|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Induction of the apoptosis of cancer cell by sonodynamic therapy:a review显示文摘Ultrasound can be used not only in examination,but also in therapy,especially in the therapy of cancer.Sonodynamic therapy is an experimental cancer therapy method which uses ultrasound to enhance the cytotoxic effects of agents known as sonosensitizers.It has been tested in vitro and in vivo.The ultrasound could penetrate the tissue and cell under some of conditions which directly changes cell membrane permeability,thereby allowing the delivery of exogenous molecules into the cells in some degree.Ultrasound could inhibit the proliferation or induce the apoptosis of cancer cells in vitro or in vivo.Recent researches indicated low-frequency and low-intensity ultrasound could induce cell apoptosis,which could be strengthened by sonodynamic sensitivity,microbubbles,chemotherapeutic drugs and so on.Most kinds of ultrasound suppressed the proliferation of cancer cells through inducing the apoptosis of cancer cells.The mechanism of apoptosis is not clear.In this review,we will focus on and discuss the mechanisms of the induction of cancer cell apoptosis by ultrasound. | Wen-Kun Bai E Shen Bing Hu | 2012 | Chinese Journal of Cancer Research2012，24，4： | 9 |
| 2 | Detecting prostate cancer and prostatic calcifications using advanced magnetic resonance imaging显示文摘前列腺癌症和 prostatic 石灰化在老人有高发生。我们试图在检测前列腺癌症和 prostatic 石灰化调查危险性加权的成像的诊断能力。156 个人的一个全部的数字,与前列腺癌症包括 34 并且 122 在这研究与良性的前列腺被注册。计算断层摄影术,常规磁性的回声成像,散开加权的成像,和危险性加权的成像在所有病人上被执行。112 prostatic 石灰化在 87 个病人被检测。常规磁性的回声成像,明显的散开系数,和在检测前列腺癌症和 prostatic 石灰化的过滤危险性的阶段图象的敏感和特性是计算的。McNemars Chi 平方测试被用来在在这些技术之间的敏感和特性比较差别。结果证明在检测 prostatic 癌症的过滤危险性的阶段图象的敏感和特性比常规磁性的回声成像和明显的散开系数的大(P < 0.05 ) 。另外,在检测 prostatic 石灰化的过滤危险性的阶段图象的敏感和特性比得上计算断层摄影术的并且比常规磁性的回声成像和明显的散开系数的大(P < 0.05 ) 。在前列腺癌症给危险性加权的成像(SWI ) 的高发生反常,我们断定危险性加权的成像在检测前列腺癌症比常规磁性的回声成像,散开加权的成像,和计算断层摄影术更敏感、特定。而且,危险性加权的成像能识别类似于计算断层摄影术的 prostatic 石灰化,并且它比常规磁性的回声成像和散开加权的成像好一些。 | Shewei Dou Yan Bai Ankit Shandil Degang Ding Dapeng Shi E Mark Haacke Meiyun Wang | 2017 | Asian Journal of Andrology2017，19，4： | 7 |
| 3 | Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects. | Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai | 2010 | World Journal of Gastroenterology2010，16，25： | 4 |
| 4 | Ecological rebuilding and land reclamation in surface mines in Shanxi Province, China显示文摘It is well known that the mining industry produces a large amount of derelict land, and causes pollution of water loss and soil erosion as well as other environmental damage in China. As land is under pressure in China, it is now policy to restore or reclaim land despoiled by mining, the aim being to develop sustainable and healthy arable land ecosystems. This paper outlines the principles and approaches of ecological restoration, which have been adopted in Shanxi Province with reference to three typical surface mines. In the research, the principles of ecological engineering and ecological succession are considered as the critical theories of ecological restoration in mine degraded land. Meanwhile, the paper made a comparative research on main links of ecological rebuilding in three surface mines in Shanxi Province, which include new land construction, treatment of toxic substances, control of soil erosion, fertility management, irrigation, ecological planning and the establishment of legislation systems. As the research demonstrated, for successful restoration, new land construction is the fundamental framework, but it must be integrated with ecological engineering including ecological planning, the control of soil erosion and vegetation establishment and ecosystem creation in order to optimise land productivity and soil fertility. In addition, the establishment of the legislation systems and organization of administration are also indispensable aspects of ecological rebuilding in mined land. | MIAO Ze wei 1, BAI Zhong ke 2, GAO Lin 1 (1. Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China E\|mail: miaozewei@yahoo.com 2. Department of Soil Science, Shanxi Agricultural University Taigu, 03 | 2000 | Journal of Environmental Sciences2000，12，4： | 3 |
