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151篇 您的检索式:作者名="Brian Smith"
    题名 作者 年代 出处 被引量
1Endoscopic retrograde cholangiography for pediatric choledocholithiasis: Assessing the need for endoscopic intervention显示文摘AIM:To assess pediatric patients for choledocholithiasis.We applied current adult guidelines to identify predictivefactors in children.METHODS:A single-center retrospective analysis was performed at a tertiary children's hospital.We evaluated 44 consecutive pediatric patients who underwent endoscopic retrograde cholangiography(ERCP) for suspected choledocholithiasis.Patients were stratified into those with common bile duct stones(CBDS) at ERCP vs those that did not using the American Society of Gastrointestinal Endoscopy(ASGE) guidelines(Very Strong and Strong criteria) for suspected CBDS.RESULTS:CBDS were identified in 84% at the time of ERCP.Abdominal ultrasound identified CBDS in 36% of patients.Conjugated bilirubin ≥ 0.5 mg/d L was an independent risk factor for CBDS(P = 0.003).The Very Strong(59.5%) and Strong(48.6%) ASGE criteria identified the majority of patients(P = 0.0001).A modified score using conjugated bilirubin had a higher sensitivity(81.2% vs 59.5%) and more likely to identify a stone than the standard criteria,odds ratio of 25.7 compared to 8.8.Alanine aminotransferase and gamma-glutamyl transferase values identified significant differences in a subset of patients with odds ratio of 4.1 and 3.25,respectively.CONCLUSION:Current adult guidelines identified the majority of pediatric patients with CBDS,but specific pediatric guidelines may improve detection,thus decreasing risks and unnecessary procedures.Douglas S Fishman Bruno P Chumpitazi Isaac Raijman Cynthia Man-Wai Tsai E O’Brian Smith Mark V Mazziotti Mark A Gilger 2016World Journal of Gastrointestinal Endoscopy2016,8,11:6
2The barren stalk2 Gene Is Required for Axillary Meristem Development in Maize显示文摘The diversity of plant architecture is determined by axillary meristems (AMs). AMs are produced from small groups of stem cells in the axils of leaf primordia and generate vegetative branches and reproductive inflorescences . Previous studies identified genes critical for AM development that function in auxin biosynthesis, transport, and signaling. barren stalkl (ba1), a basic helix-loop-helix transcription factor, acts downstream of auxin to control AM formation. Here, we report the cloning and characterization of barren stalk2 (ba2), a mutant that fails to produce ears and has fewer branches and spikelets in the tassel, indicating that ba2 functions in reproductive AM development. Furthermore, the ba2 mutation suppresses tiller growth in the teosinte branchedl mutant, indicating that ba2 also plays an essential role in vegetative AM development. The ba2 gene encodes a protein that co-localizes and heterodimerizes with BA1 in the nucleus . Characterization of the genetic interaction between ba2 and ba1 demonstrates that ba1 shows a gene dosage effect in ba2 mutants, providing further evidence that BA1 and BA2 act together in the same pathway. Characterization of the molecular and genetic interaction between ba2 and additional genes required for the regulation of ba1 further supports this finding. The ba1 and ba2 genes are orthologs of rice genes, LAX PANICLE1 (LAX1) and LAX2, respectively, hence providing insights into pathways controlling AMs development in grasses.Hong Yao Andrea Skirpan Brian Wardell Michaela S.Matthes Norman B.Best Tyler McCubbin Amanda Durbak Taylor Smith Simon Malcomber Paula McSteen 2019Molecular Plant2019,12,3:4
3Comparison of parametric and nonparametric models for traffic flow forecasting显示文摘Brian L Smith Billy M Williams R Keith Oswald 2002Transportation Research Part C2002,,4:3
4Traffic Flow Forecasting: Comparison of Modeling Approaches显示文摘Brian L. Smith Michael J. Demetsky 1997Journal of Transportation Engineering1997,,4:3
5S.T.O.N.E. Nephrolithometry: Novel Surgical Classification System for Kidney Calculi显示文摘Zhamshid Okhunov Justin I. Friedlander Arvin K. George Brian D. Duty Daniel M. Moreira Arun K. Srinivasan Joel Hillelsohn Arthur D. Smith Zeph Okeke 2013Urology2013,,6:2
6ECT2 and RASAL2 Mediate Mesenchymal-Amoeboid Transition In Human Astrocytoma Cells显示文摘Adrienne Weeks Nadia Okolowsky Brian Golbourn Stacey Ivanchuk Christian Smith James T. Rutka 2012The American Journal of Pathology2012,,2:2
7Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function显示文摘Lin Chen Simon N. Willis Andrew Wei Brian J. Smith Jamie I. Fletcher Mark G. Hinds Peter M. Colman Catherine L. Day Jerry M. Adams David C.S. Huang 2005Molecular Cell2005,,3:2
8The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years显示文摘Mark R Nelson Christine Katlama Julio S Montaner David A Cooper Brian Gazzard Bonaventura Clotet Adriano Lazzarin Knud Schewe Joep Lange Christina Wyatt Sue Curtis Shan-Shan Chen Stephen Smith Norbert Bischofberger James F Rooney 2007AIDS2007,,10:2
9Optical Coherence Tomographic Patterns of Diabetic Macular Edema显示文摘Brian Y. Kim Scott D. Smith Peter K. Kaiser 2006American Journal of Ophthalmology2006,,3:2
10Soluble TNF-α receptor 1 and IL-6 plasma levels in humans subjected to the sleep deprivation model of spaceflight显示文摘William T. Shearer James M. Reuben Janet M. Mullington Nicholas J. Price Bang-Ning Lee E.O’Brian Smith Martin P. Szuba Hans P.A. Van Dongen David F. Dinges 2001The Journal of Allergy and Clinical Immunology2001,,1:2
11Physical activity and nutrition attitudes in obese Hispanic children with non-alcoholic steatohepatitis显示文摘AIM:To assess nutrition,physical activity and health-ful knowledge in obese children with biopsy-proven nonalcoholic steatohepatitis(NASH or NA)compared to children without liver disease.METHODS:Children with biopsy-proven NASH comprised the NASH group.Age,sex and ethnicity matched control groups consisted of obese(OB)and lean(CO) children with no liver disease.Subjects were adminis-tered the School Physical Activity and Nutrition Survey and one blood draw was obtained.RESULTS:Fifty-seven patients were enrolled with a mean age of 12.1±2.1 years,and all were Hispanic.Even though the OB and NA had a similar increased body mass index(%),35%of the NA group always read nutrition labels compared to none in the OB(P<0.05),and more NA children felt their diet is'less healthy'.NA consumed the least amount of fruits with only 25%having≥1 fruit/d vs 45%in OB and 64.7% in CO(P<0.05 NA vs CO).Only 15%of NA subjects performed light exercise vs 35%and 59%of OB and CO groups,respectively(P=0.02).The mean physical activity score was lowest in the NA group(P<0.05).Amongst the subjects with NASH,we found that 100% of patients with grade 2 or 3 fibrosis had a sedentary score>2 compared to only 63.6%of those with grade 1 or no fibrosis(P<0.05).CONCLUSION:Children with NASH had increased sedentary behavior,decreased activity,and fruit intake.Larger studies may determine the benefit of changing these behaviors as treatment for NASH.Lana N Hattar Theresa A Wilson Leanel A Tabotabo E O'Brian Smith Stephanie H Abrams 2011World Journal of Gastroenterology2011,17,39:2
12Comparison of parametric and nonparametric models显示文摘Brian L Smith Billy M Williams R Keith Oswald 2002Transportation Research Part C2002,,10:1
13Comparison of parametric and nonparametric models for traffic flow forecasting显示文摘Brian L Smith Billy M Williams and R Keith Oswald 2002Transportation Research Part C: Emerging Technologies2002,10,4:1
14Assessment of CFD Codes used in nuclear reactor safety simulations显示文摘Smith Brian L 2010Nuclear Engineering and Technology2010,42,4:1
15The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33显示文摘Gaby Palmer Brian P. Lipsky Molly D. Smithgall David Meininger Sophia Siu Dominique Talabot-Ayer Cem Gabay Dirk E. Smith 2008Cytokine2008,,3:1
16Management Succession and Financial Performance of Family Controlled Firms显示文摘Brian F Smith Ben A 1999Journal of Corporate Finance1999,,:1
17A Novel Monoclonal Antibody Against DOG1 is a Sensitive and Specific Marker for Gastrointestinal Stromal Tumors显示文摘Inigo Espinosa Cheng-Han Lee Mi Kyung Kim Bich-Tien Rouse Subbaya Subramanian Kelli Montgomery Sushama Varma Christopher L. Corless Michael C. Heinrich Kevin S. Smith Zhong Wang Brian Rubin Torsten O. Nielsen Robert S. Seitz Douglas T. Ross Robert B. West 2008The American Journal of Surgical Pathology2008,,2:1
18Enhanced localized computerized tomography employing the discrete wavelet transform 显示文摘Smith Brian J Adhami Reza R 2000Circuits Systems and Signal Processing2000,19,5:1
19Prospective study of a laparoscopically placed adjustable gastric band in the treatment of morbid obesity显示文摘O' Brian P Brown W Smith A 1999Br J Surg1999,86,1:1
20Quantitation of echocardographic predictors of out - come in infants with isolated Ventricular Septal de- fect显示文摘Shirali GS Smith O Brian Geva T 1995Am Heart J1995,130,:1
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