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| 1 | Postpartum depression:A systematic review of the genetics involved显示文摘Postpartum depression is one of the most prevalent psychopathologies. Its prevalence is estimated to be between 10% and 15%. Despite its multifactorial etiology, it is known that genetics play an important role in the genesis of this disorder. This paper reviews epidemiological evidence supporting the role of genetics in postpartum depression(PPD). The main objectives of this review are to determine which genes and polymorphisms are associated with PPD and discuss how this association may occur. In addition, this paper explores whether these genes are somehow related to or even the same as those linked to Major Depression(MD). To identify gaps in the current knowledge that require investigation, a systematic review was conducted in the electronic databases Pub Med, LILACS and Sci ELO using the index terms 'postpartum depression' and 'genetics'. Literature searches for articles in peerreviewed journals were made until April 2014. PPD was indexed 56 times with genetics. The inclusion criteria were articles in Portuguese, Spanish or English that were available by institutional means or sent by authors upon request; this search resulted in 20 papers. Genes and polymorphisms traditionally related to MD, which are those involved in the serotonin, catecholamine, brain-derived neurotrophic factor and tryptophan metabolism, have been the most studied, and some have been related to PPD. The results are conflicting and some depend on epigenetics, which makes the data incipient. Further studies are required to determine the genes that are involved in PPD and establish the nature of the relationship between these genes and PPD. | Tiago Castro e Couto Mayra Yara Martins Brancaglion António Alvim-Soares Lafaiete Moreira Frederico Duarte Garcia Rodrigo Nicolato Humberto Corrêa Regina Amélia Lopes P Aguiar Henrique Vitor Leite | 2015 | World Journal of Psychiatry2015，5，1： | 5 |
| 2 | 非甾体抗炎药应用中,环氧合酶2、不对称二甲基精氨酸与心血管危害的关系显示文摘已有大规模、安慰剂对照试验确定了非甾体类抗炎药(nonsteroidal anti—inflammatory drugs,NSAIDs)具有心血管危害性:这归因于环氧合酶2(cyclooxygenase,COX-2)的心脏保护产物受到抑制,尤其是前列环素(prostacyclin,PG12)。NSAID降低心脏保护作用的另一种机制可能是通过增强肾脏中甲基精氨酸的形成来限制一氧化氮在整个脉管系统中的作用。 | Ricciotti E Castro C Tang SY Briggs WTE West JA Malik D Rhoades SD Meng H Li X Lahens NF Sparks JA Karlson EW Weljie AM Griffin JL FitzGerald GA6 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，9： | 3 |
| 3 | Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans显示文摘 | Bamberger CM Bamberger AM de Castro M | 1995 | J Clin Invest1995，95，： | 1 |
| 4 | Glucocorticoid receptor β,a potential endogenous inhibitor of glucocorticoid action in humans显示文摘 | Bamberger CM Bamberger AM de Castro M | 1995 | J Clin Invest1995，95，6： | 1 |
| 5 | Laparoscopic and classic cholecystectomy in patients with liver cirrhosis显示文摘 | Poniachik J Castro S Madrid AM | 2002 | Rev Med Chil2002，130，12： | 1 |
| 6 | Aztreonam/clavulanic acid in the treatment of serious infections caused by Stenotrophomonas maltophilia in neutropenic patients:case reports显示文摘 | 8,Garcia Sanchez JE Vazquez Lopez ML Blazquez de Castro AM | 1997 | J Chemother1997，9，3： | 1 |
| 7 | Effect of percutaneous transluminal coronary angioplasty on circulating endothelin levels显示文摘 | Kaul S Castro L | 1993 | Am J Cardiol1993，72，： | 1 |
| 8 | Renal in-jury study in critical ill patients in accordance withthe new definition given by the Acute Kidney InjuryNetwork 显示文摘 | Fonseca-Ruiz NJ Castro DP Guerra AM | 2011 | J Crit Care2011，26，2： | 1 |
| 9 | A benign retroperitoneal schwannoma: a review of the literature and a report of a new case显示文摘 | Cortes AI Ferngmdez AM Castro BF | 1999 | Actas Urol Esp1999，23，7： | 1 |
| 10 | Efficacy of sublingual specific immunotherapy on allergic asthma and rhinitis in children's real life 显示文摘 | De Castro G Zicari AM Indinnimeo L | 2013 | Eur Rev Med Pharmacol Sci2013，17，16： | 1 |
| 11 | Sin- gleoincision sling compared with transobturator sling for treating stress urinary incontinence: a randomized controlled trial 显示文摘 | Bianehi-Ferraro AM Jarmy-Di Bella ZI Castro Rde A | 2013 | Int Urogynecol J2013，24，9： | 1 |
| 12 | Cytochrome P450 reductase-mediated anaerobic biotransformation of ethanol to 1-hydroxyethylfree radicals and acetaldehyde 显示文摘 | Diaz Gomez MI Castro GD de Layno AM Costantini MH Castro JA | 2000 | Toxicology2000，154，13： | 1 |
| 13 | Identification of a bioactive compound isolated from Brazilian propolis type 6 显示文摘 | Castro ML do Nascimento AM Ikegaki M | 2009 | Bioorg MedChem2009，17，14： | 1 |
| 14 | Randomized controlled trial comparing TVT-O and TVT-S for the treatment of stress urinary incontinence: 2-year results显示文摘 | Bianchi-Ferraro AM Janny-DiBella ZI de Aquino Castro R et al | 2014 | Int Urogynecol J2014，25，10： | 1 |
| 15 | Glucagonoma synd- rome: a case report 显示文摘 | Castro PG de Leon AM Trancon JG | 2011 | J Med Case Rep2011，5，： | 1 |
| 16 | Importance of ethical and psychological features in the intersex management 显示文摘 | Spinola - Castro AM | 2005 | Arq Bras Endocrinol Metab2005，49，1： | 1 |
| 17 | Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate显示文摘 | Castro J Harrington AM Hughes PA | 2013 | Gastroenterology2013，145，6： | 1 |
| 18 | Glucocorticold receptor beta, a potential endogenous inhibitor of glncocorticoid action in humans显示文摘 | Bamberger CM Bamberger AM de Castro M | 1995 | J Clin Invest1995，95，： | 1 |
| 19 | Random izad study of bipolar vessel sealing system versysconventional suture ligature for vaginal hysterectomy显示文摘 | Silva-Filho AL Rodrigues AM Vale de Castro M on teino M | 2009 | Eur JObstet Gynecol Reprod Biol2009，146，2： | 1 |
| 20 | Coevolution of T-cell receptors with MHC and non-MHC ligands显示文摘 | Castro CD Luoma AM Adams EJ | 2015 | Immunol Rev2015，267，： | 1 |
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