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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | An efficient synthesis of 3-fluoro-5-thio-xylo-furanosyl nucleosides of thymine, uracil, and 5-fluorouracil as potential antitumor or/and antiviral agents 显示文摘 | TSOUKALA E AGELIS G DOLINSEK J | 2007 | Bioorganic & Medicinal Chemistry2007，15，： | 1 |
| 3 | Activation of toll-like receptor (TLR) 2, TLRA, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation 显示文摘 | Johnson AC Heinzel FP Diaconu E Sun Y Hise AG Golenbock D | 2005 | Invest Ophthalmol Vis Sci2005，46，2： | 1 |
| 4 | Skeletal muscle infarction in diabetes mellitus显示文摘 | Grigoriadis E Fam AG Starok M Ang LC | 2000 | J Rheumatol2000，27，4： | 1 |
| 5 | Serum amyloid A induces CCL20 secretion in mononuclear cells through MAPK(p38 and ERK1/2)signaling pathways显示文摘 | Sandri S Hatanaka E Franco AG | 2008 | Immunology Letters2008，121，1： | 1 |
| 6 | Correlates between hyperinsulinism and hyperandrogenemia? 显示文摘 | Kassi EN Diamanti-Kandarakis E Papavassiliou AG | 2008 | Fertil Steri12008，89，4： | 1 |
| 7 | Proliferative activity of human thy- roid cells in various age groups and its correlation with the risk of thyroid cancer after radiation exposure 显示文摘 | Saad AG Kumar S Ron E | 2006 | J Clin Endocrinol Metab2006，91，7： | 1 |
| 8 | Methylated flavonols in Larrea cuneifolia 显示文摘 | Rodriguez E Velde GV | 1972 | Phytochemistry1972，11，9： | 1 |
| 9 | Autoph-agy is required to maintain muscle mass显示文摘 | MASIERO E AG ATE A L MAMMUCARI C | 2009 | Cell Metab2009，10，6： | 1 |
| 10 | 1 al- pha, 25-dihydroxyvitamin D3 or analogue treated den- dritic cells modulate autoreactive T cells via the selective induction of apoptosis 显示文摘 | van Haheren AG Tysma OM van Etten E | 2004 | J Autoimmun2004，23，3： | 1 |
| 11 | An Insight into the Di- verse Roles of Surfactant Proteins, SP-A and SP-D in Innate and Adap- tive Immunity 显示文摘 | Nayak A Dodagatta-Marri E Tsolaki AG | 2012 | Front Immunol2012，3，： | 1 |
| 12 | Clinical practice guide-line for the use of antimicrobial agents in neutropenic patients withcancer: 2010 Update by the Infectious Disease Society of America显示文摘 | Freifeld AG Bow E J Sepkowitz KA | 2011 | Clin Infect Dis2011，52，4： | 1 |
| 13 | Treatment with interferon-a2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques 显示文摘 | Falzarano D de Wit E Rasmussen AL Feldmann F Oku- mura A Scott DP Brining D Bushmaker T Martellaro C Baseler L Benecke AG Katze MG Munster VJ Feldma- nn H | 2013 | Nat Med2013，19，10： | 1 |
| 14 | Normative nasalance data in Ugandan English-speaking children显示文摘 | Luyten A D'haeseleer E Hodges AG | 2012 | Folia Phoniatr Logop2012，62，： | 1 |
| 15 | Atrial septal pacing to synchonize atrial deplorization in patients with delayed interatrial conduction显示文摘 | Katsivas A Manolis AG Lazaris E | 1998 | PACE1998，21，： | 1 |
| 16 | Prognostic of CD44 splice variant expression in ovarian cancer显示文摘 | Uhl Steidl M Miiller Holzner E Zeimet AG | 1995 | Oncology1995，52，5： | 1 |
| 17 | Genome, transcriptome, and secretome analysis of wood decay fungus Postia placenta supports unique mechanisms of lignocellulose conversion 显示文摘 | Martinez D Challacombe J Morgenstern 1 Hibbett D Schmoll M Kubicek CP Ferreira P Ruiz-Duenas FJ Martinez AT Kersten P Hammel KE Wymelenberg AV Gaskell J Lindquist E Sabat G BonDurant SS Larrondo LF Canessa P Vicuna R Yadav J Doddapaneni H Subramanian V Pisabarro AG Lavin JL Oguiza JA Master E Henrissat B Coutinho PM Harris P Magnuson JK Baker SE Bruno K Kenealy W Hoegger PJ Kties U Ramaiya P kucas S Salamov A Shapiro H Tu H Chee CL Misra M Xie G Teter S Yaver D James T Mokrejs M Pospisek M Grigoriev IV Brettin T Rokhsar D Berka R Cullen D | 2009 | PNAS2009，106，6： | 1 |
| 18 | Func- tional movement screene normative values in a young, active population显示文摘 | Schneiders AG Davidsson A HSrman E | 2011 | The International Journal of Sports Physical Therapy2011，6，2： | 1 |
| 19 | Study of vertebral morphology in Scheuermann's kyphosis before and after treatment显示文摘 | Pola E Lupparelli S Aulisa AG | 2002 | Stud Health Technol Inform2002，91，： | 1 |
| 20 | Mortality associated with congenital syphilis in the united states,1992 ~ 1998显示文摘 | DEBORAH AG WILLIAM CL MICHAEL E | 2002 | Pediatrics2002，109，： | 1 |
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