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| 1 | Evolution and advances in laparoscopic ventral and incisional hernia repair显示文摘Primary ventral hernias and ventral incisional hernias have been a challenge for surgeons throughout the ages. In the current era, incisional hernias have increased in prevalence due to the very high number of laparotomies performed in the 20 th century. Even though minimally invasive surgery and hernia repair have evolved rapidly, general surgeons have yet to develop the ideal, standardized method that adequately decreases common postoperative complications, such as wound failure, hernia recurrence and pain. The evolution of laparoscopy and ventral hernia repair will be reviewed, from the rectoscopy of the 4th century to the advent of laparoscopy, from suture repair to the evolution of mesh reinforcement. The nuances of minimally invasive ventral and incisional hernia repair will be summarized, from preoperative considerations to variations in intraoperative practice. New techniques have become increasingly popular, such as primary defect closure, retrorectus mesh placement, and concomitant component separation. The advent of robotics has made some of these repairs more feasible, but only time and well-designed clinical studies will tell if this will be a durable modality for ventral and incisional hernia repair. | Alan L Vorst Christodoulos Kaoutzanis Alfredo M Carbonell Michael G Franz | 2015 | World Journal of Gastrointestinal Surgery2015，7，11： | 10 |
| 2 | 抗炎介质表达缺陷参与中性粒细胞型支气管哮喘发病机制:半乳糖凝集素-3和白细胞介素-1RA/白细胞介素-1beta比例显著下降显示文摘支气管哮喘(哮喘)是具有异质性的气道炎症性疾病,其主要特点表现为气道高反应和可变的气流受限。在哮喘的发病机制中,过敏原诱导的TH2淋巴细胞激活以及IL-5介导的嗜酸粒细胞渗出起到重要的作用。近年来发现超过50%的哮喘患者气道的嗜酸粒细胞水平并不增高,并将这种亚型定义为非嗜酸粒细胞型哮喘。其中部分患者表现为气道中性粒细胞明显增高,称为中性粒细胞型哮喘。 | 高鹏 Peter G Gibson Katherine J Baines Ian A Yang John W Upham Paul N Reynolds Sandra Hodge Alan L James Christine Jenkins Matthew J Peters 张捷 Jodie L Simpson | 2016 | 中华结核和呼吸杂志2016，39，11： | 5 |
| 3 | Diagnostic accuracy of tests for Helicobacter pylori in an Alaska Native population显示文摘AIM:To evaluate the accuracy of two non-invasivetests in a population of Alaska Native persons. Highrates of Helico bacter pylori(H. pylori) infection,H. pylori treatment failure,and gastric cancer in this population necessitate documentation of infection status atmultiple time points over a patient's life.METHODS:In 280 patients undergoing endoscopy,H. pylori was diagnosed by culture,histology,rapidurease test,13C urea breath test(UBT) ,and immuno-globulin G antibodies to H. pylori in serum. The performances of 13C-UBT and antibody test were compared to a gold standard defined by a positive H. pylori testby culture or,in case of a negative culture result,bypositive histology and a positive rapid urease test.RESULTS:The sensitivity and specificity of the 13C-UBT were 93% and 88%,respectively,relative to thegold standard. The antibody test had an equivalents ensitivity of 93% with a reduced specificity of 68%.The false positive results for the antibody test were as-sociated with previous treatment for an H. pylori infection [relative risk(RR) = 2.8]. High levels of antibodiesto H. pylori were associated with chronic gastritis and male gender,while high scores in the 13C-UBT testwere associated with older age and with the H. pyloribacteria load on histological examination(RR = 4.4) .CONCLUSION:The 13C-UBT out performed the anti-body test for H. pylori and could be used when a non-invasive test is clinically necessary to document treatment out come or when monitoring for reinfection. | Dana L Bruden Michael G Bruce Karen M Miernyk Julie Morris Debby Hurlburt Thomas W Hennessy Helen Peters Frank Sacco Alan J Parkinson Brian J McMahon | 2011 | World Journal of Gastroenterology2011，17，42： | 3 |
