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| 1 | Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry显示文摘AIM: To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC. METHODS: Epidemiologic, clinical, and follow-up data were obtained from the Colon Cancer Family Registry (Colon CFR). IBD-associated cases were identified from self-report of physician diagnosis. For a subset of participants, medical records were examined to confirm self-report of IBD. Cox proportional hazards regression was applied to estimate adjusted hazard ratios (aHR) and 95%CI of mortality, comparing IBD-associated to non-IBD-associated CRC, adjusted for age at CRC diagnosis, sex, Colon CFR phase, and number of prior endoscopies. Following imputation to complete CRC stage information, adjustment for CRC stage was examined. RESULTS: A total of 7202 CRC cases, including 250 cases of IBD-associated CRC, were analyzed. Over a twelve year follow-up period following CRC diagnosis, 2013 and 74 deaths occurred among non-IBD associated CRC and IBD-associated CRC patients, respectively. The difference in survival between IBD-associated and non-IBD CRC cases was not statistically significant (aHR = 1.08; 95%CI: 0.85-1.36). However, the assumption of proportional hazards necessary for valid inference from Cox regression was not met over the entire follow-up period, and we therefore limited analyses to within five years after CRC diagnosis when the assumption of proportional hazards was met. Over this period, there was evidence of worse prognosis for IBD-associated CRC (aHR = 1.36; 95%CI: 1.05-1.76). Results were similar when adjusted for CRC stage, or restricted to IBD confirmed in medical records. CONCLUSION: These results support the hypothesis that IBD-associated CRC has a worse prognosis than non-IBD-associated CRC. | Scott V Adams Dennis J Ahnen John A Baron Peter T Campbell Steven Gallinger William M Grady Loic LeMarchand Noralane M Lindor John D Potter Polly A Newcomb | 2013 | World Journal of Gastroenterology2013，19，21： | 2 |
| 2 | Cytokines,inflammation and brain injury:role of tumor necrosis factor-α显示文摘 | Feuerstein GZ Liu T Barone FC | 1994 | Cerebrovasc Brain Metab Rev1994，6，： | 2 |
| 3 | Medical complications of surgical treatment of adult spinal deformity and how to avoid them显示文摘 | Baron E M Albert T J | 2006 | Spine2006，31，19： | 1 |
| 4 | Bacteria and viruses induce production of interferon in the cerebrospinal fluid of children with acute meningitis: a study of 57 cases and review显示文摘 | Chonmaitree T Baron S | 1991 | Rev Infect Dis1991，13，6： | 1 |
| 5 | Pancreaticobiliary and duode- nal perforations after periampullary endoscopic proce- dures : diagnosis and management显示文摘 | Fatima J Baron T H Topazian M D Houghton S G Iqbal C W Ott B J | 2007 | Arch Surg2007，142，： | 1 |
| 6 | Quality indicators for colonoscopy显示文摘 | REX D K PETRINI J L BARON T H | 2006 | Am J Gastroenterol2006，101，4： | 1 |
| 7 | ASGE guideline:Colorectal cancer screening and surveillance显示文摘 | Davila R E Rajan E Baron T H | 2006 | Gastrointest Endosc2006，63，4： | 1 |
| 8 | 显示文摘 | Le Baron PC Wang Z Pinnavaia T | 1999 | J Appl Clay Sci1999，15，12： | 1 |
| 9 | Does chronic atrial fibrillation induce cardiac remodeling? 显示文摘 | Fuchs T Baron EL Leitman M | 2013 | Echocardiography2013，30，： | 1 |
| 10 | Severe bradycardia during scalp nerve block in patient undergoing awake craniotomy 显示文摘 | Chowdhury T Baron K Cappellani RB | 2013 | Saudi J Anaesth2013，7，3： | 1 |
| 11 | ASGE guideline: The role of ERCP in diseases of the biliary tract and the pancreas显示文摘 | Adler D G Baron T H Davila R E | 2005 | Gastrointestinal Endoscopy2005，62，1： | 1 |
| 12 | Pancreat- icobiliary and duodenal perforations after periampullary endo- scopic procedures: diagnosis and management 显示文摘 | FATIMA J BARON T H TOPAZIAN M D | 2007 | Arch Surg2007，142，5： | 1 |
| 13 | Rescue of rinderpest virus from cloned cDNA显示文摘 | BARON M D BARRETT T | 1997 | J Virol1997，71，2： | 1 |
| 14 | An enzyme linked immunosorbent assay (ELISA) for the detection of antibodies to the porcine reproductive and respiratory syndrome (PRRS) virus 显示文摘 | Albina E Leforban Y Baron T | 1992 | Ann Rech Vet1992，23，3： | 1 |
| 15 | Acute necorotizing pancreaatilis显示文摘 | Baron T Morgan DE | 1999 | N Eng J Med1999，340，18： | 1 |
| 16 | Ethanol blend effects on direct injection spark-ignition gasoline vehicle particulate matter emissions显示文摘 | STOREY J BARONE T NORMAN K | 2010 | SAE International Journal of Engines2010，3，2： | 1 |
| 17 | Endoscopic papillary large-balloon dilation combined with endoscopic biliary sphincterotomy for the removal of bile duct stones显示文摘 | MEINE G C BARON T H | 2011 | Gastrointest Endosc2011，74，9： | 1 |
| 18 | Distinct and sequential up-regulation of genes regulating cell growth and cell cycle progression during hepatic ischemia-reperfusion injury显示文摘 | Barone S Okaya T Rudich S | 2005 | Am J Physiol Cell Physiol2005，289，4： | 1 |
| 19 | Diffaction of a Pressure Wave by a Cylindrical Cavity in an Elastic Medium显示文摘 | Baron M L Mattews A T | 1961 | Journal of Applied Mechanics1961，28，3： | 1 |
| 20 | Cloning and sequence analysis of the matrixprotein gene of rinderpest virus and evidence for another bovine morbillivirus显示文摘 | Baron M D Goatley L Barrett T | 1994 | Virology1994，200，1： | 1 |
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