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| 1 | Distribution of bleeding gastrointestinal angioectasias in a Western population显示文摘AIM:To define which segments of the gastrointestinal tract are most likely to yield angioectasias for ablative therapy. METHODS:A retrospective chart review was performed for patients treated in the Louisiana State University Health Sciences Center Gastroenterology clinics between the dates of July 1, 2007 and October 1, 2010. The selection of cases for review was initiated by use of our electronic medical record to identify all patients with a diagnosis of angioectasia, angiodysplasia, or arteriovenous malformation. Of these cases, chart reviews identified patients who had a complete evaluation of their gastrointestinal tract as defined by at least one upper endoscopy, colonoscopy and small bowel capsule endoscopy within the past three years. Patients without evidence of overt gastrointestinal bleeding or iron deficiency anemia associated with intestinal angioectasias were classified as asymptomatic and excluded from this analysis. Thirty-five patients with confirmed, bleeding intestinal angioectasias who had undergone complete endoscopic evaluation of the gastrointestinal tract were included in the final analysis. RESULTS:A total of 127 cases were reviewed. Sixtysix were excluded during subsequent screening due to lack of complete small bowel evaluation and/or lack of documentation of overt bleeding or iron deficiency anemia. The 61 remaining cases were carefully examined with independent review of endoscopic images as well as complete capsule endoscopy videos. This anal- ysis excluded 26 additional cases due to insufficient records/images for review, incomplete capsule examination, poor capsule visualization or lack of confirmation of typical angioectasias by the principal investigator on independent review. Thirty-five cases met criteria for final analysis. All study patients were age 50 years or older and 13 patients (37.1%) had chronic kidney disease stage 3 or higher. Twenty of 35 patients were taking aspirin (81 mg or 325 mg), clopidogrel, and/or warfarin, with 8/20 on combination therapy. The number and location of angioectasis was documented for each case. Lesions were then classified into the following segments of the gastrointestinal tract:esophagus, stomach, duodenum, jejunum, ileum, right colon and left colon. The location of lesions within the small bowel observed by capsule endoscopy was generally defined by percentage of total small bowel transit time with times of 0%-9%, 10%-39%, and 40%-100% corresponding to the duodenum, jejunum and ileum, respectively. Independent review of complete capsule studies allowed for deviation from this guideline if capsule passage was delayed in one or more segments. In addition, the location and number of angioectasias observed in the small bowel was further modified or confirmed by subsequent device-assisted enteroscopy (DAE) performed in the 83% of cases. In our study population, angioectasias were most commonly found in the jejunum (80%) followed by the duodenum (51%), stomach (22.8%), and right colon (11.4%). Only two patients were found to have angioectasias in the ileum (5.7%). Twenty-one patients (60%) had angioectasias in more than one location.CONCLUSION:Patients being considered for endoscopic ablation of symptomatic angioectasias should undergo push enteroscopy or anterograde DAE and reinspection of the right colon. | Elizabeth Bollinger Daniel Raines Patrick Saitta | 2012 | World Journal of Gastroenterology2012，18，43： | 5 |
| 2 | Molecular genetic analysis of response of three soil microbial communities to the application of 2,4-D 显示文摘 | Xia X Bollinger J Ogram A | 1995 | Molecular Ecology1995，4，： | 2 |
