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1Peritoneal carcinomatosis of colorectal origin显示文摘Peritoneal carcinomatosis is,after liver metastases,the second most frequent cause of death in colorectal cancer patients and at the present time,is commonly inserted and treated as a stage Ⅳ tumour.Because there is no published data that outlines the impact of new therapeutic regimens on survival of patients with peritoneal surface diffusion,the story of carcinomatosis can be rewritten in light of a new aggressive approach based on the combination of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.Also if these treatment perhaps allow to obtain better results than standard therapies,we suggest,that a large prospective randomised control trial is needed to compare long-term and progression-free survival under the best available systemic therapy with or without cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.Antonio Macrì Edoardo Saladino Vincenzo Bartolo Vincenzo Adamo Giuseppe Altavilla Epifanio Mondello Giovanni Condemi Angelo Sinardi Ciro Famulari 2010World Journal of Gastrointestinal Oncology2010,2,2:3
2Effectiveness of very low-volume preparation for colonoscopy:A prospective, multicenter observational study显示文摘BACKGROUND The effectiveness of colonoscopy strictly depends on adequate bowel cleansing.Recently,a 1 L polyethylene glycol plus ascorbate(PEG-ASC)solution(Plenvu;Norgine,Harefield,United Kingdom)has been introduced on the evidence of three phase-3 randomized controlled trials,but it had never been tested in the real-life.AIM To assess the effectiveness and tolerability of the 1 L preparation compared to 4 L and 2 L-PEG solutions in a real-life setting.METHODS All patients undergoing a screening or diagnostic colonoscopy after a 4,2 or 1 L PEG preparation,were consecutively enrolled in 5 Italian centers from September 2018 to February 2019.The primary endpoints of the study were the assessment of bowel cleansing success and high-quality cleansing of the right colon.The secondary endpoints were the evaluation of tolerability,adherence and safety of the different bowel preparations.Bowel cleansing was assessed through the Boston Bowel Preparation Scale.Adherence was defined as consumption of at least 75%of each dose,while tolerability was evaluated through a semiquantitative scale.Safety was systematically monitored through adverse events reporting.RESULTS Overall,1289 met the inclusion criteria and were enrolled in the study.Of these,490 patients performed a 4 L-PEG preparation(Selgesse^■),566 a 2 L-PEG cleansing(Moviprep^■or Clensia^■)and 233 a 1 L-PEG preparation(Plenvu^■).Bowel cleansing by Boston Bowel Preparation Scale was 6.5±1.5 overall and 6.3±1.5,6.2±1.5,7.3±1.5(P<0.001)in the subgroups of 4 L,2 L and 1 L-PEG preparation,respectively.Cleansing success was achieved in 72.4%,74.1%and 90.1%(P<0.001),while a high-quality cleansing of the right colon in 15.9%,12.0%and 41.4%(P<0.001)for 4 L,2 L and 1 L-PEG preparation groups,respectively.The 1 L preparation was the most tolerated compared to the 2 and 4 L-PEG solutions in the absence of serious adverse events within any of the three groups.Multiple regression models confirmed 1 L PEG-ASC preparation as an independent predictor of overall cleansing success,high-quality cleansing of the right colon and of tolerability.CONCLUSION This study supports the effectiveness and tolerability of 1 L PEG-ASC,also showing it is an independent predictor of overall cleansing success,high-quality cleansing of the right colon and of tolerability.Marcello Maida Emanuele Sinagra Gaetano Cristian Morreale Sandro Sferrazza Giuseppe Scalisi Dario Schillaci Marco Ventimiglia Fabio Salvatore Macaluso Giovanni Vettori Giuseppe Conoscenti Concetta Di Bartolo Serena Garufi Domenico Catarella Michele Manganaro Clara Maria Virgilio Salvatore Camilleri 2020World Journal of Gastroenterology2020,26,16:2
3Four-week trunk-specific rehabilitation treatment improves lateral trunk flexion in parkinson’s disease显示文摘Bartolo M Serrao M Tassorelli C 2010Movement disorders2010,25,3:1
4Effects of triclosan- containing rinse on the dynamics and antimicrobial susceptibility of in vitro plaque ecosystems 显示文摘McBain A J Bartolo R G Catrenich C E et ol 2003Antimicrob Agents Chemother2003,47,:1
5Spectrum of small mutations in the dystrophin coding region显示文摘Prior TW Bartolo C Pearl DK 1995Am J Hum Genet1995,57,1:1
6Cal- cium and osteoprotegerin regulate IGFlR expression to inhibit vascular calcification显示文摘DI BARTOLO BA SCHOPPET M MATTAR MZ 2011Cardiovasc Res2011,91,3:1
7Calcium and osteoprotegerin regulate IGF1R expression to inhibit vascular calcification显示文摘Di Bartolo B A Schoppet M Mattar M Z 2011Cardiovasc Res2011,91,3:1
8Calcium and osteprotegerin regulate IGF 1R expression to inhibit vascular calcification 显示文摘Di Bartolo BA Schoppet M Mattar Mz 2011Cardiovasc Res2011,91,3:1
9Diabetes Interactive Diary: a new telemedicine system enabling flexible diet and insulin therapy while improving quality of life : an open - label, international, multicenter, randomized study 显示文摘ROSSI M C NICOLUCCI A DI BARTOLO P D 2010Diabetes Care2010,33,1:1
10Caregivers burden and needs in community neurorehabilitation 显示文摘Bartolo M De Luca D Serrao M 2010J Rehabil Med2010,42,9:1
11Artificial anal sphincter显示文摘Wong WD Jensen LL Bartolo DCC 1996Dis Colon Rectum1996,39,12:1
12Mn oxide fihn as corrosion inhibition of Zn-Mn coatings 显示文摘Diaz L B Ramanauskas R Bartolo P P 2000Corrosion Reviews2000,18,1:1
13The effect of surface roughness of microporous membranes on the kinetics of oxygen consumption and ammonia elimination by adherent hepatocytes显示文摘De Bartolo L Catapano G Delia Volpe C 1999J Biomater Sci Polym Ed1999,10,:1
14Proctalgia fugax 显示文摘Potter M A Bartolo D C 2001European J Gastroenterol Hepato12001,13,:1
15Combined effect of oxygen and ammonia on the kinetics of ammonia elimination and oxygen comsumption of adherent rat liver cells显示文摘Catapano G De Bartolo L 2002Int J Artif Organs2002,25,2:1
16The IMGC Calibration Setup for Micro- displacement Actuators显示文摘Attilio Sacconi Gian Bartolo Picotto Walter Pasin 1999IEEE Transactions on Instrumentation and Measurement1999,48,2:1
17Injection of inu-avitreal bevac-izumab ( Avasrin ) as a preoperative adjunct before vitrectomy surgery in the treatment of severe proliferative diabetic retinopathy (POll)显示文摘Rizzo S Genovesi-Eberl F di Bartolo E 2008Graefe''s Arch Clin Exp Ophthalmol2008,246,:1
18Tailoring T-cell receptor signals by proximal negative feedback mechanisms显示文摘Acuto O Di Bartolo V Michel F 2008Nat Rev Immunol2008,8,9:1
19Detection and characterization of porcine caliciviruses in Italy显示文摘Di Bartolo I Tofani S Angeloni G 2014Archives of Virology2014,159,9:1
20Injection ofintravitreal bevacizumab ( Avastin) as a preoperative adjunct beforevitrectomy surgery in the treatment of severe proliferative diabeticretinopathy ( PDR) 显示文摘Hizzo S Genovesi-Ebert F Di Bartolo E 2008Graefes Arch Clin Exp Ophthalmol2008,246,6:1
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