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| 1 | The role of vascular endothelial growth factor in ossification显示文摘Osteogenesis and angiogenesis are two closely correlated processes during bone growth,development,remodelling and repair. Vascular endothelial growth factor (VEGF) is an essential mediator during the process of angiogenesis. Based on an extensive literature search,which was carried out using the PubMed database and the Keywords of osteogenesis, VEGF, endochondral ossification and intramembranous ossification, this manuscript reviews the role of VEGF in ossification, with emphasis on its effect in endochondral and intramembranous ossification. Osteogenesis and angiogenesis are closely correlated processes. VEGF acts as an essential mediator during these processes. It not only functions in bone angiogenesis but also in various aspects of bone development. | Yan-Qi Yang Ying-Ying Tan Ricky Wong Alex Wenden Lin-Kun Zhang A bakr M Rabie | 2012 | International Journal of Oral Science2012，4，2： | 14 |
| 2 | Early detection of hepatocellular carcinoma co-occurring with hepatitis C virus infection: A mathematical model显示文摘AIM: To develop a mathematical model for the early detection of hepatocellular carcinoma(HCC) with a panel of serum proteins in combination with α-fetoprotein(AFP).METHODS: Serum levels of interleukin(IL)-8, soluble intercellular adhesion molecule-1(s ICAM-1), soluble tumor necrosis factor receptor Ⅱ(s TNF-RⅡ), proteasome, and β-catenin were measured in 479 subjects categorized into four groups:(1) HCC concurrent with hepatitis C virus(HCV) infection(n = 192);(2) HCV related liver cirrhosis(LC)(n = 96);(3) Chronic hepatitis C(CHC)(n = 96); and(4) Healthy controls(n = 95). The R package and different modules for binary and multi-class classifiers based on generalized linear models were used to model the data. Predictive power was used to evaluate the performance of the model. Receiver operating characteristic curve analysis over pairs of groups was used to identify the best cutoffs differentiating the different groups. RESULTS: We revealed mathematical models, based on a binary classifier, made up of a unique panel of serum proteins that improved the individual performance of AFP in discriminating HCC patients from patients with chronic liver disease either with or without cirrhosis. We discriminated the HCC group from the cirrhotic liver group using a mathematical model(-11.3 + 7.38 × Prot + 0.00108 × s ICAM + 0.2574 ×β-catenin + 0.01597 × AFP) with a cutoff of 0.6552, which achieved 98.8% specificity and 89.1% sensitivity. For the discrimination of the HCC group from the CHC group, we used a mathematical model [-10.40 + 1.416 × proteasome + 0.002024 × IL + 0.004096 × s ICAM-1 +(4.251 × 10-4) × s TNF + 0.02567 ×β-catenin + 0.02442 × AFP] with a cutoff 0.744 and achieved 96.8% specificity and 89.7% sensitivity. Additionally, we derived an algorithm, based on a binary classifier, for resolving the multi-class classification problem by using three successive mathematical model predictions of liver disease status. CONCLUSION: Our proposed mathematical model may be a useful method for the early detection of different statuses of liver disease co-occurring with HCV infection. | Abdel-Rahman Nabawy Zekri Amira Salah El-Din Youssef Yasser Mabrouk Bakr Reham Mohamed Gabr Ola Sayed Ahmed Mostafa Hamed Elberry Ahmed Mahmoud Mayla Mohamed Abouelhoda Abeer A Bahnassy | 2016 | World Journal of Gastroenterology2016，22，16： | 2 |
| 3 | Laparoscopic adhesiolysis in acute small bowel obst ruction:a preliminary experience显示文摘 | El Dahha A A Shawkat A M Bakr A A | 1999 | J SLS1999，3，2： | 1 |
| 4 | An Investigation into the Antecedents of the Export Performance Literature显示文摘 | Carlos M Sousa and Bakr A Alserhan | 2002 | Journal of International Business Studies2002，，6： | 1 |
| 5 | Tumor necrosis factor-α production from mononuclear ceils in nephrotic syndrome显示文摘 | Bakr A Shokeir M El-Chenawi F | 2003 | Pediatr Nephrol2003，18，6： | 1 |
| 6 | Influence of hydrogen dilution on structural, electrical and optical properties of hydrogenated nanoerystallinc silicon ( nc-Si: H ) thin films prepared by plasma enhanced chemical vapour deposition(PE-CVD)显示文摘 | Funde A M Bakr N A Kamble D K | 2008 | Solar Energy Materials and Solar Cells2008，92，10： | 1 |
| 7 | Effect of Donor/Recipiem Body Weight Mismatch on Patient and Graft Outcome in Living Donor Kidney Transplantation显示文摘 | E1-Agroudy A E Hassan N A Bakr M A | 2003 | Am J Nephrol2003，，： | 1 |
| 8 | Studies on neurephar- macological profile of ethanol extract of Moringa oleifera leaves in mice显示文摘 | Bakre A G Aderibigbe A O Ademowo O G | 2013 | J Ethnopharmacol2013，149，3： | 1 |
| 9 | Color stability of compomer after immersion in various media 显示文摘 | ABU- BAKR N HAN L OKAMATO A | 2000 | J Esthet Dent2000，，12： | 1 |
| 10 | NPHS2 mutations 显示文摘 | Bakr A Yehia S El- Ghannam D | 2008 | Indian J Pediatr2008，75，2： | 1 |
| 11 | Laparoscopic adhesiolysis in acute small bowel obstruction:a preliminary experience显示文摘 | El Dahha A A Shawkat A M Bakr A A | | 0，，02： | 1 |
| 12 | A technique of duodenal cannulation in sheep显示文摘 | Belge A Bakr B zcelik A | 1980 | J Anita Sci1980，51，1： | 1 |
| 13 | Orthoclase,gypsum and limestone for production of aluminum salt and potassium salt 显示文摘 | Bakr M Y Zatout A A Mouhamed M A | 1979 | Interceram1979，28，1： | 1 |
| 14 | Stochastic analysis of spatial variability in subsurface flows 1:Comparison of one-and three-dimensional flows显示文摘 | ADEL A BAKR ALLAN L GUTJAHR LYNN W GELHAR | | 0，，02： | 1 |
| 15 | Phenolics of Aehillea fragrantissima growing in Egypt and its cytotoxic activity 显示文摘 | Bakr R O Arafa R K AI-Abd A M | 2014 | J Med Plants Res2014，8，21： | 1 |
| 16 | Implementation and Performance Evaluation of Indirect TCP显示文摘 | A V Bakre B R Badrinath | 1997 | IEEE Transactions on Computers1997，46，3： | 1 |
| 17 | Effect of alumina on ceramic properties of cordierite glass-ceramic from basalt rock显示文摘 | Salwa A M Abdel H Bakr I M | 2007 | Journal of the European Ceramic Society2007，27，23： | 1 |
| 18 | Epidemiology treatment and outcome of childhood systemic lupus erythematosus in Egypt显示文摘 | Bakr A | 2005 | Pediatr Nephrol2005，20，： | 1 |
| 19 | Generation of muhipoten- tim mesendodermal progenitors from mouse embryonic stem cells via sustained Wnt pathway activation显示文摘 | Bakre M M Hoi A Mong J C | 2007 | J Biol Chem2007，282，31： | 1 |
| 20 | A comparative study of two angiogenic factors:vascular endothelial growth factor and angiogenin in induced sputum from asthmatic children in acute attack显示文摘 | Abdel-Rahman A M el-Sahrigy S A Bakr S I | 2006 | Chest2006，129，2： | 1 |
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