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| 1 | Anti-inflammatory and Antimicrobial Effects of Anthocyanin Extracted from Black Soybean on Chronic Bacterial Prostatitis Rat Model显示文摘Objective: To investigated the anti-inflammatory and antimicrobial effects of anthocyanins extracted from black soybean on the chronic bacterial prostatitis(CBP) rat model.Methods: The SpragueDawley rats were divided into 4 groups,including control,ciprofloxacin,anthocyanins and anthocyanins with ciprofloxacin groups(n=8 in each group).Then,drip infusion of bacterial suspension(Escherichia coli Z17O_2:K_1:H^-) into Sprague-Dawley rats was conducted to induce CBP.In 4 weeks,results of prostate tissue,urine culture,and histological analysis on the prostate were analyzed for each group.Results: The use of ciprofloxacin,anthocyanins,and anthocyanins with ciprofloxacin showed statistically significant decreases in bacterial growth and improvements in the reduction of prostatic inflammation compared with the control group(P<0.05).The anthocyanins with ciprofloxacin group showed a statistically significant decrease in bacterial growth and improvement in prostatic inflammation compared with the ciprofloxacin group(P<0.05).Conclusions: These results suggest that anthocyanins may have anti-inflammatory and antimicrobial effects,as well as a synergistic effect with ciprofloxacin.Therefore,we suggest that the combination of anthocyanins and ciprofloxacin may be effective in treating CBP to obtain a higher rate of treatment success. | Byung Il Yoon Woong Jin Bae Yong Sun Choi Su Jin Kim U Syn Ha Sung-Hoo Hong Dong Wan Sohn Sae Woong Kim | 2018 | Chinese Journal of Integrative Medicine2018，24，8： | 11 |
| 2 | Preparation of agricultural residue anion exchangers and its nitrate maximum adsorption capacity显示文摘 | Orlando U S Baes A U Nishijima W | 2002 | Chemosphere2002，48，： | 1 |
| 3 | Effect of HRT and MLSS on THM precursor removal in the activated sludge process 显示文摘 | Galapate R P Agustian E Baes A U | 1999 | Water Research1999，33，1： | 1 |
| 4 | Laparoscopic-assisted versus open complete mesocolic excision and central vascular ligation for right-sided colon cancer显示文摘 | Bae S U Saklani A P Lim D R | 2014 | Annals of surgical oncology2014，21，7： | 1 |
| 5 | Angular strain estimation method for elastography 显示文摘 | Bae U Kim Y | 2007 | IEEE Trans Uhrason Ferroeleetr Freq Control2007，54，2： | 1 |
| 6 | Inhibition of Proliferation of Prostate Cancer Cell Line DU-145 in vitro and in vivo Using Salvia miltiorrhiza Bunge显示文摘Objective:To investigate the antiproliferative activity of Salvia miltiorrhiza Bunge.(SM)on the castration-resistant prostate cancer(CRPC)cell line DU-145 in vitro and in vivo.Methods:Prostate cancer cell line(DU-145)and normal prostate cell line(RWPE-1)were treated with SM at different concentrations(3.125,12.5,25 and 50μg/mL)to investigate the antiproliferative effects.DNA laddering analysis was performed to investigate the apoptosis of DU-145 cells.Molecular mechanism was investigated by Western blot analysis of p53,Bcl-2,prostate specific antigen(PSA),and androgen receptor(AR).Six-week-old male BALB/c nude mice were randomly divided into normal control group(n=101)and treated group(n=101)which administered 500 mg/kg SM for 2 weeks.Tumor volumes were measured.Results:Treatment with SM resulted in a dose-dependent decrease in cell number of DU-145 cells in comparison with RWPE-1.DNA laddering analysis indicated the apoptosis of DU-145 cells.Treatment with SM increased the expression of p53 and reduced the expression of Bcl-2 proteins.The levels of PSA were considerably reduced in SM-treated group compared to the controls,and a decrease in AR expression was observed when cells were treated with SM in the same pattern as a reduction in PSA.In the tumour xenograft study,SM given once a day for 2 weeks significantly inhibited tumour growth.Conclusion:SM might contribute to the anticancer actions such as induction of apoptosis and inhibition of proliferation of prostate cancer cells. | Woong Jin Bae Jin Bong Choi Kang Sup Kim U Syn Ha Sung Hoo Hong Ji Youl Lee Tae-Kon Hwang Sung Yeoun Hwang WANG Zhi-ping Sae Woong Kim | 2020 | Chinese Journal of Integrative Medicine2020，26，7： | 1 |
