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| 1 | Different risk factors influence peptic ulcer disease development in a Brazilian population显示文摘AIM: To investigate age, sex, histopathology and Helicobacter pylori (H. pylori) status, as risk factors for gastroduodenal disease outcome in Brazilian dyspeptic patients.tients submitted to upper gastroscopy at Hospital das Clinicas of Marilia, antral biopsy specimens were obtained and subjected to histopathology and H. pylori diagnosis. All patients presenting chronic gastritis (CG) and peptic ulcer (PU) disease localized in the stomach, gastric ulcer (GU) and/or duodenal ulcer (DU) were included in the study. Gastric biopsies (n = 668) positive for H. pylori by rapid urease test were investigated for vacuolating cytotoxin A (vacA ) medium (m) region mosaicism by polymerase chain reaction. Logistic regression analysis was performed to verify the association of age, sex, histopathologic alterations, H. pylori diagnosis and vacA m region mosaicism with the incidence of DU, GU and CG in patients. RESULTS: Of 1466 patients submitted to endoscopy, 1060 (72.3%) presented CG [male/female = 506/554; mean age (year) ± SD = 51.2 ± 17.81], 88 (6.0%) presented DU [male/female = 54/34; mean age (year) ± SD = 51.4 ± 17.14], and 75 (5.1%) presented GU [male/female = 54/21; mean age (year) ± SD = 51.3 ± 17.12] and were included in the comparative analysis. Sex and age showed no detectable effect on CG incidence (overall c 2 = 2.1, P = 0.3423). Sex [Odds ratios (OR) = 1.8631, P = 0.0058] but not age (OR = 0.9929, P = 0.2699) was associated with DU and both parameters had a highly significant effect on GU (overall c 2 = 30.5, P < 0.0001). The histopathological results showed a significant contribution of ageing for both atrophy (OR = 1.0297, P < 0.0001) and intestinal metaplasia (OR = 1.0520, P < 0.0001). Presence of H. pylori was significantly associated with decreasing age (OR = 0.9827, P < 0.0001) and with the incidence of DU (OR = 3.6077, P < 0.0001). The prevalence of m1 in DU was statistically significant (OR = 2.3563, P = 0.0018) but not in CG (OR = 2.678, P = 0.0863) and GU (OR = 1.520, P = 0.2863). CONCLUSION: In our population, male gender was a risk factor for PU; ageing for GU, atrophy and metapla-sia; and H. pylori of vacA m1 genotype for DU. | Rodrigo Buzinaro Suzuki Rodrigo Faria Cola Larissa Tranquilino Bardela Cola Camila Garcia Ferrari Fred Ellinger Altino Luiz Therezo Luis Carlos da Silva André Eterovic Márcia Aparecida Sperana | 2012 | World Journal of Gastroenterology2012，18，38： | 8 |
| 2 | Clinical and hematological signs associated with dogs naturally infected by Hepatozoon sp. and with other hematozoa: A retrospective study in Uberlandia, Minas Gerais, Brazil显示文摘 | Antonio Vicente Mundim Iara Aparecida de Morais Marcelo Tavares Márcia Cristina Cury Maria José Santos Mundim | 2008 | Veterinary Parasitology2008，，1： | 2 |
| 3 | Energetic-protein supplementation in the last 60 days of gestation improves performance of beef cows grazing tropical pastures显示文摘Background: Nutrition is one of the most important factors that affect animal performance, and it therefore also impacts on financial results in beef systems. In this way, finding the best strategy for feeding supplements is of paramount importance. Aiming to evaluate the effect of supplement feeding strategies for beef cows in the last third of gestation, two experiments were conducted. In Experiment 1, 35 pregnant Nellore cows were assigned to a completely randomized design with four treatments: control, which received no supplement; supplementation for the last 30 d of gestation(30-d; 3.0 kg/d); supplementation for the last 60 d of gestation(60-d; 1.5 kg/d); or supplementation for the last 90 d of gestation(90-d; 1.0 kg/d). All supplemented treatments received the same total amount of supplement throughout the experiment: 90 kg(20% of crude protein). A second experiment(Experiment 2) was delineated to evaluate the effects of the amounts offered in Experiment 1 on intake and metabolism. Four multiparous pregnant Nellore cows were assigned to a 4 × 4 Latin square design, with periods of15 d each.Results: There was a linear effect of the number of days of supplementation on calving body weight(BW; P < 0.05)and a quadratic effect on BW change from parturition to d 31 post-calving(P < 0.05), with cows on the 60-d strategy losing less BW post-calving. No difference was found in offspring birth BW(P > 0.10). A significant linear effect on interval from parturition to conception(P < 0.05) was observed, with the highest calving to conception interval being observed in the 90-d strategy. The level of supplementation did not affect forage intake or neutral detergent fiber digestibility(P > 0.10). Nitrogen excreted through urine