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| 1 | Molecular and Epidemiological Characterization of Infant Botulism in Beijing, China显示文摘Laboratory-based pathogen isolation, identification, and toxicity determination were performed on samples from a suspected case of infant botulism. Mice injected with cultures generated from the enema sample and ingested Powered infant formula(PIF) presented typical signs of botulism. Antitoxins to polyvalent botulinum neurotoxins(BoNTs) and monovalent BoNT type B antitoxin had protective effects. Clostridium botulinum isolated from the enema and residual PIF samples were positive for type B toxin. Pulsed-field gel electrophoresis(PFGE) revealed that the two strains of C. botulinum isolated from the two samples produced indistinguishable pulsotypes. These findings confirmed this case of type B infant botulism associated with the ingestion of PIF contaminated by type B C. botulinum spores. | DONG Yin Ping WANG Wei JIANG Tao XU Jin HAN Chun Hui YAN Shao Fei Séamus Fanning LI Ying MA Xiao Chen ZHANG Di ZHAO Yao ZENG Biao LI Feng Qin | 2017 | Biomedical and Environmental Sciences2017，30，6： | 4 |
| 2 | Genomic Epidemiology of ST34 Monophasic Salmonella enterica Serovar Typhimurium from Clinical Patients from 2008 to 2017 in Henan,China显示文摘Salmonella enterica serovar 4,[5],12:i:-(S.4,[5],12:i:-)is a monophasic variant of Salmonella enterica serovar Typhimurium that has emerged as a global serovar causing public health concern.To date,the epidemiology and genomic characterization of this pathogen in China have not been well described.We investigated the prevalence,antimicrobial resistance(AMR)phenotypes,and population genomics of sequence type 34(ST34)S.4,[5],12:i:-among cases of human salmonellosis in Henan Province,China.A total of 100 ST34 S.4,[5],12:i:-isolates were studied from 2008 to 2017 and found mostly resistant to ampicillin(AMP),streptomycin(STR),sulfonamides(SUL),and tetracycline(TET)(ASSu T).Bayesian phylogenetic analysis demonstrated that isolates identified in China were mostly related to the European lineage and evolved into two major clades with different resistance genes and plasmid profiles.Notably,clade 1 showed a significantly higher rate of mutations in gyr A and plasmid-mediated quinolone resistance genes.The carrying of the resistance-containing region(encoding R-type ASSu T),including bla(conferring resistance to AMP),str AB(STR),sul2(SUL),and tet(B)(TET)inserted into the flj BA operon,was responsible for most of the monophasic variants in clade 2.Inc HI2 plasmids were the dominant multi-drug resistance mobile genetic elements accounting for the transmission of acquired resistance genes in this serovar,and these were more prevalent in clade 1.Our findings highlighted the increasing prevalence of multi-drug resistant S.4,[5],12:i:-in China,along with the differential characteristics of resistance gene acquisition among various lineages.Based on our data,control measures are required to address the spread of this zoonotic pathogen.Further owing to its potential origin in food-producing animals,a'One Health'approach,should be implemented to support surveillance whilst informing interventional strategies. | Yujiao Mu Ruichao Li Pengcheng Du Pei Zhang Yan Li Shenghui Cui Séamus Fanning Li Bai | 2022 | Engineering2022，8，8： | 2 |
| 3 | Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model 显示文摘 | Amu S Saunders SP Kronenberg M | 2010 | J Allergy Clin Immunol2010，125，： | 1 |
| 4 | Regulatory B cells prevent and reverse allergic airway inflammation via Foxp3 posi tire T regulatory cells in a murine model 显示文摘 | Amu S Saunders SP Kronenberg M | 2010 | J Allergy Clin Im munol2010，125，5： | 1 |
| 5 | Regulatory B cells pre-vent and reverse allergic airway inflammation via FoxP3-positive Tregulatory cells in a murine model显示文摘 | Amu S Saunders SP Kronenberg M | 2010 | J Allergy Clin Immunol2010，5，11： | 1 |
| 6 | Ligation of TLR7 on CD19 CDld B cells suppresses allergic lung inflammation v/a T regulatory cells显示文摘 | Khan A R Amu S Saunders S P | 2015 | Eur J Immunol2015，45，6： | 1 |
| 7 | A numerical study on ground displacement and stress during and after the installation of deep circular diaphragm walls and soil excavation显示文摘 | Arai Yasushi Kusakabe Or amu Murata Osamu | 2008 | Computers and Geotechnics2008，35，： | 1 |
| 8 | Image Analysis by Pseudo-Jacobi (p=4,q=3)-Fourier Moments显示文摘 | Amu Guleng Hasi Surong Yang Xingyu | 2004 | Applied Optics2004，43，10： | 1 |
| 9 | Image Analysis by Pseudo - Jacobi ( p = 4, q = 3 ) - Fourier Moments 显示文摘 | AMU GULENG(阿木古楞) HASI SURONG(哈斯苏荣) YANG XY(杨性愉) | 2004 | Applied Optics2004，43，10： | 1 |
| 10 | Image Analysis by Pseudo-Jacobi ( p = 4, q = 3 )-Fourier Moments 显示文摘 | AMU Guleng Hasi Surong Yang X Y | 2004 | Applied Optics2004，43，10： | 1 |
| 11 | Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3- positive T regulatory cells in a murine model 显示文摘 | Amu S Saunders SP Kronenberg | 2010 | Allergy Clin Immunol2010，125，5： | 1 |
| 12 | Ladder type SAW and its application to high power SAW devices显示文摘 | YOSHI A AMU I | 2000 | International Journal of High Speed Electronie and Systerms2000，10，3： | 1 |
| 13 | Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model 显示文摘 | Amu S Saunders SP Kronenberg M | 2010 | J Allergy Clin Immuno12010，125，： | 1 |
| 14 | Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory ceils in a murine model显示文摘 | Amu S Saunders SP Kronenberg M | 2010 | J Allergy Clin Immuno2010，125，5： | 1 |
| 15 | Image analysis by pseudo-jacobi(p = 4, q = 3)-fourier moments显示文摘 | Guleng Amu Surong Hasi Xingyu Yang Ziliang Ping | 2004 | Applied Optics2004，43，10： | 1 |
| 16 | Connections between precast elements failure outside connection region 显示文摘 | French C W Amu O Tarzikhan C | 1989 | Journal of Structural Engineering1989，115，2： | 1 |
| 17 | Comparison of Salmonella species recovered from Irish liquid milk production holdings with temporal clinical veterinary isolates显示文摘 | Brenda P. Murphy James F. Buckley Elizabeth M. O’Connor Deirdre Gilroy Séamus Fanning | 2007 | International Journal of Hygiene and Environmental Health2007，，3： | 1 |
| 18 | Blockade of B7-H1(pro-grammed death ligand 1)enhances humoral immunity by positivelyregulating the generation of T follicular helper cells显示文摘 | Hams E McCarron MJ Amu S | 2011 | J Im-munol2011，186，10： | 1 |
| 19 | Blockade of B7-H1 (programmed death ligand 1 ) enhanceshumoral immunity by positively regulating the generation of T follicular helpercells 显示文摘 | Hams E McCarron M J Amu S | 2011 | J Immunol2011，186，10： | 1 |
| 20 | Screening for latent tuberculosis in Norwegian health care workers:high fre- quency of discordant tuberculin skin test positive and in- terferon-gamma release assay negative results显示文摘 | Gran G Amus J Dyrhol-Riise AM | 2013 | BMC Public Health2013，13，1： | 1 |
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