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| 1 | Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume显示文摘Objective:To investigate the hypolipidaemic and antioxidant effects of aqueous leaf extract of Enicoslemma littorale(E.littorale)Blume(Ens)against ethanol induced hepatic injury in albino rats.Methods:Male albino rats of six numbers in each group were undertaken for study.Hypolipidaemic and antioxidant effect of E.littorale Blume(Ens)aqueous leaf extract at a dosage of 250 mg/kg bw was evaluated.Results:Levels of serum and tissue cholesterol,triglycerides and free fatty acids were elevated and levels of tissue thiobarbituric acid reactive substances(TBARS)and lipid hydroperoxide were increased in ethanol treated rats.The activity levels of liver antioxidant enzymes such as superoxide dismutase(SOD),catalase(CAT),glutathione peroxidase(GPX)and glutathione-s-transferase(GST)were decreased.After adiminstration of extract of E,littorale Blume,levels of cholesterol,triglycerides and free fatty acids were decreased in serum and liver tissue,levels of TBARS and lipid hydroperoxide were decreased,and Ever antioxidant enzymes were increased in liver tissue;Conclusions:It can be concluded that the aqueous leaf extract of E,littorale Blume(Ens)has potent restorative effect on hyperlipidaemic and oxidative stress. | Thirumalai T Viviyan Therasa S Elumalai EK David E | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，5： | 12 |
| 2 | Hypoglycemic effect of Brassica juncea(seeds) on streptozotocin induced diabetic male albino rat显示文摘Objective:To evaluate the hypoglycemic effect of Brassica juncea(seeds) on streptozotocin induced diabetic male albino rats.Methods:Hypoglycemic activity of Brassica juncea(seeds)aqueous extract at a dose of 250,350 and 450 mg/kg body weight was evaluated.Adult male Swiss albino rats of six numbers in each group was undertaken for study and evaluated.Results:The serum insulin levels were recorded a significant depletion in all groups,short term as well as long term diabetic animals,when compared to that of normal animals.A significant dosage dependent augmenting effect of the seed extract on the serum insulin was recorded in both short term as well as long term groups.Conclusions:The aqueous seed extract of Brassica juncea has potent hypoglycemic activity in male albino rat. | T Thirumalai S Viviyan Therasa EK Elumalai E David | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 9 |
| 3 | Antibacterial activity of various leaf extracts of Merremia emarginata显示文摘Objective:To investigate the antibacterial activity and phytochemical screening of the aqueous.methanol and petroleum ether leaf extracts of Merremia emarginata(M.emarginata).Methods:The antibavterial activity of leaf extracts of M.emarginata were evaluated by agar well diffusion method against four selected bacterial species.Results:The presence of tannins,flavonoids,amino acids,starch,glycosides and carbohydrates in the different leaf extracts was established.The methanol extract was more effective against Baciilus cereus and Eseherkhia coli,whereas aqueous extract was more effective against Staphylococcus aureus and Pseudomonas aeruginosa.Condusions:The results in the present study suggest that M.emarginata leaf can be used in treating diseases caused by the tested organisms. | EK Elumalai M Ramachandran T Thirumalai P Vinothkumar | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，5： | 8 |
| 4 | Molecular studies resolve Nyholmiella (Orthotrichaceae) as a separate genus显示文摘Two Orthotrichum species of the subgenus Orthophyllum were compared with other representatives of this genus using internally transcribed spacer regions 1 and 2,the chloroplast trnH-psbA region,and inter-simple sequence repeat(ISSR)and intron-exon splice conjunction(ISJ)markers.The ISSR and ISJ markers used revealed many bands and mutations specific only to O.gymnostomum and O.obtusifolium.Phylogenetic analysis clearly supported previous concepts postulating that species of the subgenus Orthophyllum should be recognized as the separate genus Nyholmiella. | Jakub SAWICKI Vítězslav PLEK Monika SZCZECINSKA | 2010 | Journal of Systematics and Evolution2010，48，3： | 4 |
| 5 | Single balloon enteroscopy for endoscopic retrograde cholangiography in patients with Roux-en-Y hepaticojejuno anastomosis显示文摘AIM:To evaluate single balloon enteroscopy in diagnostic and therapeutic endoscopic retrograde cholangiography(ERC)in patients with Roux-en-Y hepaticojejunoanastomosis(HJA).METHODS:The study took place from January 2009to December 2011 and we retrospectively assessed 15patients with Roux-en-Y HJA who had signs of biliary obstruction.In total,23 ERC procedures were performed in these patients and a single balloon videoen-teroscope(Olympus SIF Q 180)was used in all of the cases.A transparent overtube was drawn over the videoenteroscope and it freely moved on the working part of the enteroscope.Its distal end was equipped with a silicone balloon that was inflated by air from an external pump at a pressure of≤5.4 kPa.The technical limitations or