|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 2 | Spatial and temporal variation of nitrous oxide and methane flux between subtropical mangrove sediments and the atmosphere显示文摘 | ALLEN D E DALAL R C RENNENBERG H | 2007 | Soil Biology and Biochemistry2007，39，2： | 1 |
| 3 | Strategies for the development of nanocrystalline materials through devitrification显示文摘 | FOLEY J C ALLEN D R PEREPEZKO J H | 1997 | Mater Sci Eng1997，，： | 1 |
| 4 | Effects of components of Artemisia annua on coccidian infections in chickens显示文摘 | Allen P C Lydon J Danforth H D | 1997 | Poultry Science1997，76，： | 1 |
| 5 | Recent advances in biology and immunobiology of Eimeria species and in diagnosis and control of infection with these coccidian parasites of poultry 显示文摘 | Allen P C Fetterer R H | 2002 | Clin Microbiol Rev2002，15，1： | 1 |
| 6 | Adaptation of HIV-1to human leukocyte antigen class I显示文摘 | Kawashima Y Pfafferott K Frater J Matthews P Payne R Addo M Gatanaga H Fujiwara M Hachiya A Koizumi H Kuse N Oka S Duda A Prendergast A Crawford H Leslie A Brumme Z Brumme C Allen T Brander C Kaslow R Tang J Hunter E Allen S Mulenga J Branch S Roach T John M Mallal S Ogwu A Shapiro R Prado J G Fidler S Weber J Pybus O G Klenerman P Ndung'u T Phillips R Heckerman D Harrigan P R Walker B D Takiguchi M Goulder P | 2009 | Nature2009，458，7238： | 1 |
| 7 | Recent damage results on silica/titania reflectors at 1 micron显示文摘 | CARNIGLIA C K APFEL J H ALLEN T H | 1979 | NBS Special Publication1979，568，： | 1 |
| 8 | Zircon Ce^4+/Ce^3+ ratios and ages for Yulong ore-bearing por- phyries in eastern Tibet显示文摘 | Liang Huaying Campbell I H Allen C Sun Weidong Liu Congqiang Yu Hengxiang Xie Yingwen Zhang Yuqiang | 2006 | Miner Deposita2006，41，2： | 1 |
| 9 | Frequent and Variable Cytotoxic-T-Lymphocyte Escape-Associated Fitness Costs in the Human Immunodeficiency Virus Type 1Subtype B Gag Proteins显示文摘 | Boutwell C L Carlson J M Lin T H Seese A Power K A Peng J Tang Y Brumme Z L Heckerman D Schneidewind A Allen TM | 2013 | J Virol2013，87，7： | 1 |
| 10 | The crystal structure of 1,3,5-triamino-2,4,6-trinitrobenzene显示文摘 | Howard H Cady Allen C Larson | 1965 | Acta Cryst1965，18，： | 1 |
| 11 | Correlation of the partitioning of dissolved organic matter fractions with the desorption of Cd, Cu, Ni, Pb and Zn from 18 Dutch soils显示文摘 | Impellitteri C A Lu Y Saxe J K Allen H E Peijnenburg W J G M | 2002 | Environment International2002，28，5： | 1 |
| 12 | Use of an immunoassay as a means to detect polychlorinated biphenyls in animal fat显示文摘 | Jaborek H S Host C V Allen R | 2001 | Food Additives and Contaminants2001，18，2： | 1 |
| 13 | Spatial and tempo- ral variation of nitrous oxide and methane flux between subtropical man- grove sediments and the atmosphere 显示文摘 | ALLEN D E DALAL R C RENNENBERG H Z | 2007 | Soil Biology & Biochemistry2007，39，： | 1 |
| 14 | Ralstonia so- lanacearum needs motility for invasive virulence on tomato显示文摘 | Tans-Kersten J Huang H Allen C | 2001 | J Bacteriol2001，，183： | 1 |
| 15 | A global o- verview of drought and heat-induced tree mortality reveals e- merging climate change risks for forests 显示文摘 | Allen C D Macalady A K Chenchouni H | 2010 | Forest Ecology and Management2010，259，4： | 1 |
| 16 | the Phaeodac- tylum genome reveals the evolutionary history of dia- tom genomes 显示文摘 | Bowler C Allen A E Badger J H | 2008 | Nature2008，456，： | 1 |
| 17 | Calcium binding of Phosphopeptides derived from hydrolysis of αs-casein and β-casein using immobilized trypsin显示文摘 | PARK O SWAISGOOD H E ALLEN J C | 1998 | J Diary Sci1998，81，： | 1 |
| 18 | Effects if ebgabced UV-B radiation (280~320 nm) on ribulise-1,5-bisphos-phate carbox yla se in pea and soybean显示文摘 | VU C V ALLEN L H GARRARD L A | 1983 | Environ Exp Bot1983，23，： | 1 |
| 19 | Resonance-induced hydrogen bonding at sulfur acceptors in RtRzC = S and R~ CSE-systems 显示文摘 | ALLEN F H BIRD C M ROWLAND R S | 1997 | Acta Cryst1997，53，4： | 1 |
| 20 | Advances in biology and immunobiology of eimeria species and in diagnosis and control of infection with these coccidian parasites of poultry 显示文摘 | Allen P C Fetterer R H | 2002 | Clin Microbiol Rev2002，15，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员