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| 1 | Lipase-Catalyzed Synthesis of Sn-2 Palmitate: A Review显示文摘Human milk fat(HMF)is an important source of nutrients and energy for infants.Triacylglycerols(TAGs)account for about 98%of HMF and have a unique molecular structure.HMF is highly enriched in palmitic acid(PA)at the sn-2 position of the glycerol backbone(more than 70%)and in unsaturated fatty acids at the sn-1,3 position.The specific TAG structure in HMF plays a valuable function in infant growth.Sn-2 palmitate(mainly 1,3-dioleoyl-2-palmitoyl-glycerol)is one of the structured TAGs that is commonly supplemented into infant formula in order to enable it to present a similar structure to HMF.In this review,the development of the lipase-catalyzed synthesis of sn-2 palmitate over the last 25 years are summarized,with a focus on reaction schemes in a laboratory setting.Particular attention is also paid to the commercialized sn-1,3 regioselective lipases that are used in structured TAGs synthesis,to general methods of TAG analysis,and to successfully developed sn-2 palmitate products on the market.Prospects for the lipase-catalyzed synthesis of sn-2 palmitate are discussed. | Wei Wei Cong Sun Xiaosan Wang Qingzhe Jin Xuebing Xu Casimir CAkoh Xingguo Wang | 2020 | Engineering2020，6，4： | 5 |
| 2 | High Sn-2 Docosahexaenoic Acid Lipids for Brain Benefits, and Their Enzymatic Syntheses: A Review显示文摘The normal development and maintenance of central neural functions are highly correlated with the amount of docosahexaenoic acid(DHA;ω-3 fatty acid)accumulated in the brain.DHA incorporated at the sn-2 position of lipids is well absorbed by intestinal mucosa and utilized efficiently in vivo.However,modern consumers have a reduced direct intake of DHA and increased intake of saturated fats or ω-6 fatty acid oils,resulting in behavioral and neurophysiological deficits.To provide an understanding of the integrated beneficial effects of DHA on the human brain,this review introduces the positional difference(sn-2 and sn-1,3 positions)of DHA on a glycerol skeleton in natural fats and oils,and further discusses the possible functional mechanism regarding DHA supplementation and the gut-brain axis.The multiple bidirectional routes in this axis offer a novel insight into the interaction between DHA supplementation,the gut microbiota,and brain health.To achieve high sn-2 DHA in diets,it is suggested that sn-2 DHA lipids be enzymatically produced in more efficient and economical ways by improving the specific activities of lipases and optimizing the purification procedures.These types of diets will benefit individuals with strong needs for sn-2 ω-3 lipids such as infants,children,and pregnant and lactating women. | Jun Jin Qingzhe Jin Xingguo Wang Casimir CAkoh | 2020 | Engineering2020，6，4： | 5 |
| 3 | Physical properties of trans- free bakery shortening produced by lipase- catalyzed interesterification 显示文摘 | JEUNG H L CASIMIR C A KI -TEAK L | 2008 | J Am Oil Chem Soc2008，85，： | 1 |
| 4 | Four-factor response surface optimization of the enzymatic modification of triolein to structured lipids显示文摘 | Chwen-Jen Shieh Casimir C. Akoh Philip E. Koehler | 1995 | Journal of the American Oil Chemists’ Society1995，，6： | 1 |
| 5 | Ataluren (PTCI24) induces cystic fibrosis transmembrane conductance regulator pro- tein expression and activity in children with nonsense mutation cys-tic fibrosis 显示文摘 | Sermet-Gaudelus I Boeck KD Casimir GJ | 2010 | Am J Respir Crit Care Med2010，182，10： | 1 |
| 6 | Phenolic compounds and antioxidant capacity of georgia-grown blueberries and blackberries显示文摘 | SUBRAMANI S CASIMIR C A GERARD K | 2002 | Agricultural Food Chemistry2002，，50： | 1 |
| 7 | Optimized enzymatic synthesis of geranyl butyrate with lipase AY from candida rugosa 显示文摘 | SHICH C J CASIMIR C A LISA N Y | 1996 | Biotechnology and Bioengineering1996，51，2： | 1 |
| 8 | Mercury flux measurements in a naturally enriched area:correlation with environmental conditions during the Nevada Study and Test of the Release of Mercury From Soils显示文摘 | Poissant L Pilote M Casimir A 1999 | 1999 | J Geophys Res1999，104，21： | 1 |
| 9 | The value of information in the multi-item newsboy problem显示文摘 | Casimir R J | 2002 | Omega2002，30，1： | 1 |
| 10 | Neonatal serum IgE concentration as predictor of atopy显示文摘 | Duchateau J Casimir G | 1983 | Lancet1983，51，： | 1 |
| 11 | Effects of phenolic compounds in blueberries and muscadine grapes on HepG2 cell viability and apoptosis显示文摘 | Weiguang Yi Casimir C.Akoh Joan Fischer | | 0，，： | 1 |
| 12 | Strategies for a blind newsboy显示文摘 | Casimir R J | 1999 | Omega1999，27，1： | 1 |
| 13 | Enzymatic modification of triolein: Incorporation of caproic and butyric acids to produce reduced-calorie structured lipids显示文摘 | Lydia B. Fomuso Casimir C. Akoh | 1997 | Journal of the American Oil Chemists’ Society1997，，3： | 1 |
| 14 | The Use of Features Selection and Nearest Neighbors Rule for Faults Diagnostic in Induction Motors显示文摘 | BOUTLEUX E CLERC G | 2006 | Engineering Applications of Artificial Intelligence2006，，19： | 1 |
| 15 | Phenolic Compounds and Antioxidant Capacity of Georgia-Grown Blueberries and Blackberries 显示文摘 | Sellappan S Casimir C Akhon Krewer G | 2002 | Agricultural food chemistry2002，50，： | 1 |
| 16 | Mercury flux measurements in a naturally enriched area: correlation with environmental conditions during the Nevada study and tests of the release of mercury from soils (STORMS) 显示文摘 | Poissant L Pilotc M Casimir A | 1999 | Journal of Geophysical Research- Atmospheres1999，104，21： | 1 |
| 17 | Effects of phenolic compounds in bluebe-rries and muscadine grapes on HepG2 cell viability and apoptosis显示文摘 | Weiguang Yia Casimir C Akoh Joan Fischer | 2006 | Food Research International2006，39，： | 1 |
| 18 | The energy between two large uncharged conducting plates显示文摘 | Casimir H B G | 1948 | Proc K Ned Akad Wet1948，51，2： | 1 |
| 19 | Oxidation kinetics of butanol-gasoline surrogate mixtures in a jet-stirred reactor :Experimental and modeling study 显示文摘 | Philippe D Casimir T | 2008 | Fuel2008，87，1516： | 1 |
| 20 | Confucian dynamism, affective commitment, need for a- chievement, and service quality: A study on property managers in Hong Kong显示文摘 | Chan C K T Ng Y N K Casimir G | 2011 | Services Marketing Quarterly2011，32，4： | 1 |
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