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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial显示文摘 | Faramarz Ismail-Beigi Timothy Craven Mary Ann Banerji Jan Basile Jorge Calles Robert M Cohen Robert Cuddihy William C Cushman Saul Genuth Richard H Grimm Bruce P Hamilton Byron Hoogwerf Diane Karl Lois Katz Armand Krikorian Patrick O'Connor Rodica Pop-Bus | 2010 | The Lancet2010，，9739： | 2 |
| 3 | Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus显示文摘 | Call K M Glaser T Ito C Y | 1990 | Ce111990，60，3： | 1 |
| 4 | Isolation and characterization of zine finger polypeptide gene at the human chromosome 11 wilms' tumor locus 显示文摘 | Call K M Glaser T Ito C Y | 1990 | Cell1990，，60： | 1 |
| 5 | Physicians' knowledge of inhaler devices and inha- lation techniques remains poor in Spain显示文摘 | Plaza V Sanchis J Roma P Molina J Calle M Quirce S Viejo JL Ca- ballero F Murio C | 2012 | J Aerosol Med Pulm Dm8 Deliv2012，25，1： | 1 |
| 6 | Inflammation and type 2 diabetes显示文摘 | Calle M C Fernandez M L | 2012 | Di- abetes Metab2012，38，3： | 1 |
| 7 | Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms tumor loeus显示文摘 | Call K M Glaser T Ito C Y | 1990 | Ce111990，60，3： | 1 |
| 8 | E~valuation of the R2R11M11O7 pyrochlores as cathodes in solid-oxide fuel cells 显示文摘 | CORONADO R M AGUADERO A CALLE C | 2011 | J Power Sources2011，196，： | 1 |
| 9 | Discrete element modeling(DEM) of triboelectricaUy charged particles: revised experiments显示文摘 | HOGUE M D CALLE C I CURRY D R | 2009 | Journal of Electrostatics2009，67，4： | 1 |
| 10 | 显示文摘 | Calle M Garcia C Lozano A E | 2013 | Journal of Membrane Science2013，434，： | 1 |
| 11 | Reversible cerebral seg- mental vasoconstriction显示文摘 | Call G K Fleming M C Sealfon S | 1988 | Stroke1988，19，9： | 1 |
| 12 | Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial显示文摘 | Faramarz Ismail-Beigi Timothy Craven Mary Ann Banerji Jan Basile Jorge Calles Robert M Cohen Robert Cuddihy William C Cushman Saul Genuth Richard H Grimm Bruce P Hamilton Byron Hoogwerf Diane Karl Lois Katz Armand Krikorian Patrick O’Connor Rodica Pop-Bus | 2010 | 2010 (9739)2010，，9739： | 1 |
| 13 | 显示文摘 | CALLE M B BRUNORI C SCERBO R | 1997 | J Anal At Spectrom1997，12，： | 1 |
| 14 | Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms’ tumor locus显示文摘 | Call K M Glaser T Ito C Y | 1990 | Cell1990，60，3： | 1 |
| 15 | Ce-ZSM-5 catalysts for the selective catalytic reduction of NOx in stationary diesel exhaust gas显示文摘 | Van KOOTEN W E J LIANG B KRIJNSEN H C OUDSHOORN O L CALLS H P A Van den BLEEK C M | 1999 | Appl Catal B1999，21，3： | 1 |
| 16 | Lung cancer,cardiopulmonary mortality and long_term exposure to fine particulate air pollution显示文摘 | Pope C A Burnett R T Thun M J Calle E E Krewski D Ito K Thurston G D | | 0，，： | 1 |
| 17 | Parvovirus H-1 infection of human glioma cells leads to complete viral replication and efficient cell killing显示文摘 | Herrero Y Calle M Cornelis JJ Herold-Mende C | 2004 | Int J Cancer2004，109，1： | 1 |
| 18 | Investigation of the hypothalamo- pituitmy-adrenal axis (HPA) by 1 mierog ACTH test and metyrapone test in patients with primary fibromyalgia syndrome 显示文摘 | Calls M C-6kee C Ates F | 2004 | J Endocrinol Invest2004，27，1： | 1 |
| 19 | Ofatumumab-based chemoimmunotherapy is effective and well tolerated in patients with previously untreated chronic lymphocytic leukemia(CLL)显示文摘 | SHANAFELT T LANASA M C CALL T G | 2013 | Cancer2013，119，： | 1 |
| 20 | Local chain mobility dependence on molecular structure in polyimides with bulky side groups: Correlation with gas separation properties 显示文摘 | Calle M Garcia C Lozano A E | 2013 | Journal of Membrane Science2013，434，： | 1 |
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