|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis显示文摘Background There is concern that blood pressure(BP)lowering in acute stroke may compromise cerebral perfusion and worsen outcome in the presence of carotid stenosis.We assessed the effect of glyceryl trinitrate(GTN)in patients with carotid stenosis using data from the Efficacy of Nitric Oxide in Stroke(ENOS)Trial.Methods ENOS randomised 4011 patients with acute stroke and raised systolic BP(140-220 mm Hg)to transdermal GTN or no GTN within 48 hours of onset.Those on prestroke antihypertensives were also randomised to stop or continue their medication for 7 days.The primary outcome was the modified Rankin Scale(mRS)at day 90.Ipsilateral carotid stenosis was split:<30%;30-<50%;50-<70%;≥70%.Data are ORs with 95%CIs adjusted for baseline prognostic factors.results 2023(60.5%)ischaemic stroke participants had carotid imaging.As compared with<30%,≥70%ipsilateral stenosis was associated with an unfavourable shift in mRS(worse outcome)at 90 days(OR 1.88,95%CI 1.44 to 2.44,p<0.001).Those with≥70%stenosis who received GTN versus no GTN had a favourable shift in mRS(OR 0.56,95%CI 0.34 to 0.93,p=0.024).In those with 50-<70%stenosis,continuing versus stopping prestroke antihypertensives was associated with worse disability,mood,quality of life and cognition at 90 days.Clinical outcomes did not differ across bilateral stenosis groups.Conclusions Following ischaemic stroke,severe ipsilateral carotid stenosis is associated with worse functional outcome at 90 days.GTN appears safe in ipsilateral or bilateral carotid stenosis,and might improve outcome in severe ipsilateral carotid stenosis. | Jason P Appleton Lisa J Woodhouse Andrew Belcher Daniel Bereczki Eivind Berge Valeria Caso Hui Meng Chang Hanne K Christensen Ronan Collins John Gommans Ann C Laska George Ntaios Serefnur Ozturk Gillian M Sare Szabolcs Szatmari Yongjun Wang Joanna M Wardlaw Nikola Sprigg Philip M Bath for the ENOS investigators | 2019 | Stroke & Vascular Neurology2019，4，1： | 6 |
| 2 | Metformin in patients with non-alcoholic fatty liver disease: A randomized, controlled trial显示文摘 | John Willy Haukeland Zbigniew Konopski Heidi Beate Eggesb? Hilde L?land von Volkmann Gabriele Raschpichler Kristian Bj?ro Terese Haaland Else Marit L?berg K?re Birkeland | 2009 | Scandinavian Journal of Gastroenterology2009，，7： | 3 |
| 3 | Loss of MeCP2 in cholinergic neurons causes part of RTT- like phenotypes via α7 receptor in hippocampus显示文摘 | Ying Zhang Shu-Xia Cao Peng Sun Hai-Yang He Ci-Hang Yang Xiao-Juan Chen Chen-Jie Shen Xiao-Dong Wang Zhong Chen Darwin K Berg Shumin Duan Xiao-Ming Li | 2016 | Cell Research2016，26，6： | 3 |
| 4 | Submicron and ultrafine grained hardmetals for microdrills and metal cutting inserts显示文摘 | G Gille B Szesny K Dreyer H van den Berg J Schmidt T Gestrich G Leitner | 2002 | International Journal of Refractory Metals and Hard Materials2002，，1： | 2 |
| 5 | Farming options for the Netherlands explored by multi-objective modeling 显示文摘 | TEN BERGE H F M VAN ITYERSUM M K ROSSING W A H | 2000 | Eur J Agron2000，13，23： | 1 |
| 6 | A new serum type system in man - the Lp system显示文摘 | | 1963 | Acta pathol Microbiol Scand1963，59，： | 1 |
| 7 | Cis-l,4-poly-β-myrcene: The structure of the polymeric fraction of mastic resin elucidated显示文摘 | Berg K J Horst J Boon J J | 1998 | TetrahedronLetters1998，39，： | 1 |
| 8 | Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill显示文摘 | Hansen MB Nielsen SE Berg K | 1989 | J Immunol Method1989，119，： | 1 |
| 9 | Use of 5-ALAesters to improve photodynamic therapy on cells显示文摘 | Gaullier J Berg K | 1997 | J Cancer Res Clinical Oncology1997，57，： | 1 |
| 10 | Normal FHIT transcripts in renal cell cancer and lung cancer-drived cell lines, including a cell line with a homozygous deletion in the FRA3B region显示文摘 | Van den Berg A Draaijers TG Kok K | 1997 | Genes Chromosomes cancer1997，19，2： | 1 |
| 11 | Re- examination and further development of a precise and rapid dye method for measuring cell growth/cell kill显示文摘 | Hansen MB Nielsen SE Berg K | 1989 | J Immunol Methods1989，119，： | 1 |
| 12 | Near-net-shaping in the hardmetal industry 显示文摘 | K R?diger H van den Berg K Dreyer | 2002 | Refractory Metals & Hard Materials2002，18，23： | 1 |
| 13 | 5-Aminolevulinic acid-based photodynamic therapy:Clinical research and future challenges显示文摘 | PENG Q WARLOE T BERG K | 1997 | Cancer1997，79，12： | 1 |
| 14 | Dynamie and static lung volumes of school children with cerebral palsy显示文摘 | Bjure J Berg K | 1920 | Acta Paediatr Scand1920，204，： | 1 |
| 15 | Diversity and antagonistic potential of bacteria associated with bryophytes from nutrient-poor habitats of the Baltic Sea Coast显示文摘 | Opelt K Berg G | 2004 | Applied and Environmental Microbiology2004，70，： | 1 |
| 16 | DOING THERAPY: A POST-STRUCTURAL RE-VlSION显示文摘 | Shazer S Berg I K | 1992 | Journal of Marital and Family Therapy1992，18，1： | 1 |
| 17 | Medical students' self-reported empathy and simulated patients' assessments of student empathy:an analysis by gender and ethnicity显示文摘 | Berg K Majdan JF Berg D | 2011 | Acad Med2011，86，8： | 1 |
| 18 | Cyclic reproduction, sex determination and depression in the Cladocera显示文摘 | BERG K | 1934 | Biological Review1934，9，： | 1 |
| 19 | Doing therapy: A post-structural revision显示文摘 | De SHAZER S BERG I K | 1992 | J Marital Family Therapy1992，18，： | 1 |
| 20 | 5-Aminolevulinic acid-based photodynamic therapy: principles and experimental research 显示文摘 | Peng Q Berg K Moan J | 1997 | Photoehem Photobiol1997，65，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员