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| 1 | Assessment of vascular invasion in gastric cancer: A comparative study显示文摘AIM: To evaluate and compare detection of lymphatic and blood vessel invasion (LVI and BVI) by hematox-ylin-eosin (HE) and immunohistochemistry (IHC) in gastric cancer specimens, and to correlate with lymph node status. METHODS: IHC using D2-40 (a lymphatic endothelial marker) and CD34 (a pan-endothelial marker) was performed to study LVI and BVI in surgical specimens froma consecutive series of 95 primary gastric cancer cases. The results of the IHC study were compared with the detection by HE using McNemar test and kappa index. The morphologic features of the tumors and the presence of LVI and BVI were related to the presence of lymph node metastasis. A χ2 test was performed to obtain associations between LVI and BVI and other prognostic factors for gastric cancer. RESULTS: The detection rate of LVI was considerably higher than that of BVI. The IHC study identified eight false-positive cases and 13 false-negative cases for LVI, and 24 false-positive cases and 10 false-negative cases for BVI. The average Kappa value determined was moderate for LVI (k=0.50) and low for BVI (k=0.20). Both LVI and BVI were statistically associated with the presence of lymph node metastasis (HE: P=0.001, P=0.013, and IHC: P=0.001, P=0.019). The mor-phologic features associated with LVI were location of the tumor in the distal third of the stomach (P=0.039), Borrmann's macroscopic type (P=0.001), organ inva-sion (P=0.03) and the depth of tumor invasion (P=0.001). The presence of BVI was related only to the depth of tumor invasion (P=0.003). CONCLUSION: The immunohistochemical identification of lymphatic and blood vessels is useful for increasing the accuracy of the diagnosis of vessel invasion and for predicting lymph node metastasis. | Letícia Trivellato Gresta Ismael Alves Rodrigues-Júnior Lúcia Porto Fonseca de Castro Geovanni Dantas Cassali Mnica Maria Demas lva-res Cabral | 2013 | World Journal of Gastroenterology2013，19，24： | 8 |
| 2 | The corrosion resistance of hot dip galvanized steel pretreated with his functional silanes modified with microsiliea显示文摘 | Montemor M F Cabral A M Zheludkevich M L etal | 2006 | Surface and Coatings Technology2006，200，9： | 1 |
| 3 | Prediction of the solubility of aromatic compounds from Brazilian roasted coffee (2- methylpyrazine; 2-furfurylalcohol; 2,5-dimethylpyrazine; y-butyrolactone and 2-furfurylacetate) in SC-CO显示文摘 | DE OLIVEIRA A L EBERLIN M N CABRAL F A | 2009 | J Chem Eng Jpn2009，42，4： | 1 |
| 4 | BetaⅢ-tubulin induces pa- elitaxel resistance in association with reduced effects on microtu- bule dynamic instability 显示文摘 | Kamath K Wilson L Cabral F | 2005 | J Biol Chem2005，208，12： | 1 |
| 5 | Exercise training on disease control and quality of life in asthmatic children显示文摘 | FANELLI A CABRAL A L NEDER J A | 2007 | Med Sci Sports Exerc2007，39，： | 1 |
| 6 | Down-regulation of factor IXa in thefactor Xase complex by protein Z-dependent protease inhibitor显示文摘 | Heeb M J Cabral K M Ruan L | 2005 | JBiol Chem2005，280，33： | 1 |
| 7 | The learning curve,predation,antitrust,and welfare显示文摘 | RIORDAN M H | 1997 | The Journal of Industrial Economics1997，45，2： | 1 |
| 8 | Monopoly Pricing with Network Externalities 显示文摘 | Cabral L M B Salant D J Woroch G A | 1999 | International Journal of Industrial Organization1999，17，2： | 1 |
| 9 | Development and characterization of neutralizing monoclonal antibodies against the pandemic HIN1 virus (2009)显示文摘 | Cabral T E Berhane Y Schmidt L | 2012 | J Virol Meth2012，183，1： | 1 |
| 10 | class Ⅲ-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability显示文摘 | Kamath K Wilson L Cabral F | 2005 | J Biol Chem2005，280，12： | 1 |
| 11 | Factors associated wilh return to work following a hand injury:a qualilative/quantitalive approach显示文摘 | Cabral L H Sampaio R F Figueiredo 1 M | 2010 | Rev Bras Fisiotcr2010，14，2： | 1 |
| 12 | On the adoption of innovations with network externalities显示文摘 | Cabral L | 1990 | Mathematical Social Sciences1990，19，： | 1 |
| 13 | Changes in the cell wall and cel- lulose content of developing cotton fibers investigated by FTIR spectroscopy显示文摘 | Abidi N Cabrales L Haigler C H | 2014 | Carbohydrate Polymers2014，100，： | 1 |
| 14 | Treatment of HIV-associated multi-centric Castleman's disease with oral etoposide 显示文摘 | Scott D Cabral L Harrington WJ Jr | 2001 | Am J Hematol2001，66，2： | 1 |
| 15 | Immobilization studies of an industrial penicillin acylase preparation on a silica carrier 显示文摘 | FONSECA L P CARDOSO J P CABRAL J M S | 1993 | J Chem Technol Biotechnol1993，58，1： | 1 |
| 16 | 显示文摘 | Bueno C Cabral V F Cardozo-Filho L | 2009 | J of Supercriti- cal Fluids2009，48，2： | 1 |
| 17 | A multidimensional approach to information security risk management using FMEA and fuzzy theory显示文摘 | Maisa Mendon?a Silva Ana Paula Henriques de Gusm?o Thiago Poleto Lúcio Camara e Silva Ana Paula Cabral Seixas Costa | 2014 | International Journal of Information Management2014，，： | 1 |
| 18 | Randriamahefa catalysis of the specific michael addition: the example of acrylate acceptors 显示文摘 | Cabral J Laszlo P Montaufier S L | 1989 | Tetrahedron Lett1989，30，： | 1 |
| 19 | Beta Ⅲ-tubulin induces paclitaxel resistance in association with reduceed effects on mi- erotubule dynamic instability 显示文摘 | Kamath K Wilson L Cabral F | 2005 | Biol Chem2005，208，12： | 1 |
| 20 | Ochratoxin A in some Portuguese wines: method validation and screening in Port wine and Vinho Verde显示文摘 | Festas I Herbert P Santos L Cabral M Barros P Alves A | 2000 | American Journal of Enology and Viticulture2000，51，2： | 1 |
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