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| 1 | Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar. | Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 6 |
| 2 | Cognitive status of Bsychiat- ric patients under maintenance electroconvulsive therapy: a one - year longitudinal study 显示文摘 | Rami L Bernardo M Boget T | 2004 | J Neuropsychiatry Clin Heurosci2004，16，4： | 1 |
| 3 | Bifurcations in non-smooth dynamical systems显示文摘 | di Bernardo M Budd C Champneys A R Kowalczyk P Nordmark A B Olivvar G Piiroinen P T | 2008 | SIAM Review2008，50，4： | 1 |
| 4 | MRI of localized prostate cancer:coming of age in the PSA era显示文摘 | Tüirkbey B Bernardo M Merino M J | | 0，，1： | 1 |
| 5 | MRI of tumor angiogenesis显示文摘 | Barrett T Brechbiel M Bernardo M Choyke P L | 2007 | J Magn Reson Imaging2007，26，： | 1 |
| 6 | Reaction Pathways in the Solid State Synthesis of Multiferroic BiFeO3 显示文摘 | Bernardo M S Jardiel T Peiteado Mf | 2011 | Journal of the European Ceramic Society2011，31，16： | 1 |
| 7 | Cognitive status of psychiatric patients under maintenance electroconvulsive therapy: a one-year longitudinal study显示文摘 | Rami L Bernardo M Boget T | 2004 | J Neuropsychiatry Clin Neurosci2004，16，4： | 1 |
| 8 | MRI of tumor angiogenesis显示文摘 | Barrett T Brechbiel M Bernardo M | 2007 | J Magn Reson Imaging2007，26，： | 1 |
| 9 | Generic bifurcations of low codimension of planar Filippov systems显示文摘 | Bernardo M D Seara T M Teixeira M A | 2011 | Differential Equations2011，250，4： | 1 |
| 10 | A Review of Antarctic Surface Snow Isotopic Composition: Observations, Atmospheric Circulation, and Isotopic Modeling*显示文摘 | Masson-Delmotte V Hou S Ekaykin A Jouzel J Aristarain A Bernardo R T Bromwich D Cattani O Delmotte M Falourd S Frezzotti M Gallée H Genoni L Isaksson E Landais A Helsen M M Hoffmann G Lopez J Morgan V Motoyama H Noone D Oerter H Peti | 2008 | Journal of Climate2008，，13： | 1 |
| 11 | MRI of tumor angiogenesis显示文摘 | Barrett T Brechbiel M Bernardo M | 2007 | J Magn Reson Imaging2007，26，2： | 1 |
| 12 | MRI of tumor angiogenesis显示文摘 | Barrett T Brechbiel M Bernardo M | 2007 | J Magn Reson Imaging2007，26，2： | 1 |
| 13 | MRI of tumor angiogenesis 显示文摘 | BARRETT T BRECHBIEL M BERNARDO M | 2007 | J Magn Reson Imaging2007，26，2： | 1 |
| 14 | MRI of tumor angiogenesis显示文摘 | Barrett T Brechbiel M Bernardo M | 2007 | J Magn Reson Imaging2007，26，2： | 1 |
| 15 | Intravenous ferric carboxymaltose versus standard medical care in the treatment of iron deficiency anemia in patients with chronic kidney disease:a randomized,active-controlled,multi-center study显示文摘 | Charytan C Bernardo M V Koch T A | 2013 | Nephrol Dial Transplant2013，28，4： | 1 |
| 16 | A general multivariate Bayesian process capability index 显示文摘 | Bernardo J M Irony T Z | 1996 | The Statistician1996，45，4： | 1 |
| 17 | Sub types of memory dysfunction associated with ECT= charac teristics and neurobiological bases 显示文摘 | Rami Conzalez L Bernardo M Boget T | 2001 | J ECT2001，17，2： | 1 |
| 18 | Cognitive status of psychiatric patients under maintenance electroconvulsive therapy:a one-year longitudinal study显示文摘 | Rami L Bernardo M Boget T | 2004 | J Neuropsychiatry Clin Neurosci2004，16，4： | 1 |
| 19 | Does nesiritide reduce mortality and readmission in decompensated heart failure 显示文摘 | Bernardo W M Moreira F T | 2012 | Rev Assoc Med Bras2012，58，2： | 1 |
| 20 | MRI of tumor angiogenesis显示文摘 | Barrett T Brechbiel M Bernardo M | 2007 | J Magn Reson Imaging2007，26，2： | 1 |
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