| 4 | Mutations affecting starch synthase III in arabidopsis alter leaf starch structure and increase the rate of starch synthesisl显示文摘 | Zhang X L Alan M M Martha G | 2005 | Plant Physiology2005，138，： | 1 |
| 5 | Characterization of the myeloid-specific CD11b promoter显示文摘 | Heike L Alan G Daniel G | 1992 | Blood1992，79，4： | 1 |
| 6 | Dendritic cell expression of the Notch ligand jagged is not essential for Th2response induction in vivo显示文摘 | Alan G Salome L Emma S | 2008 | Eur J Immunol2008，38，： | 1 |
| 7 | The ICP as an ion source-origins,achievements and prospects显示文摘 | Alan L G | 1985 | Spectrochimica Acta Part B:Atomic Spectroscopy1985，40，1012： | 1 |
| 8 | Betalain,acid ascorbic,phenolic contents and antioxidant properties of purple,red,yellow and white cactus pears显示文摘 | SUMAYA M M T CRUZ J S MADRIGAL S E GARCíA P CARIO C J CRUZ C R VALADEZ V MARTINEZ C C L ALANíS G E | 2011 | International Journal of Molecular Sciences2011，12，10： | 1 |
| 9 | Micropower impulse radar:a Novel technology for rapid,real-time detection of pneumothorax显示文摘 | Phillip D L Tracey W Alan G | 2011 | Emergency Medicine International2011，，3： | 1 |
| 10 | Dendritic cell expression of the Notch ligand jagged2 is not essential for Th2 response induction in vivo 显示文摘 | Alan G Salome L Emma S | 2008 | Eur J Immunol2008，38，： | 1 |
| 11 | Comparison of oxygen consumption in freshwater mussels (Unionidae) from different habitats during declining dissolved oxygen concentration 显示文摘 | Chen L Y Alan G H Richard J N | 2001 | Hydrobiologia2001，450，3： | 1 |
| 12 | Overview of the lincoln laboratory ballistic missile defense program显示文摘 | William Z L Alan A G | 2002 | Lincoln Laboratory Journal2002，13，1： | 1 |
| 13 | Metabolites from an antarctic sponge-associated bacterium Pseudomonasae ruginosa 显示文摘 | Jayatilake G S Maureen P T Alan C L | 1996 | J Nat Prod1996，59，3： | 1 |
| 14 | Release of the antioxidants ascorbate and urate from a nitrergically-innervated smooth muscle 显示文摘 | Elliot L Alan G | 1997 | Br J Pharmacol1997，122，： | 1 |
| 15 | Micropower impulse radar: a novel technology for rapid,real-time detection of pneumothorax显示文摘 | Phillip D L Traeey W Alan G | 2011 | Eme- rgency Medicine International2011，3，： | 1 |
| 16 | Sulfur release during the devolatilization of large coal particles显示文摘 | FRANCISCO G L JUAN A EDWARD H ALAN W | 1996 | Fuel1996，75，5： | 1 |
| 17 | Application of XPS to coal character- ization 显示文摘 | David l Alan G | 1983 | Fuel1983，62，9： | 1 |
| 18 | The REMATCH trial: rationale, design, and end points显示文摘 | Eric A Rose Alan J Moskowitz Milton Packer Josephine A Sollano Deborah L Williams Anita R Tierney Daniel F Heitjan Paul Meier Deborah Davis Ascheim Ronald G Levitan Alan D Weinberg Lynne Warner Stevenson Peter A Shapiro Ronald M Lazar John T Watson Daniel | 1999 | The Annals of Thoracic Surgery1999，，3： | 1 |
| 19 | Characterization of the myeloid-specific CDllb promoter 显示文摘 | Heike L Alan G Daniel G | 1992 | Blood1992，79，4： | 1 |
| 20 | Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis显示文摘 | Ian R van Driel Alan G Baxter Karen L Laurie Tricia D Zwar Nicole L La Gruta Louise M Judd Katrina L Scarff Pablo A Silveira Paul A Gleeson | 2002 | Autoimmunity Reviews2002，，5： | 1 |
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