| 5 | Trace detection of Ce^(3+) by adsorption strip voltammetry at a carbon paste electrode modified with ion imprinted polymers显示文摘To develop a convenient method for sensitive and selective determination of Ce3+ in aqueous phase with complicated matrices, a carbon paste electrode(CPE) modified with ion imprinted polymers(IIPs) were fabricated. The polymers were prepared by precipitation polymerization using Ce3+ as template, allyl phenoxyacetate(APA) as monomer, ethylene glycol dimethacrylate(EGDMA) as crosslinker and azobisisobutyronitrile(AIBN) as initiator under the molar ratio of Ce3+, APA and EGDMA as 1:4:40, respectively. Ce^(3+) was detected directly by differential pulse adsorptive stripping voltammetry(DPASV) and its oxidation peak appears at about 0.93 V. All parameters affecting the sensor's response are optimized and a calibration curve is plotted at a linear range of 1.0 × 10^(-6)-1.0 x 10^(-5) mol/L and 1.0×10^(-5)-2.0 × 10^(-4)mol/L with the detection limit of 1.5 × 10^(-7) mol/L. All other rare earth ions have no interference with the determination of Ce^(3+) even at a concentration 500 times higher than that of Ce^(3+).This sensor was successfully applied to determination of Ce^(3+) in two catalyst sample solutions with RSD≤3.3%(n = 5)and recoveries in the range of 99.2%-106.5% at our optimal conditions. | Jin Chen Huiping Bai Jieren Xia Xiaolan Liu Yanxiong Liu Qiu'e Cao | 2018 | Journal of Rare Earths2018，36，10： | 3 |
| 6 | Response of Soil Organic Carbon and Its Aggregate Fractions to LongTerm Fertilization in Irrigated Desert Soil of China显示文摘Irrigated desert soil samples in the Hexi Corridor of China were collected over a period of 23 years from a site where different fertilization methods had been used. Changes of soil organic carbon(SOC) and its water stable aggregate(WSA) size fractions were studied. The effects of various fertilization methods on the distribution of added organic carbon(OC) in different WSA size fractions were also analyzed. The results showed that the applied fertilizations for 23 years improved SOC concentrations and OC concentrations in all WSA size fractions compared to the non-fertilized treatment(CK). In addition, fertilization obviously increased the OC stocks of <2 mm WSA size fractions compared to the CK. The average OC stock of <0.053 mm WSA fraction was 1.7, 1.6 and 3.2 times higher than those of >2 mm, 0.25-2 mm and 0.053-0.25 mm WSA fractions, respectively. A significant positive correlation was found between soil C gains and OC inputs(r=0.92, P<0.05), indicating that SOC may have not reached the saturation point yet at the site. The C sequestration rate was estimated by 14.02% at the site. The OC stocks in all of the <2 mm WSA fractions increased with the increase of OC input amounts; and the conversion rate of the input fresh OC to the OC stock of <0.053 mm WSA fraction was 1.2 and 2.6 times higher than those of the 0.25-2 mm and 0.053-0.25 mm WSA fractions, respectively. Therefore, the <0.053 mm WSA fraction was the most important component for soil C sequestration in the irrigated desert soil. | CHAI Yan-jun ZENG Xi-bai E Sheng-zhe HUANG Tao CHE Zong-xian SU Shi-ming BAI Ling-yu | 2014 | Journal of Integrative Agriculture2014，13，12： | 3 |
