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| 1 | Anti-microbial principles of selected remedial plants from Southern India显示文摘Objective:To examine the anti-bacterial activity of leaf extracts of Morus alba L.(Moraceae)and Piper betel L.(Piperaceae),and seed extracts of Bombax ceiba L.(Borabacaceae).Methods:We have partially purified plant extracts by solvent extraction method,and evaluated the effect of individual fractions on bacterial growth using Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa) and Staphylococcus aureus(S.aureus) bacterial strains.Results:Compared with Morus and Bombax fractions,Piper fractions showed significant growth inhibition on all the three types of bacteria studied.The EtOAc-hexane fractions of Piper leaves exhibited significant antibacterial activity with minimum inhibitory concentrations(MIC) of 50 μg/mL culture against both gram-positive and gram-negative bacteria.The EtOAc-fractions Ⅰ,Ⅱ,and Ⅳ inhibited bacterial colony formation on soft agar in addition to growth inhibition.A combination treatment of piper fractions with ampicillin resulted in significant growth inhibition in E.coli and P.aeruginosa,and combination with anticancer drug geldanamycin(2 μg/mL) showed selective growth inhibition against P.aeruginosa and S.aureus.Three major compounds,i.e.,eugenol,3-hexene-ol and stigmasterol,were primarily identified from Piper betel leaf extractions.Among the individual compounds,eugenol treatment showed improved growth inhibition compared with stigmasterol and 3-hexene-ol.Conclusions:We are reporting potential anti-bacterial compounds from Piper betel against both gram-positive and gram-negative bacteria either alone or in combination with drug treatment. | Tirupathi Rao G Suresh Babu K J Ujwal Kumar Sujana P A Veerabhadr Raoa Sreedhar AS | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 5 |
| 2 | Switched bias proportional navigation for homing guidance against highly maneuvering target 显示文摘 | K R Babu J G Sarmah K N Swamy | 1994 | Journal of Guidance Control and Dynamics1994，17，6： | 1 |
| 3 | Tumour reducing and anticarcino genic activity of Acanthus ilicifolius in mice显示文摘 | Babu B H Shylesh B S Padikkala J | 2002 | J Ethnopharmacol2002，79，1： | 1 |
| 4 | Immediate primary skin elosure in type - iii A and B open fractures : results after a minimum of five years 显示文摘 | Rajasekaran S Dheenadhayalan J Babu JN | 2009 | J Bone Joint Surg Br2009，91，： | 1 |
| 5 | Evaluation of bchavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress显示文摘 | Nirmal J Babu CS Harisudhan T | | 0，，： | 1 |
| 6 | Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation显示文摘 | Seibenhener M L Babu J R Geetha T Wong H C Krishna N R Wooten M W | | 0，，18： | 1 |
| 7 | Cytogenetic findings in pituitary adenoma: results of a pilot study 显示文摘 | Babu R Drumheller T | 1993 | Surg Neurol1993，41，： | 1 |
| 8 | Chitosan coat- ings deliver antimicrobials from titanium implants:a pre- liminary study显示文摘 | Norowski PA Courtney HS Babu J | 2011 | Implant Dent2011，20，1： | 1 |
| 9 | Antioxidant and hepatoprotective effect of Acanthus ilicifolius显示文摘 | Babu B H Shylesh B S Padikkala J | 2001 | Fitoterapia2001，72，： | 1 |
| 10 | Peri-procedural myocardial injury during percutaneous coronary intervention: an important target for cardio- protection显示文摘 | BABU G G WALKER J M YELLON D M | 2011 | Eur HeartJ2011，32，： | 1 |
| 11 | Antimicrobial activities of silver used as a polymerization catalyst for a wound-healing matrix 显示文摘 | Babu R Zhang J Beckman EJ | 2006 | Biomaterials2006，27，24： | 1 |
| 12 | Robust object tracking with background-weighted local kernels显示文摘 | Jeyakar J Babu R V Ramakrishnan K R | 2008 | Computer Vision and Image Understanding(S1077-3142)2008，112，3： | 1 |
| 13 | Evaluation of shear strength functions based on soil water characteristic curves显示文摘 | BABU G L S RAO R S PETER J | | 0，，06： | 1 |
| 14 | Correlating implant sta- bility to bone structure 显示文摘 | Roz: J Babu S Saffarzadeh A | 2009 | Clin Oral Implants Res2009，20，10： | 1 |
| 15 | Distribution of organic carbon in surface sediments along the eastern Arabian Sea: a revisit显示文摘 | BABU C P BURMSACK H J SCHNETGER B | 1999 | Marine Geology1999，162，： | 1 |
| 16 | Viral replication is required for induction of ocular tmmunopathology by herpes simplex virus 显示文摘 | Babu JS Thomas J Kanangat S Morrison LA Knipe Dbi Rouse BT | 1996 | J Vlrol1996，70，： | 1 |
| 17 | Synthe- sis, antifungal activity, and structure-activity relation- ships of coruscanone A analogues显示文摘 | BABU K B LI X C MELISSA R J | 2006 | J Med Chem2006，49，26： | 1 |
| 18 | 29- Hydroxymangiferonic acid from Mangifera indica 显示文摘 | ANJANEYULU V BABU J S CONNOLLY J D | 1994 | Phytochemistry1994，35，5： | 1 |
| 19 | Project Management with Time, Cost and Quality Considerations 显示文摘 | Babu A J G Suresh N | 1996 | European Journal Operations Research1996，88，2： | 1 |
| 20 | Acute aortic occlusion factors that influence outcome 显示文摘 | Babu SC Shah PM Nitahara J | 1995 | J Vasc Surg1995，21，4： | 1 |
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