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| 1 | Hepatitis C virus:A global view显示文摘Hepatitis C virus(HCV) is a global challenge; 130-175 million are chronically infected. Over 350000 die each year from HCV. Chronic HCV is the primary cause of cirrhosis, hepatocellular carcinoma(HCC), and end-stage liver disease. Management of chronic HCV is aimed at preventing cirrhosis, reducing the risk of HCC, and treating extra hepatic complications. New treatments for chronic HCV has been devoted based on direct-acting antivirals, as pegylated interferon(peginterferon) is responsible for many side effects and limits treatment access. Sofosbuvir is the first compound to enter the market with Peginterferon-free combination regimens. | Amal Ahmed Mohamed Tamer A Elbedewy Magdy El-Serafy Naglaa El-Toukhy Wesam Ahmed Zaniab Ali El Din | 2015 | World Journal of Hepatology2015，7，26： | 7 |
| 2 | HepG2 cells support viral replication and gene expression of hepatitis C virus genotype 4 in vitro显示文摘瞄准:与丙肝的长期的复制建立一个房间文化系统病毒(HCV ) 染色体和病毒的抗原的表示在试管内。方法:HepG2 房间线被孵化与长期的丙肝从一个病人与浆液为它的危险性测试到 HCV。房间和上层清液在文化期间在各种各样的时间点被收获。文化上层清液为它感染天真的房间的能力被测试。存在减(反感觉) 在房间的核心和 E1 抗原的 RNA 海滨,和察觉被 RT-PCR 和免疫学的技术(流动血细胞计数和西方的污点) 分别地检验。结果:细胞内部的 HCV RNA 首先在 d 上被检测 3 在感染以后然后能一致地在至少三个月的一个时期上在房间和上层清液被检测。新鲜房间能从有教养的感染的房间感染上层清液。流动 cytometric 分析证明表面和在房子里使用的细胞内部的 HCV 抗原表示使 polyclonal 成为了抗体(反核心,和 anti-E1 ) 。西方的污点分析证明在分子量的产生免疫性的肽的簇的表示在一个月内在 31 和 45 kDa 之间延长了感染的房间的旧文化而这簇在 uninfected HepG2 房间是无法发现的。结论:HepG2 房间线产生 HCV 感染而且支持它的复制在试管内不仅。HCV 结构的蛋白质的表示能在感染的 HepG2 房间被检测。这些房间也能够流病毒的粒子进接着对 uninfected 房间变得传染的培养基。 | Mostafa K El-Awady Ashraf A Tabll Yasmine S El-Abd Mahmoud M Bahgat Hussein A Shoeb Samar S Youssef Noha G Bader El Din El-Rashdy M Redwan Maha El-Demellawy Moataza H Omran Wael T El-Garf Said A Goueli | 2006 | World Journal of Gastroenterology2006，12，30： | 2 |
| 3 | Modifica- tions in energy demand in urban areas as aresult of climate changes: an assessment for thesoutheast Mediterranean region显示文摘 | CARTALIS C SYN DIN u A PROEDROU M | 2001 | Energy Conversion&Management2001，42，14： | 1 |
| 4 | Aspirin inhibitsmTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells 显示文摘 | Din FV Valanciute A Houde VP | 2012 | Gas troenterology2012，142，7： | 1 |
| 5 | Investigation of Oil Swelling Packers 显示文摘 | A1 Yami A S Nasr - E1 - Din H A | 2008 | SPE 1131352008，，： | 1 |
| 6 | An Electrochemical and Esca Study on the Tarnishing of Silver in Solutions of Different pS and pH Values显示文摘 | DIN A M Shams El KADER J M Abd El WAHAB F M Abd El | 1985 | Electrochimica Acta1985，30，4： | 1 |
| 7 | Adsorption of methylene blue onto bamboo-based activated carbon: kinetics and equilibrium studies 显示文摘 | Hameed B H Din A T M Ahmad A L | 2007 | J Hazard Mate2007，141，3： | 1 |
| 8 | Investigation of a high temperature organic water shut- off gel: reaction mechanisms显示文摘 | AL-MUNTASHERI G A NASR EL DIN H A PETERS J | 2006 | SPE Journal2006，11，49： | 1 |
| 9 | Inactivations,deletions,non-adjudications,and downgrades of clinical endpoints on ticagrelor:serious concerns over the reliability of the PLATO trial显示文摘 | DiN icolantonio JJ Tomek A | 2013 | Int J Cardiol2013，168，4： | 1 |
| 10 | Stress intensity factors for fatigue cracking of round bars 显示文摘 | Din A S S E Lovegrove J M | 1981 | International Journal of Fatigue1981，3，3： | 1 |
