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| 1 | Intestinal M cells:The fallible sentinels?显示文摘The gastrointestinal tract represents the largest mucosal membrane surface in the human body. The immune system in the gut is the first line of host defense against mucosal microbial pathogens and it plays a crucial role in maintaining mucosal homeostasis. Membranous or microfold cells, commonly referred to as microfold cells, are specialized epithelial cells of the gut-associated lymphoid tissues (GALT) and they play a sentinel role for the intestinal immune system by delivering luminal antigens through the follicle-associated epithelium to the underlying immune cells. M cells sample and uptake antigens at their apical membrane, encase them in vesicles to transport them to the basolateral membrane of M cells, and from there deliver antigens to the nearby lymphocytes. On the flip side, some intestinal pathogens exploit M cells as their portal of entry to invade the host and cause infections. In this article, we briefly review our current knowledge on the morphology, development, and function of M cells, with an emphasis on their dual role in the pathogenesis of gut infection and in the development of host mucosal immunity. | Harvey Miller Rhonda KuoLee Girishchandra B Patel | 2007 | World Journal of Gastroenterology2007，13，10： | 6 |
| 2 | Hyperspectral vegetation indices and novel algorithms for predicting green LAI of crop canopies: Modeling and validation in the context of precision agriculture显示文摘 | Driss Haboudane John R Miller Elizabeth Pattey Pablo J Zarco-Tejada Ian B Strachan | 2004 | Remote Sensing of Environment2004，，3： | 3 |
| 3 | Variations in zonal fruit starch concentrations of apples – a developmental phenomenon or an indication of ripening?显示文摘Patterns of starch hydrolysis in stem,equatorial,and calyx zones of‘Honeycrisp’and‘Empire’apples(Malus sylvestris(L.)Mill var.domestica(Borkh.)Mansf.)during maturation and ripening,and in‘Gala’apples in response to propylene or 1-methylcyclopropene(1-MCP)treatments after harvest,were studied.Differences in zonal starch concentrations were found for‘Empire’and‘Gala’fruits,but not for‘Honeycrisp’.During maturation and ripening of‘Empire’,the concentration of starch was highest in the calyx end and lowest in the stem region.Differences in rates of starch hydrolysis among zones were not detected.‘Honeycrisp’and‘Empire’had the highest concentration of sorbitol in the calyx region,whereas it was highest in the stem-end region in‘Gala’.The distribution differences of glucose,fructose,and sucrose were similar in all three cultivars;higher fructose and glucose concentrations in the stem region,and higher sucrose concentrations in the calyx end of the fruit.Postharvest treatment of‘Gala’with propylene did not affect the internal ethylene concentration of the fruit but 1-MCP markedly inhibited it.Starch concentrations were highest in the calyx end but gradients of starch among zones were not changed by postharvest treatment.The rate of hydrolysis was slowed by 1-MCP treatment,but was unaffected by propylene.Postharvest treatments influenced sorbitol,glucose,and fructose concentrations.Patterns of starch concentration among the zones did not confirm differences in ripening,but reflected its uneven distribution throughout the fruit during development.Therefore,measured differences in zonal starch are most likely related to starch accumulation during fruit development,rather than differences in rates of starch degradation during ripening. | Franziska C Doerflinger William B Miller Jacqueline F Nock Christopher B Watkins | 2015 | Horticulture Research2015，2，1： | 3 |
| 4 | Solidstate low-loss intracavity saturable absorber for Nd:YLF lasers:An A-FPSA显示文摘 | KELLER U MILLER D A B BOYD G D | 1992 | Opt Lett1992，17，7： | 2 |
| 5 | Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase显示文摘 | Govindarajan B Klafter R Miller MS | 2002 | Mol Med2002，8，1： | 2 |
| 6 | Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Takamaru Ashikaga Donald L Weaver Barbara J Miller Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Denise M Mammolito David R McCready Eleftherios P Mamo | 2007 | Lancet Oncology2007，，10： | 2 |
| 7 | Celluar and molecular diversity in skeletal muscle development:news from in vitro and in vivo显示文摘 | Miller J B Ransey C B Claborn S W | 2000 | Bio Essays2000，15，3： | 2 |
| 8 | What are race conditions? some issues and formalizations 显示文摘 | NETZER R H MILLER B P | 1992 | ACM Letters on Programming Languages and Systems1992，1，1： | 1 |
| 9 | Super-reltron theory and experiments显示文摘 | Miller R B McCullough W F Lancaster K T | 1992 | IEEE Transactions on Plasma Science1992，20，3： | 1 |
| 10 | Solventless determination of caffeine in beverages using solid-phase microextraction with fused-silica fibers显示文摘 | Hawthorne S B Miller D J Pawliszyn J | 1992 | Journal of chromatography1992，603，： | 1 |
| 11 | Visual hallucinosis: clinical occurrence and use in differential di agnosis显示文摘 | Miller B | 1987 | West J Med1987，146，： | 1 |
| 12 | Solving heat exchanger network synthesis problems with Tabu Search显示文摘 | Miller D C | 2004 | Computers and Chemical Engineering2004，28，： | 1 |
| 13 | A comparison between highfinx and plain robes,boiling pentane in a Horizontal Kettle Reboiler显示文摘 | Burnside B M Miller K M Tarrad A H | 2002 | Applied Thermal Engineering2002，22，7： | 1 |
| 14 | Relationship between diurnal blood ressure, renal hemodynamic function, and the rennin angiotensin sys2tem in type 1 diabetes 显示文摘 | Miller J A Curtis J R Schett E B | 2003 | Diabetes2003，52，7： | 1 |
| 15 | Semi-analytical dynamic analysis of spiral-grooved mechanical gas face seals显示文摘 | Miller B A Green I | 2003 | Iournal of Tribology2003，125，： | 1 |
| 16 | Combined use of active and passive surface waves显示文摘 | Park C B Miller R D Ryden N | | Journal of Engineering and Environmental Geophysics (JEEG)0，，： | 1 |
| 17 | Properties of polyether-polyurethane block copolymers : Effect of hard segment lengthdistribution 显示文摘 | Miller J A Lin S B Hwang K K S | 1985 | Macromolecules1985，18，1： | 1 |
| 18 | Flexor tendon repairs:the impact of fiber wire on grasping and locking core sutures显示文摘 | Miller B Dodds SD deMars A | 2007 | J Hand Surg2007，32，5： | 1 |
| 19 | Reporting Resuits of Cancer treatment显示文摘 | Miller A B Hoogstraten B Staquet M | 1981 | Cancer1981，47，： | 1 |
| 20 | Effection of weaning on the capacity of pig intestinal villi to digest and absorb nutrients显示文摘 | Miller B G | 1986 | J Agri Sci1986，107，3： | 1 |
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