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| 1 | Metabolic syndrome and colorectal neoplasms:An ominous association显示文摘AIM:To evaluate the association of metabolic syndrome(MS) and colorectal cancer and adenomas in a Western country,where the incidence of MS is over 27%.METHODS:This was a prospective study between March 2013 and March 2014.MS was diagnosed according to the National Cholesterol Education ProgramATP III.Demographic characteristics,anthropometric measurements,metabolic risk factors,and colonoscopic pathologic findings were assessed in patients with MS(group 1) who underwent routine colonoscopy at our department.This data was compared with consecutive patients without metabolic syndrome(group 2),with no differences regarding sex and age.Patients with incomplete colonoscopy,family history,or past history of colorectal neoplasm were excluded.Informed consent was obtained and the ethics committee approved this study.Statistical analysis was performed using Student's t-test and χ2 test,with a P value ≤ 0.05 being considered statistically significant.RESULTS:Of 258 patients,129 had MS;51% males;mean-age 67.1 years(50-87).Among the MS group,94% had high blood pressure,91% had increased waist circumference,60% had diabetes,55% had low high-density lipoprotein cholesterol level,50% had increased triglyceride level,and 54% were obese [body mass index(BMI) 30 kg/m2].51% presented 4 criteria of MS.MS was associated with increased prevalence of adenomas(43% vs 25%,P = 0.004) and colorectal cancer(13% vs 5%,P = 0.027),compared with patients without MS.MS was also positively associated with multiple(≥ 3) adenomas(35% vs 9%,P = 0.024) and sessile adenomas(69% vs 53%,P = 0.05).No difference existed between location(P = 0.086),grade of dysplasia(P = 0.196),or size(P= 0.841) of adenomas.In addition,no difference was found between BMI(P = 0.078),smoking(P = 0.146),alcohol consumption(P = 0.231),and the presence of adenomas.CONCLUSION:MS is positively associated with adenomas and colorectal cancer.However,there is not enough information in western European countries to justify screening in patients with MS.To our knowledge,no previous study has evaluated this association in Portuguese patients. | Daniel Trabulo Suzane Ribeiro Cláudio Martins Cristina Teixeira Cláudia Cardoso Jo?o Mangualde Ricardo Freire élia Gamito Ana L Alves Fátima Augusto Ana P Oliveira Isabelle Cremers | 2015 | World Journal of Gastroenterology2015，21，17： | 5 |
| 2 | Reliable eighteenhour lung preservation at 4 degrees and 10 degrees by pulmonary artery flush after high-dose prostaglandin E1 administration显示文摘 | Mayer E Puskas J D Cardoso P F | 1992 | J Thorac Cardiovasc Surg1992，103，： | 1 |
| 3 | New tools for assessing breast cancer recurrence 显示文摘 | Dinh P Cardoso F Sotiriou C | 2008 | Cancer Treat Res2008，141，： | 1 |
| 4 | Design and planning of supply chains with integration of reverse logistics activities under demand uncertainty 显示文摘 | Cardoso S R Barbosa-Povoa A P F D Relvas S | 2013 | European Journal of Operational Re- search2013，226，： | 1 |
| 5 | Subspace methods for the blind identification of multichannel FIR filters显示文摘 | Moulines E Duhannel P Cardoso J F | 1995 | IEEE Trans on Signal Processing1995，43，2： | 1 |
| 6 | Nutritional requirement of digestible tryptophan for white-egg layers of 60 to 76 weeks of age 显示文摘 | CARDOSO A S COSTA F G P DA SILVA J H V | 2014 | The Journal of Applied Poultry Research2014，23，4： | 1 |
| 7 | A new approach to reduce membrane and transverse shear locking for one-point quadrature shell elements: linear formulation 显示文摘 | Cardoso R P R Yoon J W Valente R A F | 2006 | International Journal for Numerical Methods in Engineering2006，66，2： | 1 |
| 8 | Growth and yield of potatoes in relation to method of application of Zn fertilizers and to fungicides containing Zn显示文摘 | Moreira M A Fontes P C R Fontes R L F Cardoso A A | 2000 | Horticultura Brasileira2000，18，1： | 1 |
| 9 | Enhanced one-point quadrature shell element for nonlinear applications 显示文摘 | Cardoso R P R Yoon J W Valente R A F | 2007 | International Journal for Numerical Methods in Engineering2007，69，3： | 1 |
| 10 | Subspace methods for the blind identifieation of multichannel FIR filters显示文摘 | Moulines E Duhamel P Cardoso J F | 1995 | IEEE Transactions on Signal Proeessing1995，43，2： | 1 |
| 11 | Subspace methods for the blind indentification of multichannel FIR filters显示文摘 | MOULINES E DUHAMEL P CARDOSO J F | 1995 | IEEE Trans on Signal Processing1995，43，2： | 1 |
| 12 | Fibrous histiocytomas : histopathologic review of 95 cases 显示文摘 | Canelas M M Cardoso J C Andrade P F | 2010 | An Bras Dermatol2010，85，2： | 1 |
| 13 | Subspace Methods for the blind Identification of multichannel FIR filters显示文摘 | Duhamel P Cardoso J F | 1995 | IEEE Trans Signal Processing1995，43，2： | 1 |
| 14 | Subspace methods for the blind identification of multi-channel FIR filters显示文摘 | MOULINES E DUHAMEL P CARDOSO J F | 1995 | IEEE Trans Signal Processing1995，43，12： | 1 |
| 15 | Elemental distributionwithin single latex particles: Determination by electron spectroscopyimaging显示文摘 | Cardoso A H Leite C A P Galembeck F | 1998 | Ungmuir1998，14，12： | 1 |
| 16 | Subspace methods for the blind identification of multichannel FIR filters显示文摘 | Mouline E Duhamel P Cardoso J F | 1995 | IEEE Trans Signal Processing1995，42，2： | 1 |
| 17 | A new approach to reduce membrane and transverse shear locking for one-point quadrature shell elements: linear formulation 显示文摘 | Cardoso R P R Yoon J W Valente R A F | 2006 | International Journal for Numerical Methods in Engineering2006，66，2： | 1 |
| 18 | Depressive symptomsand perception of quality of life in Parkinson's disease显示文摘 | Scalzo P Kummer A Cardoso F | 2009 | ArqNeuropsiquiatr2009，67，2： | 1 |
| 19 | Serum levels of brain derived neurotrophic factor correlate with motor impairment in Parkinson' s disease显示文摘 | Scalzo P Kiimmer A Bretas T L Cardoso F Teixeira A L | 2010 | J Neurol2010，257，： | 1 |
| 20 | Enhanced one-point quadrature shell element for nonlinear applications 显示文摘 | Cardoso R P R Yoon J W Valente R A F | 2007 | International Journal for Numerical Methods in Engineering2007，69，3： | 1 |
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