary scintigraphy was performed to detect the parameters of gallbladder motor function [gallbladder ejection fraction(GBEF),gallbladder visualization time(GBVT),gallbladder time to peak activity(GBTmax),gallbladder half emptying time(GBT1/2),and transit time of bile to duodenum(TTBD)] in 24 patients with asymptomatic cholelithiasis who were diagnosed incidentally during routine abdominal ultrasonographic examination and 20 healthy subjects with normal gallbladder.RESULTS:Even though there was no significant difference in the clinical and laboratory parameters between the patient and control groups,all parameters of gallbladder function except TTBD were found to differ significantly between the two groups.GBEF in the patient group was decreased(P=0.000) and GBVT,GBTmax,GBT1/2 in the patient group were longer(P=0.000,P=0.015,P=0.001,respectively).CONCLUSION:Our results showed that even if there were not any clinical and laboratory findings,gallbladder filling and emptying could be impaired in patients with gallstone disease. | Sevim Süreyya eri Feride Meltem zbek Celal eri Bahattin Baykal Hasan Erol Eroglu Zeynep Baykal Mustafa Yildiz Semahat Saglam Ahmet Yesildag | 2009 | World Journal of Gastroenterology2009，15，22： | 8 |
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