tended to increase linearly with the level of supplementation(P < 0.10).Conclusion: Providing 1.5 kg of supplement during the last 60 d of gestation improves cow performance after calving, reducing the magnitude of BW lost, and reduces the number of days from calving to re-conception in the following breeding season compared to the usually recommended period of supplementation of 90 d pre-partum. | Aline Gomes da Silva Mário Fonseca Paulino Edenio Detmann Henrique Jorge Fernandes Lincoln da Silva Amorim Román Enrique Maza Ortega Victor Valério de Carvalho Josilaine Aparecida da Costa Lima Felipe Henrique de Moura Mariana Benevides Monteiro Jéssika Almeida Bitencourt | 2018 | Journal of Animal Science and Biotechnology2018，9，1： | 2 |
| 4 | Salivary Gland Tumor: A Review of 599 Cases in a Brazilian Population显示文摘 | Flávia Aparecida Oliveira Eliza Carla Barroso Duarte Cláudia Teixeira Taveira Aline Abreu Máximo érica Carvalho Aquino Rita de Cássia Alencar Eneida Franco Vencio | 2009 | Head and Neck Pathology2009，，4： | 1 |
| 5 | Anti- cyclic citrullinated peptide antibodies in advanced rheumatoid ar- thritis显示文摘 | Pinheiro GC Scheinberg MA Aparecida da Silva M | 2003 | Ann Intern Med2003，139，3： | 1 |
| 6 | Association of Changes in Bone Remodeling and Coronary Calcification in Hemodialysis Patients: A Prospective Study显示文摘 | Daniela Veit Barreto Fellype de Carvalho Barreto Aluízio Barbosa de Carvalho Lilian Cuppari Sérgio Antonio Draibe Maria Aparecida Dalboni Rosa Maria Affonso Moyses Kátia Rodrigues Neves Vanda Jorgetti Márcio Miname Raul D. Santos Maria Eugênia F. Canziani | 2008 | American Journal of Kidney Diseases2008，，6： | 1 |
| 7 | Adsorption studies of methylene blue and gentian violet on sugarcane bagasse modified with EDTA dianhydride (EDTAD) in aqueous solutions: Kinetic and equilibrium aspects显示文摘 | Karla Aparecida Guimar?es Gusm?o Leandro Vinícius Alves Gurgel Tania Márcia Sacramento Melo Laurent Frédéric Gil | 2013 | Journal of Environmental Management2013，，： | 1 |
| 8 | Thl and Th2 cytokine immunomodulation by gangliosides in experimental autoimmune encephalomyelitis显示文摘 | Monteiro de Castro G Eduarda Zanin M Ventura-Oliveira D Aparecida Vilella C Ashimine R de Lima Zollner R | 2004 | CytoMne2004，26，： | 1 |
| 9 | Separation of Cd and Ni from Ni-Cd batteries by an environmentally safe methodology employing aqueous two-phase systems显示文摘 | VANIA G L APARECIDA B M IGORGOSE B S | 2009 | Journal of Power Sources2009，193，2： | 1 |
| 10 | Pituitary apoplexy during treatment of cystic macroprolactinomas with cabergoline显示文摘 | Giovanna Aparecida Balarini Lima Evelyn de Oliveira Machado Cintia Marques Santos Silva Paulo Niemeyer Filho M?nica Roberto Gadelha | 2008 | Pituitary2008，，3： | 1 |
| 11 | Synthesis of a boronmodified phenolic resin显示文摘 | Aparecida M K Luiz C P Milton F D | 2010 | J Aerosp Techn Manag2010，2，2： | 1 |
| 12 | Inhibition of patulin production by Penicillium expansum cultured with neem(Azadirachta indica)leaf extracts显示文摘 | APARECIDA G M S De OLIVEIRA K P Kemmelmeier C | 2004 | Journal of Basic Microbiology2004，44，2： | 1 |
| 13 | An immuno- cytochemical study of the endocrine cells in the stomach and duodenum of Zonotrichia capensis subtorquata (Passeriformes, Emberizidae)显示文摘 | Rosa M M Aparecida A N Clarice M S | 2009 | Acta Histochemica2009，111，1： | 1 |
| 14 | Synthesis of a boron modified phenolic resin显示文摘 | Aparecida M Kaqamoto Luiz Cláudio Pardini Milton Faria Di-niz | | 0，，02： | 1 |
| 15 | Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds 显示文摘 | Ribeiro Barros Cardoso C Aparecida Souza M Amalia Vieira Ferro E | 2004 | Wound Repair Regener2004，12，2： | 1 |
| 16 | Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds 显示文摘 | Ribeiro Barros Cardoso C Aparecida Souza M Amalia Vieira Ferro E | 2004 | Wound Repair Regener2004，12，2： | 1 |
| 17 | An anatomic study of the septocutaneous vessels of the leg显示文摘 | Carriquiry C Aparecida Costa M Vasconez LO | 1985 | Plast Reconstr Surg1985，76，3： | 1 |
| 18 | Anticyclic citrullinated peptide antibodies in advanced rheumatoid arthritis显示文摘 | Pinheiro G C Scheinberg M A Aparecida da Silva M Maciel S | 2003 | Ann Intern Med2003，139，： | 1 |
| 19 | Immobilization of anionic iron (llI ) porphyrins into ordered macroporous layered double hydroxides and investigation of catalytic activity in oxidation reaction 显示文摘 | Halma M Kelly Aparecida Dias de Freitas Castro Vanessa Prevot | 2009 | Journal of Molecular Catalysis A: Chemical In Press Corrected Proof2009，310，： | 1 |
| 20 | Effect of liver cirrhosis on body composition: Evidence of significant depletion even in mild disease显示文摘 | FáTIMA APARECIDA FERREIRAFIGUEIREDO RENATADE MELLO PEREZ MáRIOKONDO | 2005 | Journal of Gastroenterology and Hepatology2005，，2： | 1 |
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