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| 1 | Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review显示文摘Human papillomavirus(HPV) has been implicated in the pathogenesis of a subset of oropharyngeal squamous cell carcinoma. As a result, traditional paradigms in relation to the management of head and neck squamous cell carcinoma have been changing. Research into HPVrelated oropharyngeal squamous cell carcinoma is rapidly expanding, however many molecular pathological and clinical aspects of the role of HPV remain uncertain and are the subject of ongoing investigation. A detailed search of the literature pertaining to HPV-related oropharyngeal squamous cell carcinoma was performed and information on the topic was gathered. In this article, we present an extensive review of the current literature on the role of HPV in oropharyngeal squamous cell carcinoma, particularly in relation to epidemiology, risk factors, carcinogenesis, biomarkers and clinicalimplications. HPV has been established as a causative agent in oropharyngeal squamous cell carcinoma and biologically active HPV can act as a prognosticator with better overall survival than HPV-negative tumours. A distinct group of younger patients with limited tobacco and alcohol exposure have emerged as characteristic of this HPV-related subset of squamous cell carcinoma of the head and neck. However, the exact molecular mechanisms of carcinogenesis are not completely understood and further studies are needed to assist development of optimal prevention and treatment modalities. | Robbie SR Woods Esther M O'Regan Susan Kennedy Cara Martin John J O'Leary Conrad Timon | 2014 | World Journal of Clinical Cases2014，2，6： | 5 |
| 2 | Potential of phytoremediation for treatments of PAHs in soil at MGP sites显示文摘 | Pradhan S P Conrad J R Paterek J R | 1998 | J Soil Contam1998，7，： | 2 |
| 3 | Mean-reversion in short-horizon individual security return显示文摘 | Conrad J Kaul G | 1989 | Journal of Financial Economics1989，29，： | 1 |
| 4 | Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma eell lines显示文摘 | Mader J S Salsman J Conrad D M | 2005 | Mol Cancer Ther2005，4，4： | 1 |
| 5 | Spatial Survey of Trace Metal Contaminants in the Sediments of the Elizabeth River,Virginia显示文摘 | Conrad F Chisholm-Brause C J | 2004 | Marine Pollution Bulletin2004，49，： | 1 |
| 6 | 显示文摘 | Wong A Luth H J Decether Conrad W | 2001 | Brain Res2001，920，12： | 1 |
| 7 | Separate pathways for cellular uptake of ferric and fer- rous iron显示文摘 | CONRAD M E UMBREIT J N MOORE E G | 2000 | American Journal of Physiology : Gastro- intestinal and Liver Physiology2000，279，： | 1 |
| 8 | Purification of Spider Silk-elastin from Transgenic Plants and Application for Human Chondrocyte Proliferation显示文摘 | Jürgen Scheller Daniele Henggeler Angelika Viviani Udo Conrad | 2004 | Transgenic Research2004，，1： | 1 |
| 9 | Polymorphisms in K13 and falcipain-2 associated with artemisinin resistance are not prevalent in Plasmodium falciparum isolated from Ugandan children 显示文摘 | Conrad MD Bigira V Kapisi J | 2014 | PLoS One2014，9，10： | 1 |
| 10 | E-PTFE(Gore-Tex) suspension cervical facial rhytidectomy显示文摘 | Conrad K Chapnik J S Reifen E | 1993 | Arch Otolaryngol Head Neck Surg1993，119，6： | 1 |
| 11 | Components of short-horizon individual security returns显示文摘 | Conrad J Kaul G Nimalendran M | 1991 | Journal of Financial Economics1991，29，： | 1 |
| 12 | Hyponatremia in intraeranial disorders 显示文摘 | Conrad M J Meinders Aortal J C | 2001 | Net J Med2001，58，3： | 1 |
| 13 | Flavones from Scutellaria baicalensis Georgi attenuate apoptosis and protein oxidation in neuronal cell lines显示文摘 | Choi J Conrad C C Malakowsky C A | 2002 | Biochim Biophys Acta2002，1571，： | 1 |
| 14 | Neospora-like encephalomyelitis in a calf: pathology, ultrastrueture, and immuno-reactivity显示文摘 | BARR B C CONRAD P A DUBEY J P | 1991 | J Vet Dia gn Invest1991，3，1： | 1 |
| 15 | Stereochemistry of cyclic compounds显示文摘 | Bruns K Conrad J Steigel A | 1979 | Tetrahedron1979，35，： | 1 |
| 16 | Advanced glycation end products co-localize with inducible nitric oxide synthase in Alzheimer's disease 显示文摘 | Wong A Luth H J Deut her Conrad W | 2001 | Brain Res2001，920，12： | 1 |
| 17 | Effect of bevacizumabon radiation necrosis of the brain 显示文摘 | Gonzalez J Kumar A J Conrad CA | 2007 | lnt J Radiat Oncol Biol Phys2007，67，2： | 1 |
| 18 | Critical national infrastructure reliability modeling and analysis 显示文摘 | Conrad S H LeClaire R J O' Reilly G P | 2006 | Bell Labs Technical Journal2006，11，3： | 1 |
| 19 | Transcranial Doppler ultrasonography of carotid-basilar collateral circulation in subclavian steal显示文摘 | Klingelh6fer J Conrad B Benecke R | 1988 | Stroke1988，19，8： | 1 |
| 20 | Colony (Grain) Size Reduction in Eutectic Pb-Sn Castings by Electroplusing 显示文摘 | Sprecher A F Conrad H | 1995 | Scripta Metallurgica et Materialia1995，32，6： | 1 |
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