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| 1 | 水解蛋白质化学改性(英文)显示文摘从含铬废弃物提取的水解蛋白质与不同量的戊二醛 ,在不同的温度下反应。用聚酰胺凝胶电泳法 (SDS -PAGE)分析了改性蛋白质的分子量及分子量分布。用CanonManning粘度法测定了改性产物的粘度。实验表明改性产物的分子量随戊二醛的用量增加而增加。最佳的戊二醛用量约为水解胶原质量的 12 % ,反应温度大于 6 0℃。同时 ,用改性产物做了皮革的填充实验 ,用萤光标记改性胶原 ,通过扫描电镜研究了填充皮革的纤维结构。研究结果表明 ,改性产物具有较好的填充性能 ,采用适当的应用工艺 ,改性产物可能用作皮革填充剂。 | 陈武勇 Brown E M Taylor M M Cooke P H Marmer W N | 2002 | 四川大学学报(工程科学版)2002，34，6： | 9 |
| 2 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 3 | Factor analysis identifies subgroups of constipation显示文摘AIM:To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction.METHODS:One hundred and ninety-one patients presenting to a Gastroenterology clinic with constipation and 32 constipated patients responding to a newspaper advertisement completed a 53-item,wide-ranging selfreport questionnaire.One hundred of these patients had colonic transit measured scintigraphically.Factor analysis determined whether constipation-related symptoms grouped into distinct aspects of symptomatology.Cluster analysis was used to determine whether indi-vidual patients naturally group into distinct subtypes.RESULTS:Cluster analysis yielded a 4 cluster solution with the presence or absence of pain and laxative unresponsiveness providing the main descriptors.Amongst all clusters there was a considerable proportion of patients with demonstrable delayed colon transit,irritable bowel syndrome positive criteria and regular stool frequency.The majority of patients with these characteristics also reported regular laxative use.CONCLUSION:Factor analysis identified four constipation subgroups,based on severity and laxative unresponsiveness,in a constipated population.However,clear stratification into clinically identifiable groups remains imprecise. | Philip G Dinning Mike Jones Linda Hunt Sergio E Fuentealba Jamshid Kalanter Denis W King David Z Lubowski Nicholas J Talley Ian J Cook | 2011 | World Journal of Gastroenterology2011，17，11： | 3 |
| 4 | 显示文摘 | Cooke D W Bennett B L Farnum E H | 1997 | Appl Phys Lett1997，70，： | 2 |
| 5 | 高羊茅干草部分替代玉米和紫花苜蓿青贮饲料对奶牛消化、泌乳性能的影响显示文摘试验旨在研究高羊茅干草替代玉米或紫花苜蓿青贮对奶牛中性洗涤纤维(NDF)消化率、泌乳性能的影响。选取初产哺乳荷斯坦奶牛(产奶75±35 d)24头,经产荷斯坦奶牛(产奶68±19 d)40头,随机分成4组,共设置32个进料闸门,记录采食量。每组8个进料阀门,以1头牛为1个试验单位,每头牛试验过程中可接触8个进料闸门。试验用高羊茅干草(TF)取代玉米青贮饲料(CS)或紫花苜蓿青贮饲料(AS),试验设计为:33%AS和67%CS(空白组)、60%TF和40%AS(试验1组)、60%TF和40%CS(试验2组)、33%TF和67%CS(试验3组)。试验进行7周,前2周进行预饲。试验结果表明,各组间牛奶产量无显著差异,平均值为40.4 kg·d^(-1)。各组间牛奶中脂肪含量和浓度、蛋白质含量和浓度均无显著差异,平均值为1.58 kg·d^(-1)和3.94%、1.28 kg·d^(-1)和3.15%。与试验1组(22.1 kg·d^(-1))、试验3组(22.7 kg·d^(-1))相比,空白组的干物质摄入量最高,为24.5kg·d^(-1)。各组间总的干物质消化率无显著差异,平均值为66.2%。与试验2组(44.4%)、试验3组(45.3%)相比,空白组的NDF消化率较低,为37.8%,与试验1组(42.4%)相近。各组间奶牛体内NDF消化率(42.3%)与预估的NDF消化率(42.6%)相近。试验结果表明,饲喂高羊茅干草可提高饲料中NDF消化率,部分替代玉米和紫花苜蓿时对产奶量无显著影响,在市场价格较低时,可作为经济实用的奶牛饲料。 | Bender R W Lopes F Cook D E Combs D K | 2016 | 饲料博览2016，0，8： | 2 |
