|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 根治性手术与短程放疗后行经肛门内镜显微手术(TEM)保留器官治疗早期直肠癌(TREC):一项随机、开放标签的可行性研究显示文摘背景:基于全直肠系膜切除(total mesorectal excision,TME)的根治性手术可能不是早期直肠癌的最佳一线治疗。选择性TME保留器官的策略可以减少治疗的不良反应,又不会显著影响肿瘤结果。该临床随机研究通过与TME比较,探讨器官保留策略的可行性。方法:TREC是一项在英国21个三级转诊中心进行的随机、开放标签的可行性研究。符合条件的受试者年龄≥18岁,分期为T2期或更早,最大直径不超过30 mm;排除淋巴结受累或转移的患者。患者按计算机随机分配(1:1)接受短程放疗保留器官,8~10周后行经肛门内镜显微手术(transanal endo⁃scopic microsurgery,TEM)或TME术。当TEM标本组织病理学特征提示局部复发风险增加时,患者被考虑计划早期转为TME。一项非随机前瞻性登记收集了认为不适合随机化的患者,因为每例患者都是按临床指征治疗的。主要终点为12、18和24个月的累积随机分组。次要结局为应用欧洲癌症研究与治疗组织(EORTC)QLQ C30和CR29量表对意向治疗人群的安全性、有效性和健康相关生活质量进行了评价。该研究已在ISRCTN注册中心注册,ISRCTN14422743。 | 佟伟华 BACH S P GILBERT A BROCK K | 2021 | 结直肠肛门外科2021，27，3： | 9 |
| 2 | Radiation environment measurements with the comic ray experiments on-board the KITSAT-1 and PoSAT-1 micro-sattellites显示文摘 | Brock D J Williams P S | 1994 | IEEE TransNuclSci1994，41，6： | 1 |
| 3 | Plasticity and reprogramming of differentiated cells in amphibian regeneration显示文摘 | Brockes J P Kumar A | 2002 | Nat Rev Mol Cell Biol2002，，3： | 1 |
| 4 | Appendage regeneration in adult vertebrates and implications for regenerative med- icine显示文摘 | Brockes J P Kumar A | 2005 | Science2005，310，： | 1 |
| 5 | Radioimmunometric assay for a monoclonal antibody-defined tumor marker,CA 19-9显示文摘 | Del Villano BC Brennan S Brock P | 1983 | Clin Chem1983，29，3： | 1 |
| 6 | Crack extension at an interface: Prediction of fracture toughness and simulation of crack path deviation显示文摘 | NEGRE P STEGLICH D BROCKS W | 2005 | International Journal of Fracture2005，134，34： | 1 |
| 7 | Endoscopic tri-modal imaging for surveillance in ulcerative colitisrandomised comparison of high-resolution endoscopy and autofluorescence imaging for neoplasia detection ; and evaluation of narrow-band imaging for classification of lesions 显示文摘 | Van den Brock FJC Fnckens P Van Eeden S | 2008 | Gut2008，57，8： | 1 |
| 8 | Doping graphene with metal contacts显示文摘 | Giovannetti G Khomyakov P Brocks G | 2008 | Plays Rev Lett2008，101，26： | 1 |
| 9 | Pain relief during oocyte retrieval exploring the role of different frequencies of electroacupuncture显示文摘 | Humaidan P Brock K Bungum L | 2006 | Reprod Biomed Online2006，13，1： | 1 |
| 10 | Measurement of soil microbial biomass provides an early indication of changes in total organic matter due to straw incorporation 显示文摘 | Powlson D S Brockes P C Christensen B T | 1987 | Soil Biology &Biochemistry1987，19，： | 1 |
| 11 | Prognostic stratification for chil- dren with hepatoblastoma: the SIOPEL experience显示文摘 | Maibach R Roebuck D Brugieres L Capra M Brock P DalPIgna P | 2012 | Eur J Cancer2012，48，： | 1 |
| 12 | Neurovascular decompression in trigeminal neuralgia: role of intraoperative neurophysiological monitoring in the learning period 显示文摘 | Brock S Scaioli V Ferroli P | 2004 | Stereotact Funct Neurosurg2004，82，56： | 1 |
| 13 | Fungicide risk assessment for aquatic ecosystems : Importance of inter specific variation, toxic mode of action, and exposure regime显示文摘 | Maltby L Brock T C M Van den Brink P J | 2009 | Environmental Science & Technology2009，43，19： | 1 |
| 14 | Hepatic ablation using radiofrequency electrocautery显示文摘 | mc GAHAN J P BROWNING P D BROCK J M | 1990 | Invest Radiol1990，25，3： | 1 |
| 15 | Sweating responses during heat acclimation and moderate conditioning显示文摘 | Shvartz E Bhattacharya A Sperinde S J Brock P J Sciaraffa D Van Beaumont W | 1979 | J Appl Physiol1979，46，： | 1 |
| 16 | Pain relief during oocyte retrieval-exploring the role of different frequencies of electro- acupuncture 显示文摘 | Humaidan P Brock K Bungum L | 2006 | Reprod Biomed Online2006，13，1： | 1 |
| 17 | Understanding the behavior of bank spreads in Latin America 显示文摘 | Brock P L | 2000 | Journal of Development Economics2000，63，1： | 1 |
| 18 | HLA-DM,HLA-DO and tapasin:functional similarities and differences显示文摘 | Brocke P Carbi N Momburg F | 2002 | Curr Opin Immunol2002，14，1： | 1 |
| 19 | DNA Sequencing on a Chip 显示文摘 | Wallraff G Labadie J Brock P | 1997 | Chemtech1997，，： | 1 |
| 20 | Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3kinase gamma显示文摘 | VOIGT P BROCK C NURNBERG B | 2005 | Biol Chem2005，280，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员