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| 1 | The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。 | Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] | 2012 | Cell Research2012，22，1： | 12 |
| 2 | The Global Standard Stratotype-section and Point (GSSP) for the base of the Eocene Series in the Dababiya section (Egypt)显示文摘 | Marie-Pierre Aubry Khaled Ouda Christian Dupuis William A., Berggren John A. Van Couvering 无 | 2007 | Episodes2007，30，4： | 8 |
| 3 | Phylogenetic inferences in Prunus (Rosaceae) using chloroplast ndhF and nuclear ribosomal ITS sequences显示文摘Sequences of the chloroplast ndhF gene and the nuclear ribosomal ITS regions are employed to recon-struct the phylogeny of Prunus (Rosaceae), and evaluate the classification schemes of this genus. The two data sets are congruent in that the genera Prunus s.l. and Maddenia form a monophyletic group, with Maddenia nested within Prunus. However, the ndhF data set is incongruent with the ITS data supporting two major groups within Prunus: one consisting of subgenera Laurocerasus (including Pygeum) and Padus as well as the genus Maddenia and another of subgenera Amygdalus, Cerasus, and Prunus. The ITS data, on the other hand, support a clade composed of subgenera Amygdalus and Prunus and Prunus sect. Microcerasus in addition to a paraphyletic grade of subgenera Laurocerasus and Padus (and the genus Maddenia) taxa. In general, the subgeneric classifications of Prunus s.l. are not supported. The ITS and ndhF phylogenies differ mainly in interspecific relationships and the relative position of the Padus/Laurocerasus group. Both ITS and ndhF data sets suggest that the formerly recog-nized genus Pygeum is polyphyletic and that the distinction of the subgenera Padus and Laurocerasus is not supported. The biogeographic interactions of the temperate and tropical members in the Padus/Laurocera- sus/Maddenia alliance including Pygeum are shown to be highly dynamic and complex. | Jun WEN Scott T. BERGGREN Chung-Hee LEE Stefanie ICKERT-BOND Ting-Shuang YI Ki-Oug YOO Lei XIE Joey SHAW Dan POTTER | 2008 | 植物分类学报2008，46，3： | 7 |
| 4 | 湿地和湖泊:氮的储集库显示文摘近15年中,由于过量氮的负荷造成的富营养化在瑞典南部沿海水域已成为越来越严重的问题。现在的政策规定的目标是到1996年以前人为排放氮要减少50%。在这方面主要的问题是从农田排出的氮。因此,作者研究了瑞典南部农业区不同类型湿地对氮的存储容量,以确定湿地是否可用于减少从农田排放到近海海洋生态系统中去的氮。同时也对不断增加氮负荷的湖泊中氮的持留机制进行了研究。其结果表明,在湿地氮的去除主要决定于脱氮作用。此外,在湖泊中的沉积作用也是举足轻重的。水的存留时间乃是去除氮最关键的因素。因此,尽管氮存留率(每平方米氮的持留量)在湿地中是相当大的,但湖泊去除的氮还是比小的湿地要更多些。池塘被推荐为去除氮的最合适的湿地类型。在瑞典南部用湿地作为减少氮迁移的一种方法,其最大的问题是由于冬季高流量期间,氮存留在湿地中的时间太短,而使生物去除过程,如脱氮作用不能充分发挥其效用。在集水区中在大尺度范围中建立大量湿地最多可能使氮的迁移减少约15%。在多数情况中,其结果可能更小些。 | Mats Jansson Rune Andersson Hans Berggren Lars Leonardson 汪安璞 | 1994 | 人类环境杂志1994，23，6： | 4 |
| 5 | Increased expression of mitochondrial peroxiredoxin-3 (thioredoxin peroxidase-2) protects cancer cells against hypoxia and drug-induced hydrogen peroxide-dependent apoptosis 显示文摘 | Nonn L Berggren M Powis G | 2003 | Mol Cancer Res2003，1，9： | 1 |
| 6 | Dental fear and avoidance: causes symptoms and consequence 显示文摘 | Berggren U Megnert G | 1984 | J Am Dent Assoc1984，109，2： | 1 |
| 7 | Long-term management of the fearful adult patient using behavior modification and other modalities显示文摘 | Berggren U | 2001 | J Dent Educ2001，65，12： | 1 |
| 8 | Observation of high-energy deuterium-tritium fusion gamma rays using gas Cherenkov detec- tors显示文摘 | Mack J M Berggren R R Caldwell S E | 2003 | Nucl Instrum Meth Phys Res A2003，513，56： | 1 |
| 9 | Long-term N addition effects on the C mineralization and DOC production in morhumus under spruce显示文摘 | Sjoberg G Bergkvist B Berggren D | 2003 | Soil Biology and Biochemistry2003，35，： | 1 |
| 10 | Managing uncertain complex product development in high-tech firms In search of controlled flexibility显示文摘 | Olausson D Berggren C | 2010 | RD Man agement2010，40，4： | 1 |
| 11 | Acute confusional states in elderly patients treated for femoral neck fracture显示文摘 | Gustafson Y Berggren D Brnnstrm B | 1988 | J Am Geriatr Soc1988，36，6： | 1 |
| 12 | The role of organic matter in controlling aluminum solubility in acidic mineral soil horizons 显示文摘 | Berggren D Mulder J | 1995 | Geoehim Cosmochim Acta1995，59，： | 1 |
| 13 | Study of the kinetics of the mechanism of solid-state reactions at increasing temperatures显示文摘 | Jaroslav Sestak Gunnar Berggren | 1971 | Thermochimica Acta1971，3，： | 1 |
| 14 | Surgical removal of pulmonary metastases from renal cell carcinoma显示文摘 | Dernevik L Berggren H Larsson S | 1985 | Scand J Urol Nephrol1985，19，2： | 1 |
| 15 | Sedation for fibreoptic gastroscopy:a comparative study of midazolem and diazepam显示文摘 | Berggren L Eriksson I Mollenholt P | 1985 | Br J Anaesth1985，55，4： | 1 |
| 16 | Switchablecharge traps in polymer diodes 显示文摘 | Andersson P Robinson N D Berggren M | 2005 | Adv Mater2005，17，： | 1 |
| 17 | Organization of acute pain services: a low-cost model显示文摘 | Rawal N Berggren L | 1994 | Pain1994，57，11： | 1 |
| 18 | Prenatal ultrasound detection of cleft lip,or cleft palate,or both,in southern Sweden,2006-2010显示文摘 | Berggren H Hansson E Uvemark A | 2012 | Journal of plastic surgery and hand surgery2012，46，2： | 1 |
| 19 | Alterations of riparian ecosys- tems caused by river regulation 显示文摘 | Nilsson C Berggren K | 2000 | BioScience2000，50，9： | 1 |
| 20 | Differential effect on cell-mediated immunity in human volunteers after intake of dif- ferent lactobacilli显示文摘 | Rask C Adlerberth I Berggren A | 2013 | Clin & Exp Immunol2013，172，2： | 1 |
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