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| 1 | Acute renal injury after partial hepatectomy显示文摘Currently, partial hepatectomy is the treatment of choice for a wide variety of liver and biliary conditions. Among the possible complications of partial hepatectomy, acute kidney injury(AKI) should be considered as an important cause of increased morbidity and postoperative mortality. Difficulties in the data analysis related to postoperative AKI after liver resections are mainly due to the multiplicity of factors to be considered in the surgical patients, moreover, there is no consensus of the exact definition of AKI after liver resection in the literature, which hampers comparison and analysis of the scarce data published on the subject. Despite this multiplicity of risk factors for postoperative AKI after partial hepatectomy, there are main factors that clearly contribute to its occurrence. First factor relates to large blood losses with renal hypoperfusion during the operation, second factor relates to the occurrence of post-hepatectomy liver failure with consequent distributive circulatory changes and hepatorenal syndrome. Eventually, patients can have more than one factor contributing to post-operative AKI, and frequently these combinations of acute insults can be aggravated by sepsis or exposure to nephrotoxic drugs. | Luis Alberto Batista Peres Luis Cesar Bredt Raphael Flavio Fachini Cipriani | 2016 | World Journal of Hepatology2016，8，21： | 3 |
| 2 | Risk factors for acute kidney injury after partial hepatectomy显示文摘AIM To identify risk factors for the occurrence of acute kidney injury(AKI) in the postoperative period of partial hepatectomies. METHODS Retrospective analysis of 446 consecutive resections in 405 patients, analyzing clinical characteristics, preoperative laboratory data, intraoperative data, and postoperative laboratory data and clinical evolution. Adopting the International Club of Ascites criteria for the definition of AKI, potential predictors of AKI by logistic regression were identified. RESULTS Of the total 446 partial liver resections, postoperative AKI occurred in 80 cases(17.9%). Identified predictors of AKI were: Non-dialytic chronic kidney injury(CKI), biliary obstruction, the Model for End-Stage Liver Disease(MELD) score, the extent of hepatic resection, the occurrence of intraoperative hemodynamic instability, post-hepatectomy haemorrhage, and postoperative sepsis. CONCLUSION The MELD score, the presence of non-dialytic CKIand biliary obstruction in the preoperative period, and perioperative hemodynamics instability, bleeding, and sepsis are risk factors for the occurrence of AKI in patients that underwent partial hepatectomy. | Luis Cesar Bredt Luis Alberto Batista Peres | 2017 | World Journal of Hepatology2017，9，18： | 2 |
| 3 | Biological roles of nitric oxide显示文摘 | Snyder SH Bredt DS | 1992 | Sci Am1992，266，5： | 1 |
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| 7 | 临港新城——中国航海博物馆 意象与隐喻显示文摘航海博物馆的单体建筑使用统一的形式和材质语言构筑了一个均质匀称的整体。柱廊和空梁是微妙的造型元素,配合光和影的错综变幻,加上水面和绿地,将建筑群系结为一个整体。两座高58m的交叠轻质屋面壳体表现了关于航海的隐喻,使人联想起风帆,两面风帆交于地面以上40m处的一点。而每面风帆在地面上仅各有两个支点。风帆之间通过巨型索网结构找形.由玻璃幕墙封闭,从而围拢形成为一座充满张力中空展厅.其内可陈列大型古代船舶摆件供人们鉴赏。相互交错对峙的“风帆”悬浮般地立于建筑裙楼之上,成为整个博物馆建筑重要而富表现力的主题形象,从而刻画了临港新城的城市天际线。 | 曼哈德.冯.格康 Hans Georg Esch Jan Siefke Marcus Bredt | 2013 | 城市环境设计2013，，7： | 1 |
| 8 | Nitric oxide in skeletal muscle显示文摘 | Kobzik L Reid M B Bredt D S | 1994 | Nature1994，372，6506： | 1 |
| 9 | Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain andperipheral tissues显示文摘 | Dawson TM Bredt DS Fotuhi M Hwang PM Snyder SH | 1991 | Proc Natl Acad Sci USA1991，88，17： | 1 |
| 10 | Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues 显示文摘 | Dawson TM Bredt DS Fotuhi M | 1991 | Proc Natl Acad Sci USA1991，88，17： | 1 |
| 11 | Postsynaptic density-95mimics and occludes hippocampal long-term potentiation and enhances long-term depression显示文摘 | Stein V House DR Bredt DS | 2003 | J Neurosci2003，23，13： | 1 |
| 12 | Nitric oxide synthase and neuronal NADPH-disphorase are indentical in brain and peripheral tissuse显示文摘 | Dawson T W Bredt D S Fotuhi M | 1991 | Proc Natl Acad Sci USA1991，88，17： | 1 |
| 13 | Comparative genomic hybridization(CGH) and fluorescence in situ hybridization(FISH) in the diagnosis of hepatocellular cancinoma显示文摘 | Wilkens L Bredt M Fleing P | 2002 | J Hepatobiliary Pancreat Surg2002，9，： | 1 |
| 14 | Nitric oxide as a neuronal messenger显示文摘 | Bredt DS | 1991 | Trends Pharmacol Sci1991，12，4： | 1 |
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| 16 | Kritische Bemerkungen zur drehungselastizitat 显示文摘 | Bredt R | | Zeitschrift des Vereines Deutscher Ingenieure0，40，28： | 1 |
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| 18 | Regula- tion of dendritic branching and filopodia formation in hip- pocampal neurons by specific acylated protein motifs显示文摘 | Gauthier-Campbell C Bredt DS Murphy TH | 2004 | Mol Biol Cell2004，15，5： | 1 |
| 19 | Nitric oxide in skeletal muscle显示文摘 | Kobzik L Reid MB Bredt DS | 1994 | Nature1994，372，6506： | 1 |
| 20 | Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues 显示文摘 | Bredt DS Fotuhi M | 1991 | Proc Natl Acad Sci USA1991，88，17： | 1 |
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