| 11 | Target Strength for Fish Identification Using Echo Sounder显示文摘 | SUNARDI DIN J YUDHANA A | | 0，，02： | 1 |
| 12 | Rapid testing versus karyotyping in Down' s syndrome screening: cost-effectiveness and detection of clinically significant chromosome abnormalities显示文摘 | Gekas J van den Berg DG Din'and A | 2011 | Eur J Hum Genet2011，19，1： | 1 |
| 13 | Ameliomoration of the physiologic and biochemical changes of acute pancreatitis using an antiTHF-α polyclonal antibody显示文摘 | Grewal HP Moheyel Din A Graber L | 1994 | Am J Surg1994，167，1： | 1 |
| 14 | Investigation of Water - Swelling Packers 显示文摘 | A1 Yami A S Nasr E1 Din H A | 2008 | SPE 1148142008，，： | 1 |
| 15 | Wheat gluten: high molecular weight glutenin subunits-structure, genetics, and relation to dough elasticity 显示文摘 | Anjum F M Khan M R Din A | 2007 | Journal of Food Science2007，72，3： | 1 |
| 16 | New HPLC-chemometric approaches to the analysis of isoflavones in Trifolium lucanicum Gasp显示文摘 | Kükboyaci N Güven A Din E | | 0，，17： | 1 |
| 17 | Adsorption of methylene blue onto bamboo - based activated car- bon:Kinetics and equilibrium studies 显示文摘 | Hameed B H Din A T M Ahmad A L | 2007 | J Hazard Mater2007，141，： | 1 |
| 18 | Serum nerve growth factor levels in autistic children in Turkish population:apreliminary study显示文摘 | Dinel N nalp A Kutlu A | 2013 | Indian J Med Res2013，138，6： | 1 |
| 19 | Protective efficacy of recombinant modified vaccinia virus ankara delivering middle east respiratory syndrome coronavirus spike glycoprotein显示文摘 | Volz A Kupke A Song F Jany S Fux R Shams-El- din H Schmidt J Becker C Eickmann M Becker S Sutter G | 2015 | J Virol2015，89，16： | 1 |
| 20 | Paediatric and adult colonic manometry: A tool to help unravel the pathophysiology of constipation显示文摘Colonic motility subserves large bowel functions, including absorption, storage, propulsion and defaecation. Co-lonic motor dysfunction remains the leading hypothesis to explain symptom generation in chronic constipation, a heterogeneous condition which is extremely prevalent in the general population, and has huge socioeconomic impact and individual suffering. Physiological testing plays a crucial role in patient management, as it is now accepted that symptom-based assessment, although im-portant, is unsatisfactory as the sole means of directing therapy. Colonic manometry provides a direct method for studying motor activities of the large bowel, and this review provides a contemporary understanding of how this technique has enhanced our knowledge of normalcolonic motor physiology, as well as helping to elucidate pathophysiological mechanisms underlying constipation. Methodological approaches, including available catheter types, placement technique and recording protocols, are covered, along with a detailed description of re-corded colonic motor activities. This review also criti-cally examines the role of colonic manometry in current clinical practice, and how manometric assessment may aid diagnosis, classification and guide therapeutic inter-vention in the constipated individual. Most importantly, this review considers both adult and paediatric patients. Limitations of the procedure and a look to the future are also addressed. | Philip G Dinning Marc A Benninga Bridget R Southwell S Mark Scott | 2010 | World Journal of Gastroenterology2010，16，41： | 1 |
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