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128篇 您的检索式:作者名="BROERSMA"
    题名 作者 年代 出处 被引量
1内毒素诱导大鼠葡萄膜炎的组织平片和切片研究显示文摘目的:探讨内毒素诱导的视网膜脉络膜改变和平片、切片结果的差异。方法:从内毒素注射的Lewis鼠制备视网膜和脉络膜-巩膜复合体平片以及眼组织冰冻切片,并进行免疫组织化学染色。结果:平片上显示,注射后4小时单核细胞浸润,随后,大量的单核巨噬细胞浸润至整个视网膜和脉络膜,脉络膜中尚有MHC-Ⅱ类抗原阳性细胞增多;切片上发现,于注射后一定时期,视网膜和脉络膜中有上述细胞浸润。结论:平片技术为视网膜脉络膜原发性严重受累提供了确凿的证据,内毒素诱导的葡萄膜炎可作为人类全葡萄膜炎的动物模型。杨培增 Alex F. de Vos Lidy Broersma Aize kijlstra 1996中华眼底病杂志1996,12,1:16
2实验性自身免疫性葡萄膜视网膜炎中浸润细胞的表型及其凋亡的研究显示文摘目的 探讨实验性自身免疫性葡萄膜视网膜炎 (experimental autoimmune uveoretinitis,EAU)中参与的细胞表型及其凋亡。 方法 用光感受器间维生素 A类结合蛋白 (interphotoreceptorretinoid- binding protein,IRBP)免疫 16只 L ewis鼠后 ,于眼组织切片和平片上进行免疫组织化学染色和原位凋亡染色 ,所用抗体为抗单核细胞、巨噬细胞 (EDI)、MHC- 类抗原 (OX6 )、T淋巴细胞 (R73)的单克隆抗体 ,所用原位凋亡试剂盒为 TACS1Klenow。 结果 用 IRBP免疫 L ewis鼠后 ,16只鼠中 12只发生了临床可见的葡萄膜炎 ,炎症平均得分为 1.2 9± 0 .7级 ;免疫组织化学染色发现葡萄膜和视网膜中有大量的单核细胞、淋巴细胞及 MHC- +细胞浸润 ,这些组织中均可见浸润细胞的凋亡 ,虹膜睫状体中凋亡细胞明显多于脉络膜和视网膜中的凋亡细胞。 结论 单核巨噬细胞、淋巴细胞和 MHC- +细胞均参与了 EAU的形成 ,在 EAU早期即有浸润细胞发生凋亡 ,此可能是导致这种炎症迅速消退的重要机制。杨培增 Nicole H Herzberg 周红颜 黄祥坤 谢楚芳 金浩丽 籍利 Lidy Broersma Mavc D de Smet Aize Kijlstra 2000中华眼底病杂志2000,16,1:9
3Heavy cycles in weighted graphs显示文摘Bondy J A Broersma H J Heuvel J van den 2002Discuss Math Graph Theory2002,22,:1
4Regional differences in labour productivity in the Netherlands 显示文摘Lourens Broersma Jouke Van Dijk 2005Tijdsehrift voor Economisehe en Sociale Geografie2005,96,3:1
5Application of the Firefly Algorithm for Solving the Economic Emissions Load Dispatch Problem显示文摘Theofanis Apostolopoulos Aristidis Vlachos Hajo Broersma 2010International Journal of Combinatorics2010,,:1
6Sector Structure and Cluster Economies:A Decomposition of Regional Labour Productivity显示文摘Oosterhaven J Broersma L 2007Regional Studies2007,41,:1
7A Fan type condition for heavy cycles in weighted graphs显示文摘Zhang Shenggui Broersma H J Li Xueliang 2002Graphs Combin2002,18,:1
8Aσ3 type condition for heavy cycles in weighted graphs显示文摘Zhang Shenggui Broersma H J Li Xueliang 2001Discuss Math Graph Theory2001,21,:1
9The influence of high molecular weight sodium hyaluronate on the production of migration inhibitory fact显示文摘Gacey R Broersma L Koomeet L 1987Curr Eye Res1987,6,:1
10Combined diffusion, adsorption, and reaction studies of n-hexane hydroisomerization over Pt/H- mordenite in an oscillating microbalance 显示文摘VAN DONK S BROERSMA A GIGZEMAN O L J etal 2001J Catal2001,204,2:1
11Remarks on hamiltonian properties of claw-free graphs显示文摘Ainouche A Broersma H J Veldman H J 1990Ars Combin1990,29,:1
12Combined diffusion,adsorption,and reaction studies of n-hexane hydroisomerization over Pt/H-mordenite in an oscillating microbalance显示文摘Van Donk S Broersma A Gijzeman O L J 2001J Catal2001,204,:1
13The Hamiltonian index of a graph and its branch-bonds 显示文摘Xiong Liming Broersma H J Li Xueliang 2004Discrete Math2004,285,123:1
14PIV measurements and CFD computations of secondary flow in a centrifugal pump impeller 显示文摘Westra R W Broersma L Van Andel 2010Journal of Fluids Engineering2010,132,06:1
15Stars and bunches in planar graphs(part Ⅱ):general planar graphs and colorings显示文摘Borodin O V Broersma H J Glebov A 2001Diskret Anal Issled Oper Ser 12001,8,:1
16PIV measurements and CFD computations of secondary flow in a centrifugal pump impeller 显示文摘WESTRA R W BROERSMA L VAN Andel K 2010Journal of flui- ds engineering2010,132,6:1
17The effect of thrombin inhibition in a rat arterial thrombosis model显示文摘Broersma R J Kutcher L W Heminger E F 1991Thromb Res1991,64,4:1
18Plant species diversity and soil quality in harvested and grazed boreal aspen stands of northeastern British columbia显示文摘KRZIC M NEWMAN R F BROERSMA K 2003Forest Ecology and Management2003,182,:1
19Effect of macrophage depletion on immune effector mechanisms during corneal allograft rejection in rats显示文摘Slegers TPAM Torres PF Broersma L Van Rooijen N Van Rij G Vander Gaag R 2000Invest Ophthalmol Vis Sci2000,41,8:1
20Effect of macrophage depletion on inunune ef- lector mechanisms during corneal allograft rejection in rats 显示文摘Slegers TP Torres PF Broersma L Van Rooijen N Van Rij G Van Der Gaag R 2000Invest Ophthalmol Vis Sci2000,41,8:1
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