| 6 | Rock mechanics ap - plied to the study of mckbursts 显示文摘 | Cook N G W Hook E Pretorious J P G | 1966 | J S Afr Inst Min Metall1966，66，10： | 1 |
| 7 | The biologically active isomers of conjugated linoleic acid显示文摘 | PARIZA M W PARK Y COOK M E | 2001 | Progress in Lipid Research2001，40，： | 1 |
| 8 | The deuterium to hydrogen ratios of sap in trees: implications for water sources and tree ring deuterium to hydrogen ratios显示文摘 | White J W C Cook E R Lawrence J R | 1985 | Geochimica Et Cosmochimiea Aeta1985，49，： | 1 |
| 9 | Trans-10, cis-12 octa- decadienoic acid increases lymphocyte proliferation 显示文摘 | DeVoney D Pariza M W Cook M E | 1999 | FASEB1999，，： | 1 |
| 10 | Toxic equivalency factors of polychlorinated dibenzo-p-dioxin, dibenzofuran and biphenyl congeners based on early life stage mortality in rainbow trout ( Oncorhynchus mykiss) 显示文摘 | Zabel E W Cook P M Peterson R E | 1995 | Aquatic Toxicology1995，31，： | 1 |
| 11 | The Effect of time Delay and Growth Rate Inhibition in the Bacterial Treatment of Wastewater显示文摘 | Bush A W Cook S E | 1975 | J Thoo- ret Biol1975，63，： | 1 |
| 12 | Rock mechanics applied to the study of rockbursts显示文摘 | Cook N G W,Hoek E,Pretorius J P G, | 1966 | Journal of the South African Institute of Mining and1966，66，10： | 1 |
| 13 | The prolactin gene is located on chromosome 6 in humans显示文摘 | OWERBACH D RUTTER W J COOKE N E | 1981 | Science1981，212，4496： | 1 |
| 14 | Endoscopic partial inferior turbinoplasty显示文摘 | DELDEN M R COOK P R DAVIS W E | 1999 | Otolaryngol Head Neck Surg1999，121，： | 1 |
| 15 | Compilation of Energy Band Gap in Elemental and Binary Compound Semiconductors and Insulators 显示文摘 | Streldow W H Cook E L | 1973 | Phys Chem Ref Data1973，2，1： | 1 |
| 16 | Second-Generation RISC Floating Point with Multiply-Add Fused显示文摘 | E Hokenek R K Montoye P W Cook | 1990 | IEEE Journal of Solid-State Circuits1990，25，5： | 1 |
| 17 | Thermally stimulated luminescence from x-irradiated porous silicon显示文摘 | Cooke D W Bennett B L Farnum E H | 1997 | Appl Phys Lett1997，70，26： | 1 |
| 18 | A synthetic oestrus- exciting compound显示文摘 | Cook J W Dodds E C Hewtt C L | 1933 | Nature1933，131，： | 1 |
| 19 | Compilation of energy band gap in elemental and binary compound semiconductors and insulators显示文摘 | Strehlow W H Cook E L | 1973 | Phys Chem Ref Data1973，2，1： | 1 |
| 20 | Transition stages of ray- leigh-Taylor instability between miscible fluids显示文摘 | Cook A W Dimotakis P E | 2001 | Journal of Fluid Mechanics2001，443，： | 1 |
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