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| 1 | Procedural complexity independent of P2Y12 reaction unit(PRU)values is associated with acute in situ thrombosis in Pipeline flow diversion of cerebral aneurysms显示文摘background Acute in situ thrombosis is an ischaemic phenomenon during Pipeline embolisation device(PED)procedures with potentially high morbidity and mortality.There is controversy regarding the role of platelet function testing with P2Y12 assay as a predictor of intraprocedural thromboembolic events.There is limited knowledge on whether procedural complexity influences these events.Methods Data were collected retrospectively on 742 consecutive PED cases at a single institution.Patients with intraprocedural acute thrombosis were compared with patients without these events.results A cohort of 37 PED cases with acute in situ thrombosis(mean age 53.8 years,mean aneurysm size 8.4 mm)was matched with a cohort of 705 PED cases without intraprocedural thromboembolic events(mean age 56.4 years,mean aneurysm size 6.9 mm).All patients with in situ thrombosis received intra-arterial and/or intravenous abciximab.The two groups were evenly matched in patient demographics,previous treatment/subarachnoid hemorrhage(SAH)and aneurysm location.There was no statistical difference in postprocedural P2Y12 reaction unit(PRU)values between the two groups,with a mean of 156 in the in situ thrombosis group vs 148 in the control group(p=0.5894).Presence of cervical carotid tortuosity,high cavernous internal carotid artery grade,need for multiple PED and vasospasm were not significantly different between the two groups.The in situ thrombosis group had statistically significant longer fluoroscopy time(60.4 vs 38.4 min,p<0.0001),higher radiation exposure(3476 vs 2160 mGy,p<0.0001),higher rates of adjunctive coiling(24.3% vs 8.37%,p=0.0010)and higher utilisation of balloon angioplasty(37.8% vs 12.2%,p<0.0001).Clinically,the in situ thrombosis cohort had higher incidence of major and minor stroke,intracerebral haemorrhage and length of stay.Conclusions Predictors of procedural complexity(higher radiation exposure,longer fluoroscopy time,adjunctive coiling and need for balloon angioplasty)are associated with acute thrombotic events during PED placement,independent of PRU values. | Bowen Jiang Matthew T Bender Erick M Westbroek Jessica K Campos Li-Mei Lin Risheng Xu Rafael J Tamargo Judy Huang Geoffrey P Colby Alexander L Coon | 2018 | Stroke & Vascular Neurology2018，3，3： | 2 |
| 2 | Historical CO2 emission and concentrations due to land use change of croplands and pastures by country显示文摘 | Campos C P D Muylaert M S Rosa L P | 2005 | Science of the Total Environment2005，346，： | 1 |
| 3 | Thermal investi- gation of uncased and cased tobacco 显示文摘 | Longanezi T Campos M P A Moth6 C G | 2002 | Thermochim Ac- ta2002，39，： | 1 |
| 4 | Aunified framework for study of the anti-windup designs显示文摘 | KOTHARE M V CAMPO P J MORARI M | 1994 | Automatica1994，30，12： | 1 |
| 5 | On the Evaluation of Unsaturated Flow in a Natural Slope in Rio de Janeiro, Brazil显示文摘 | Gerscovich D M S Vargas Jr E A Campos T M P de | 2006 | Engi- neering Geology2006，88，12： | 1 |
| 6 | Dielectric behavior of Hfdoped CaCu3 Ti4 012 ceramics obtained by conventional synthesis and reactive sintering显示文摘 | Rubia M A Leret P Campo A D | 2012 | J Eur Ceram Soc2012，32，8： | 1 |
| 7 | Leptin and leptin receptor are expressed in the human endometrium and endometrial leptin secretion is regulated by the human blastocyst显示文摘 | Gonzalez RR CabaUem- Campo P Jasper M | 2000 | J Clin Endocrinol Metab2000，85，： | 1 |
| 8 | Scattering by FSS on anisotropic substrate for TE and TM excitation显示文摘 | Campos A L P S Melo M A B AssunClo A G | 2002 | IEEE Trans MTT2002，50，1： | 1 |
| 9 | Enhanced flux through the methylerythritol 4-phosphate pathway in Arobidopsis plants overexpressing , deoxyxylulose 5- phosphate reductoisomerase显示文摘 | CARRETERO-PAULET L CAIRO A BOTELLA-PAV:A P BE- SUMBES O CAMPOS N BORONAT A RODRfGUEZ-CONCEP- CIO M | 2006 | Plant Mol Biol2006，62，45： | 1 |
| 10 | Professional burnout and work satisfaction in Spanish allergists:Analysis of working conditions in the specialty显示文摘 | Chivato P T Campos A A Negro J M | 2011 | J Investig Allergol Clin Immunol2011，21，1： | 1 |
| 11 | Biodegradability oflingering crude oil 19 years after the Exxon Valdez oil spill显示文摘 | Venosa A D Campo P Suidan M T | 2010 | Environmental Science&Technology2010，44，19： | 1 |
| 12 | Determining corneal power using Orbscan Ⅱ videokeratography for IOL calculation after excimer laser surgery for myopia显示文摘 | Arce CG Campos M Schor P | | 0，，： | 1 |
| 13 | Implementing successful intimate partner violence screening programs in health care settings: evidence generated from a realist informed systematic review显示文摘 | O\'Campo P Kirst M Tsamis C | 2011 | Social Science Medicine2011，72，6： | 1 |
| 14 | Microstructure and wear resistance of Al-SiC composites coatings on ZE41 magnesium alloy显示文摘 | RODRIGO P CAMPO M TORRES B | 2009 | Applied Surface Science2009，255，22： | 1 |
| 15 | A unified framework for the study of anti-windup designs 显示文摘 | Kothare M V Campo P J Morari M | 1994 | Automatica1994，30，12： | 1 |
| 16 | Anatomical effects of impact noise显示文摘 | Henderson D Spongr V Subramaniam M Campo P | | 0，，： | 1 |
| 17 | Preparation of N,O-aminals as synthetic equivalents of HC=NAr and (HC=NHAr)+Ions显示文摘 | Barluenga J Bayon A M Campos P | 1988 | J Chem Soc Perkin Transl1988，7，： | 1 |
| 18 | 显示文摘 | Nair P K Nair M T S Campos J | 1987 | Proc Spie1987，823，： | 1 |
| 19 | The effect of ' condi- tioning' exposures on hearing loss from traumatic exposure 显示文摘 | Campo P Subramaniam M Henderson D | 1991 | Heating Res1991，55，2： | 1 |
| 20 | Immediate antiinflammatory effects of inhaled budesonide in patients with asthma显示文摘 | Mendes ES Rebolledo P Campos M | 2014 | Ann Am Thorac Soc2014，11，5： | 1 |
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