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107篇 您的检索式：作者名="ARROYO T"

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	题名	作者	年代	出处	被引量
1	Expression of HER2 and bradykinin B_1 receptors in precursor lesions of gallbladder carcinoma显示文摘AIM:To determine the expression of HER2 and bradykinin B 1 receptors(B 1 R) in the two pathogenic models of gallbladder cancer:the metaplasia-dysplasia-carcinoma and the adenoma-carcinoma pathways.METHODS:Receptor proteins were visualized by immunohistochemistry on 5-μm sections of paraffin-embedded tissue.Expression of both receptors was studied in biopsy samples from 92 patients(6 males and 86 females;age ranging from 28 to 86 years,mean 56 years).High HER2 expression in specimens was additionally investigated by fluorescence in situ hybridiza-tion.Cell proliferation in each sample was assessed by using the Ki-67 proliferation marker.RESULTS:HER2 receptor protein was absent in adenomas and in normal gallbladder epithelium.On the contrary,there was intense staining for HER2 on the basolateral membrane of epithelial cells of intestinal metaplasia(22/24;91.7%) and carcinoma in situ(9/10;90%),the lesions that displayed a significantly high proliferation index.Protein up-regulation of HER2 in the epithelium with metaplasia or carcinoma in situ was not accompanied by HER2 gene amplification.A similar result was observed in invasive carcinomas(0/12).The B 1 R distribution pattern mirrored that of HER2 except that B 1 R was additionally observed in the adenomas.The B 1 R appeared either as cytoplasmic dots or labeling on the apical cell membrane of the cells composing the epithelia with intestinal metaplasia(24/24;100%) and carcinoma in situ(10/10;100%) and in the epithelial cells of adenomas.In contrast,both HER2(4/12;33%) and B 1 R(1/12;8.3%) showed a low expression in invasive gallbladder carcinomas.CONCLUSION:The up-regulation of HER2 and B1R in precursor lesions of gallbladder carcinoma suggests cross-talk between these two receptors that may be of importance in the modulation of cell proliferation in gallbladder carcinogenesis.	Cesar Toledo Carola E Matus Ximena Barraza Pamela Arroyo Pamela Ehrenfeld Carlos D Figueroa Kanti D Bhoola Maeva del Pozo Maria T Poblete	2012	World Journal of Gastroenterology2012，18，11：	6
2	Persistent soil seed bank and standing vegetation at a high alpine site in the central Chilean Andes 显示文摘	Arroyo M T K Lohengrin A Castor C C	1999	Oecologia1999，119，：	1
3	Persistent soil seed bank and standing vegetation at a high alpine site in the central Chilean Andes 显示文摘	Mary T Kalin Arroyo Lohengrin A	1999	Oecologia1999，119，：	1
4	The breeding system of Oxalis squamata,a tristylous South American species显示文摘	Marco D E Arroyo M T K	1998	Botanica Acta1998，111，：	1
5	Genetic dysmyelination alters the molecular architecture of the nodal region 显示文摘	Arroyo EJ Xu T Grinspan J	2002	J Neuresci2002，22，5：	1
6	A comparative study of sensor array and GC-MS:application to Madrid wines characterization显示文摘	Santos JP Arroyo T Aleixandre M Lozano J Sayago I García M Femández MJ Arésa L Gutiérrez J Cabellos JM Gil M Horrillo MC		0，，02：	1
7	Risk of upper gastrointestinal ulcer bleeding associated with selective cyclo-oxygenase-2 inhibitors, traditional non-aspirin non-steroidal anti-inflammatory drugs, aspirin and combinations显示文摘	LANAS A GARCIA-RODRIGUEZ L A ARROYO M T	2006	Gut2006，55，12：	1
8	Pericardial fluid postmortem: Comparative study of natural and violent deaths显示文摘	Arroyo A Valero J Marron T	1998	Am J Forensic Med Pathol1998，19，3：	1
9	Finite crystal elasticity of carbon nanotubes based on the exponential Cauchy-Born rule 显示文摘	Arroyo M Belytschko T	2004	Phys Rev B2004，69，11：	1
10	First re port of Fusarium wilt caused by Fusarium oxysporum on strawberry in Spain 显示文摘	ARROYO F T LLERGO Y AGUADO A	2009	Plant Disase2009，93，3：	1
11	Effecl of antisecretory drugs and nitrates on the risk of ulcer bleeding associaled with nonsteroidal anti-inflammatory drugs, antiplalelet agents, and anticoagulants显示文摘	LANAS A GARCIA-RODRIGUEZ L A ARROYO M T	2007	Am J Gastroenterol2007，102，3：	1
12	Characterization of the volatile fraction of young wines from the denomination of origin 'Vinos de Madrid' (Spain)显示文摘	Gil M Cabellos J M Arroyo T	2006	Andytica Chimica Acta2006，563，：	1
13	Theoreticalstudy of the neutral hydrolysis of hydrogen isocyanate inaqueous solution via assisted-concerted mechanisms显示文摘	Arroyo S T Garcia A H Martin JAS	2009	JPhys Chem2009，113，9：	1
14	Development of machine vision and laser radar based autonomous vehicle guidance systems for citrus grove navigation显示文摘	Burks T F Arroyo A A	2006	Computers and Electronics in Agriculture2006，53，2：	1
15	Risk of gastrointestinal bleeding in patients taking low dose aspirin for the prevention of cardiovascular disease 显示文摘	SERRANO P LAVAS F ARROYO M T	2002	Aliment Phar- macol Ther2002，16，11：	1
16	Antifungal activi- ty of strawberry fruit volatile compounds against CoUeto- trichum acutatum 显示文摘	Arroyo F T Moreno J Daza P et at	2007	Journal of Agricultural and Food Chemistry2007，55，14：	1
17	Plant phenological patterns in the high Andean cordillera of central Chile显示文摘	ARROYO M T K ARMESTO J VILLAGRAN C	1981	Journal of Ecology1981，69，：	1
18	Ultrastrueture of the early stages of Colletotrichum acutatum infection of stra- wberry tissues 显示文摘	Arroyo F T Moreno J Garcia-Herdugo G	2005	Canadian Journal of Botany2005，83，5：	1
19	An atomistic-based finite deformation membrane for single layercrystalline films显示文摘	Arroyo M Belytschko T	2002	J Mech Phys Solids2002，50，：	1
20	A matched study of primary scleral buckle placement during repair of posterior segment open globe injuries显示文摘	Arroyo JG Postel EA Stone T	2003	Br J Ophthalmol2003，87，1：	1

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