| 7 | Treatment of PC-3 cells with ultrasound combined with microbubbles induces distinct alterations in the expression of Bcl-2 and Bax显示文摘The objective of the present study was to investigate whether ultrasound combined with microbubbles induces apoptotic cell death in androgen-independent prostate cancer cells and to identify the probable mechanism.We used ultrasound in continuous wave mode with a frequency of 21 kHz and a spatial-average temporal-average intensity of 46 mW/cm2.Ultrasound combined with microbubbles(200μL SonoVue)was used to treat androgen-independent human prostate cancer PC-3 cells for 30 s.PC-3 cells were divided into three groups:the control group,the ultrasound group and the ultrasound combined with microbubbles group.Immediately after treatment,trypan blue exclusion was used to assess cell viability.Cell apoptosis at 24 h after treatment was measured using transmission electron microscopy and flow cytometry.Western blotting was used to evaluate the expression of the apoptosis-related proteins,Bcl-2 and Bax.Ultrasound combined with microbubbles had a minimal effect on the viability of PC-3cells and induced minimal levels of cell lysis.The level of apoptosis in PC-3 cells induced by this modality was significantly higher than in controls(12.77±0.31%vs.2.56±0.22%,P<0.01).Treatment with ultrasound combined with microbubbles increased the expression of Bax,a pro-apoptotic protein,and decreased the expression of Bcl-2,an anti-apoptotic protein.It was concluded that ultrasound combined with microbubbles induces apoptotic cell death in human prostate cancer PC-3 cells through down-regulation of Bcl-2 and up-regulation of Bax. | BAI WenKun YANG ShaoLing SHEN E ZHANG JiZhen SHEN ZhiYong HU Bing | 2013 | Chinese Science Bulletin2013，58，28： | 2 |
| 8 | Studies on biosorption of chromium (VI) by dead fungal biomass显示文摘 | Bai S R Abraham T E | 1998 | J Sci Ind Res India1998，57，： | 1 |
| 9 | Property Rights Protection and Access to Bank Loans:Evidence from Private Enterprisesin China显示文摘 | Bai C E LuJ Y Tao Z G | | 0，，04： | 1 |
| 10 | Lung cancer risk in the electroplating industry in Lombardy,Italy,using the Italian occupational cancer monitoring(OCCAM)information system显示文摘 | Panizza C Bai E Oddone E Scaburri A | 2012 | Am J Ind Med2012，55，1： | 1 |
| 11 | An optimal two-stage identification algorithm for Hammerstein-Wiener nonlinear systems 显示文摘 | Bai E W | 1998 | Automatica1998，34，3： | 1 |
| 12 | Strain improvement of Phaffia rhodozyma by protoplast fusion显示文摘 | Chin J E Bai S | 1992 | FEMS Microbiol Lett1992，93，： | 1 |
| 13 | Immunohistochemical study of monocyte chemoattractant protein-1 in the pancreas of NOD mice following cyclophosphamide administration and during spontaneous diabetes显示文摘 | BAI Y ROBINSON E CHAI R | 2006 | J Mol Histol2006，37，34： | 1 |
| 14 | Pharmacokinetics and pharmacodynamics of the erythropoietin mimetibody construct CNTO528 in healthy subjects显示文摘 | Pérez-Ruixo J J Krzyzanski W Bouman-Thio E Miller B Jang H Bai S A | 2009 | Clin Pharmacokinet2009，48，： | 1 |
| 15 | Blind channel estimation in MIMO-OFDM syetems显示文摘 | BAI W CHEN H E JANG L | 2002 | IEICE Trans Comrnun2002，85，9： | 1 |
| 16 | Structure and magnetic properties of N-doped Llo-ordered FePt-C nanocomposite films 显示文摘 | W B Mi E Y Jiang H L Bai | 2006 | J Appl Phys2006，99，03： | 1 |
| 17 | Linear complexity of new generalized cyclotomic sequences of order two of length pq 显示文摘 | Bai E Liu X Xiao G | 2005 | IEEE Transactions on Information Theory2005，51，5： | 1 |
| 18 | Iterative identification of Ham- merstein systems显示文摘 | LIU Y BAI E W | 2007 | Automatiea2007，43，2： | 1 |
| 19 | Property rights protection and access to bank loans:evidence from private enterprises in China显示文摘 | BAI C E LU J TAO Z | 2006 | Economics of Transition2006，，14： | 1 |
| 20 | Electrical stimulation directly induces preangiogenic responses in vascular endothelial cells by signaling through VEGF receptors显示文摘 | ZHAO M BAI H WANG E | 2004 | J Cell Sci2004，117，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员