| 3 | Appendectomy and Clostridium difficile colitis:Relationships revealed by clinical observations and immunology显示文摘Advances in understanding the interaction between the human immune system and the microbiome have led to an improved understanding of the function of the vermiform appendix as a safe-house for beneficial bacteria in the colon.These advances have been made despite long standing clinical observations that the appendectomy is a safe and effective procedure.However,more recent clinical data show that an appendectomy puts patients at increased risk for recurrent Clostridium difficile(C.difficile)-associated colitis,and probably other diseases associated with an altered microbiome.At the same time,appendectomy does not apparently put patients at risk for an initial onset of C.difficile-associated colitis.These clinical observations point toward the idea that the vermiform appendix might not effectively protect the microbiome in the face of broad spectrum antibiotics,the use of which precedes the initial onset of C.difficile-associated colitis.Further,these observations point to the idea that historically important threats to the microbiome such as infectious gastrointestinal pathogens have been supplanted by other threats,particularly the use of broad spectrum antibiotics. | Nathan L Sanders R Randal Bollinger Ryan Lee Steven Thomas William Parker | 2013 | World Journal of Gastroenterology2013，19，34： | 2 |
| 4 | As(V) retention and As(III) simultaneous oxidation and removal on a MnO 2 -loaded polystyrene resin显示文摘 | Véronique Lenoble Christelle Laclautre Bernard Serpaud Véronique Deluchat Jean-Claude Bollinger | 2004 | Science of the Total Environment2004，，1： | 2 |
| 5 | Surgical approach to functional tricuspid regurgitation: should we be more aggressive?显示文摘 | Jason H. Rogers Steven F. Bolling | 2014 | Current Opinion in Cardiology2014，，2： | 2 |
| 6 | Grading the severity of congestive heart failure in infants显示文摘 | Ross RD Bollinger RO Pinsky WW | 1992 | Pediatr Cardiol1992，13，： | 1 |
| 7 | Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India,with evidence of intersubtype recombination显示文摘 | Lole KS Bollinger RC Paranjape RS Gadkari D | 1999 | J Virol1999，73，1： | 1 |
| 8 | Gene expression in Pseudomonas aeruginosa:evidence of iron override effects on quorum sensing and biofilm-specific gene regulation显示文摘 | Bollinger N Hassett DJ Iglewski BH | 2001 | J Bacteriol2001，183，： | 1 |
| 9 | Rare earth elements incold seep carbonates from the Niger delta 显示文摘 | Rongemaille E Bayon G Pierre C Bollinger C Chu N C Fouquet Y Riboulot V Voisset M | 2011 | Chem Geol2011，286，19： | 1 |
| 10 | Estimation of the abun-dance of an uncultured soil bacterial strain by a competitive quan-titative PCR method显示文摘 | Lee SY Bollinger J Bezdicek D | 1996 | Appl Environ Microbiol1996，62，10： | 1 |
| 11 | Grading the severity of congestive heart failure in infants显示文摘 | Ross RD Bollinger RO Pinsky WW | 1992 | Pediatr Cardiol1992，13，2： | 1 |
| 12 | Use of the Syrian hamster as a new model of Ebola virus disease and other viral hem- orrhagic fevers显示文摘 | Wahl-Jensen Y Bollinger L Safronetz D | 2012 | Viruses2012，4，12： | 1 |
| 13 | Meaning and Memory显示文摘 | Bollinger D | 1976 | Forum Linguis- ticum1976，，1： | 1 |
| 14 | Cradle-to-cradle design: Creating healthy emissions e a strategy for eco-effective product and system design 显示文摘 | Braungart M McDonough W Bollinger A | 2007 | Journal of Cleaner Production2007，，15： | 1 |
| 15 | Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination显示文摘 | Lole K S Bollinger R C Paranjape R S Novak N G | 1999 | J Virol1999，73，： | 1 |
| 16 | Rapid, Nonmechanical, Damage-free of Optical Surface Using Plasma Assisted Etch- ing (PACE) 显示文摘 | David Bollinger L Charles B Zarowin | 1998 | SPIE : Advanced Optical Manufacturing and Testing1998，，966： | 1 |
| 17 | Adsorption of diuron and its degradation products from aqueous solution by surfactant- modified pillared clays 显示文摘 | Bouras O Bollinger J C Baudu M | 2007 | Applied Clay Science2007，37，34： | 1 |
| 18 | Viable but nonculturable bacteria are present in mouse and human urine specimens显示文摘 | Anderson M Bollinger D Hagler A | 2004 | J Clinmicrobiol2004，42，2： | 1 |
| 19 | Calcium carbonate solubility:a Reappraisal of scale formation and inhibition显示文摘 | Jean-Yves Gal Jean-Claude Bollinger Henri Tolosa | 1996 | Talanta1996，43，： | 1 |
| 20 | Heavy metals desorption from synthesized and natural iron and manganese oxyhydroxides: effect of reduction conditions显示文摘 | Davranche M Bollinger J C | 2000 | Journal of Colloid and In- terface Science2000，227，： | 1 |
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