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| 1 | Risk-adjustment in hepatobiliarypancreatic surgery显示文摘AIM: The present study evaluates the performance of the POSSUM, the American Society of Anesthetists (ASA),APACHE and Childs classification in predicting mortality and morbidity in hepatopancreaticobiliary (HPB) surgery.We describe especially the limitations and advantages of risk in stratifying the patients.METHODS: We investigated 177 randomly chosen patients undergoing eledive complex HPB surgery in a single institution with a total of 71 pre-operative and intra-operative risk factors.Primary endpoint was in-hospital mortality and morbidity.Ordered logistic regression analysis was used to identify individual predictors of operative morbidity and mortality.RESULTS: The operative mortality in the series was 3.95% .This compared well with the p-POSSUM and APACHE predicted mortality of 4.31% and 4.29% respectively. Postoperative complications amounted to 45% with 24 (13.6%)patients having a major adverse event. On multivariate analysis the pre-operative POSSUM physiological score (OR = 1.18,P = 0.009) was superior in predicting complications compared to the ASA (P = 0.108), APACHE (P = 0.117)or Childs classification (P = 0.136). In addition, serum sodium, creatinine, international normalized ratio (INR),pulse rate, and intra-operative blood loss were independent risk factors. A combination of the POSSUM variables and INR offered the optimal combination of risk factors for risk prognostication in HPB surgery.CONCLUSION: Morbidity for elective HPB surgery can be accurately predicted and applied in everyday surgical practice as an adjunct in the process of informed consent and for effective allocation of resources for intensive and high-dependency care facilities. | Hemant M Kocher Paris P Tekkis Palepu Gopal Ameet G Patel Simon Cottam Irving S Benjamin | 2005 | World Journal of Gastroenterology2005，11，16： | 3 |
| 2 | 遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人, | 刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM | 2017 | 中华高血压杂志2017，25，2： | 2 |
| 3 | Condensed tannin biosynthesis genes are regulated separately from other flavonoid biosynthesis genes in apple fruit skin显示文摘 | Adam M T Benjamin E U Robinson S P | 2006 | Plant Science2006，170，： | 1 |
| 4 | Vorapaxar for secondary prevention of thrombotic events for patients with previous myocardial infarction: a prespecified subgroup analysis of the TRA 2°P-TIMI 50 trial显示文摘 | Benjamin M Scirica Marc P Bonaca Eugene Braunwald Gaetano M De Ferrari Daniel Isaza Basil S Lewis Felix Mehrhof Piera A Merlini Sabina A Murphy Marc S Sabatine Michal Tendera Frans Van de Werf Robert Wilcox David A Morrow | 2012 | The Lancet . 2012 (9850)2012，，9850： | 1 |
| 5 | Mutation scanning of the p53 tumor suppressor gene in renal and liver transplant patients in Hungary 显示文摘 | Sarvary E Nagy P Benjamin A Szoke M Remport A Jansen J | 2005 | Transpl Proc2005，37，： | 1 |
| 6 | Expression of NOTCH-1 and Its Ligands, Delta-Like-1 and Jagged-1, Is Critical for Glioma Cell Survival and Proliferation显示文摘 | Benjamin W P Raqeeb M H Martha W N etal | 2005 | Cancer Res2005，65，6： | 1 |
| 7 | Glucagon-like peptide-2 enhances intestinal epithelial barrier function of both transcellular and paracellular pathways in the mouse显示文摘 | BENJAMIN M A McKAY D M YANG P C | 2000 | Gut2000，47，1： | 1 |
| 8 | Cellular automaton models of traffic flow along a highway containing a junction显示文摘 | BENJAMIN S C JOHNSON N F HUI P M | 1996 | J phys A1996，29，： | 1 |
| 9 | Cellular au tomaton models of tra//ic flow along a highway con taining a junction显示文摘 | Benjamin S C Johnson N F Hui P M | 1996 | Physica A1996，29，31： | 1 |
| 10 | Supercritical water oxidation of methylamine显示文摘 | Benjamin K M Savage P E | 2005 | Industrial&Engineering Chemistry Research2005，44，14： | 1 |
| 11 | Effects of silicon on the crystallization and adsorption properties of ferric oxides显示文摘 | Anderson P R Benjamin M M | 1985 | Environmental Science and Technology1985，19，11： | 1 |
| 12 | Multiple Large Shareholders and Firm Va- lue显示文摘 | Benjamin M Anete P | 2008 | Journal of Banking and Finance2008，29，7： | 1 |
| 13 | Multi-player quantum games显示文摘 | HAYDEN P M | 2001 | Phys Rev A2001，64，03： | 1 |
| 14 | Nontoxic strains of cyanobacteria are the result of major gene deletion events induced by a transposable element显示文摘 | Guntram C Carole M Benjamin P | 2008 | Molecular Biology and Evolution2008，25，8： | 1 |
| 15 | Toward a Theory of International New Ventures显示文摘 | Oviatt Benjamin M McDougall Patricia P | 1994 | Journal of International Business Studies1994，25，1： | 1 |
| 16 | Charac- terization of Rac and Cdc42 Activation in Chemoattractant-stim- ulated Human Neutrophiis Using a Novel Assay for Active GT- Pases 显示文摘 | Valerie Benard Benjamin P Bohl Gary M Bokoch | 1999 | The Journal of Biological Chemistry1999，，13： | 1 |
| 17 | Multiplayer quantum games显示文摘 | Benjamin S C Hayden P M | 2001 | Physical Review A2001，64，： | 1 |
| 18 | A novel ion exchange process as As removal显示文摘 | Kim J Benjamin M M Kwan P Chang Y | 2003 | Am Water Works Assoc J2003，95，3： | 1 |
| 19 | Introduction to the spe-cial issue on graphical models and information retrieval显示文摘 | Juan M F Juan F H Benjamin P | 2009 | Journal of Approximate Reasoning2009，50，7： | 1 |
| 20 | Dietary nitrate-Good or bad显示文摘 | Gilchrist M Winyard P G Benjamin N | | 0，，2： | 1 |
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