| 7 | SPA0355 attenuates ischemia/ Reperfusion-induced liver injury in mice 显示文摘 | Bae U J Yang JD Ka SO | 2014 | Exp Mol Med2014，46，： | 1 |
| 8 | Preparation of agricultural residue anion exchangers and its nitrate maximum adsorption capacity 显示文摘 | Orlando U S Baes A U Nishijima W | 2002 | Chemosphere2002，48，10： | 1 |
| 9 | Cytotoxic Compounds from the Stem Bark of Magnolia obovata 显示文摘 | Min B S Youn U J Bae K H | 2008 | Natur Prodt Sci2008，14，： | 1 |
| 10 | Improvement of extraction method of coagulation active com- ponents from Moringa oleifera seed 显示文摘 | Tetsuji Okuda Aloysius U Baes Wataru Nishijima | 1999 | Water Research1999，，33： | 1 |
| 11 | Preparation of chelating agents from sugarcane bagasse by microwave radiation as an alternative ecolog- ically benign procedure显示文摘 | Orlando U S Baes A U Nishijima W | 2002 | Green Chemistry2002，4，6： | 1 |
| 12 | Chemical properties of anion-exchangers prepared from waste natural materials 显示文摘 | Orlando U S Okuda T Baes A U | 2003 | Reactive and Functional Polymers2003，55，： | 1 |
| 13 | Preparation of agricultural residue anion exchangers and its nitrate maximum adsorption capacity 显示文摘 | Orlando U S Baes A U Nishijima W | 2002 | Chemosphere2002，48，： | 1 |
| 14 | Effect of HRT and MLSS on THM precursor removal in theactivated sludge process显示文摘 | Ritchelita P Galapate Elly Agustiani Aloysius U Baes | 1999 | Water Research1999，33，1： | 1 |
| 15 | Suppression of Oxidative Stress of Modified Gongjin-Dan (WSY^1075) in Detrusor Underactivity Rat Model Bladder Outlet Induced by Obstruction显示文摘Objective: To investigate the anti-oxidative stress and preventive effect of modified Gongjin-dan(WSY-1075) in a detrusor underactivity rat model. Methods: Rats were randomly allocated to three groups: shamoperated(control), bladder outlet obstruction-induced detrusor underactivity(BOO-DU), and BOO-DU with WSY-1075(WSY) groups. WSY-1075 was oral y administrated to rats 200 mg daily for 2 weeks prior to the operation and 4 weeks after the operation. Bladder outlet obstruction was surgical y induced in rats by ligation around the urethra avoiding total obstruction. Cystometrography was conducted on rats in each group for examination of bladders. Results: Compared with the control group, bladder outlet obstruction led to a significant increase in oxidative stress with consequent changes to molecular composition, and decrease in maximal detrusor pressure(P<0.05). WSY-1075 treatment significantly suppressed oxidative stress and prevented degenerative and dysfunctional changes in bladder, as compared with BOO-DU group(P<0.05). Conclusion: WSY-1075 had beneficial effect on prevention of BOO-DU. | Jin-Woo Jung Seung Hwan Jeon Woong Jin Bae Su Jin Kim Mun Su Chung Byung II Yoon Sae Woong Choi U Syn Ha Sung Yeoun Hwang Sae Woong Kim | 2018 | Chinese Journal of Integrative Medicine2018，24，9： | 1 |
| 16 | Ultrasound thyroid elastography using carotid artery pulsation: preliminary study 显示文摘 | Bae U Dighe M Dubinsky T | 2009 | Ultrasound Med2009，26，3： | 1 |
| 17 | High blood pressure in school children:prevalence and risk factors显示文摘 | Ximena Urrutia-Rojas Christie U Egbuchunam Sejong Bae | 2006 | BMC Pediatrics2006，6，： | 1 |
| 18 | Improved brine recy- cling during nitrate removal using ion exchange 显示文摘 | Bae B U Jung Y H Han W W | 2002 | Water Research2002，36，13： | 1 |
| 19 | Laparoscopic - as- sisted versus open complete mesoeolic excision and central vascular ligation for right - sided colon cancer显示文摘 | BAE S U SAKLANI A P LIM D R | 2014 | Annals of surgical oncology2014，21，7： | 1 |
| 20 | A new procedure to produce lignocellulosic anion exchangers from agricultural waste materials 显示文摘 | Orlando U S Baes A U Nishijima W | 2002 | Bioresource Technology2002，83，： | 1 |
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