rather the parameters of the single balloon enteroscope(working length-200 cm,diameter of the working channel-2.8 mm,absence of Albarran bridge)showed the need for special endoscopic instrumentation.RESULTS:Cannulation success was reached in diagnostic ERC in 12 of 15 patients.ERC findings were normal in 1 of 12 patients.ERC in the remaining 11 patients showed some pathological changes.One of these(cystic bile duct dilation)was subsequently resolved surgically.Endoscopic treatment was initialized in the remaining 10 patients(5 with HJA stenosis,2 with choledocholithiasis,and 3 with both).This treatment was successful in 9 of 10 patients.The endoscopic therapeutic procedures included:balloon dilatation of HJA stenosis-11 times(7 patients);choledocholitiasis extraction-five times(5 patients);biliary plastic stent placement-six times(4 patients);and removal of biliary stents placed by us-six times(4 patients).The mean time of performing a single ERC was 72 min.The longest procedure took 110 min and the shortest took34 min.This shows that it is necessary to allow for more time in individual procedures.Furthermore,these procedures require the presence of an anesthesiologist.We did not observe any complications in these 15 patients.CONCLUSION:This method is more demanding than standard endoscopic retrograde cholangiopancreatography due to altered postsurgical anatomy.However,it is effective,safe,and widens the possibilities of resolving biliary pathology. | Bohuslav Kianika Jan Lata Ivo Novotny Petr Dítě Jirí Vaníek | 2013 | World Journal of Gastroenterology2013，19，44： | 2 |
| 6 | 顽固性高血压与由心内容积决定的血管内液体潴留无关显示文摘顽固性高血压(refractory hypertension,RfHTN)是一种极端的抗高血压治疗失败的表现形式,定义为使用了包括长效噻嗪类和盐皮质激素受体拮抗剂在内的≥5种药时血压仍控制欠佳。RfHTN是难治性高血压(resistant hypertension,RHTN)的一个亚组,RHTN定义为使用≥3种降压药(包括利尿剂)后血压仍〉135/85mm Hg(1mm Hg=0.133kPa)。 | 刘青 叶鹏 Velasco A Siddiqui M Kreps E Kolakalapudi P Dudenbostel T Arora G Judd EK Prabhu SD Lloyd SG Oparil S Calhoun DA | 2018 | 中华高血压杂志2018，26，7： | 2 |
| 7 | Intense and exhaustive exercise induce oxidative stress in skeletal muscle显示文摘 | T Thirumalai S Viviyan Therasa EK Elumalai E David | 2011 | Asian Pacific Journal of Tropical Disease2011，，1： | 2 |
| 8 | High performance InP/InGaAs heterostructure bipolar transistors grown by metalorganic vapor phase epitaxy显示文摘 | Nottenburg R N Chen Y K Tanbun- Ek T | 1989 | Appl Phys Lett1989，55，： | 2 |
| 9 | Electrical stimulation of the gasserian ganglion induces structural alterations of calcitionin gene-related peptide immunoreactive perivascular sensory nere terminals in the rat cerebral duramater a possible model of migraine headache显示文摘 | Janos T ajti Mohtashan S | 1995 | Neurosclence letters1995，，： | 1 |
| 10 | Regulation of E-and P-cadherin expression correlated with melanocyte migration and diversification显示文摘 | Nishimura EK Yoshida H Kunisada T | 1999 | Dev Biol1999，215，2： | 1 |
| 11 | Multi-objective simulation-based evolutionary algorithm for an aircraft spare parts allocation problem显示文摘 | Loo H L Ek P C Suyan T | 2008 | European Journal of Operational Research2008，189，： | 1 |
| 12 | Activation of vagal afferents after intravenous injection of interleukin-lB: Role of endogenous prostaglandins显示文摘 | Ek M Kurosawa M Lundeberg T | 1998 | Neurosci1998，18，22： | 1 |
| 13 | Radiographic left ventricular- right ventricular intcrlead distance predicts the acute hemodynamic response to cardiac resynchronization therapy 显示文摘 | Heist EK Fan D Mela T | 2005 | Am J Cardiol2005，96，5： | 1 |
| 14 | Multi-objective simulation-based evolutionary algorithm for an aircraft spare parts allocation problem 显示文摘 | Loo H L Ek P C Suyan T | | European Journal of Operational Research0，200，189： | 1 |
| 15 | Cardiovascular risk prediction in the general population with use of suPAR, CRP, and Framingham Risk Score 显示文摘 | Lyngb~ek S Marott J L Sehestedt T | 2013 | International journal of cardiology2013，167，6： | 1 |
| 16 | Expression of drug metabolizing enzymes in hepatocyte-like ceils derived from human embryonic stem cells显示文摘 | Ek M Soderdahl T Kuppers-Munther B | 2007 | Biochem Pharmaeol2007，74，3： | 1 |
| 17 | Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision显示文摘 | Bro ek J L Bousquet J Baena-Cagnani C E Bonini S Canonica G W Casale T B | 2010 | J Allergy Clin Immunol2010，126，： | 1 |
| 18 | Maintenance therapy with Thalidomide improves overall survival after autologous hematopoietic progenitor cell transplantation for multiple myeloma 显示文摘 | Brinker BT Waller EK Leong T | 2006 | Cancer2006，106，10： | 1 |
| 19 | VIS absorption spectrophotometry of disperse dyes 显示文摘 | GOLOB V EK L T | 1999 | Dyes and Pigments1999，，40： | 1 |
| 20 | QIIME allows analysis of high-throughput community sequencing data 显示文摘 | Caporaso JG Kuczynski J Stombaugh J Bittinger K Bushman FD Costello EK Fierer N Pena AG Goodrich JK Gordon JI Huttley GA Kelley ST Knights D Koenig JE Ley RE Lozupone CA Mcdonald D Muegge BD Pirrung M Reeder J Sevinsky JR Tumbaugh PJ Walters WA Widmann J Yatsunenko T Zaneveld J Knight R | 2010 | Nat Methods2010，7，5： | 1 |
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