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| 1 | Screening and analysis of the multiple absorbed bioactive components and metabolites of Dangguibuxue decoction by the metabolic fingerprinting technique and liquid chromatography/diode-array detection mass spectrometry显示文摘 | Wang, P Liang, YZ Zhou, N Chen, BM Yi, LZ Yu, Y Yi, ZB | 2007 | 中国生物学文摘2007，21，11： | 31 |
| 2 | Identification of tumor associated single-chain Fv by panning and screening antibody phage library using tumor cells显示文摘AIM:To study the feasibility of panning and screeningphage-displaying recombinant single-chain variablefragment (ScFv) of anti-tumor monoclonal antibodiesfor fixed whole cells as the carriers of mAb-bindingantigens.ME,ODS: The recombinant phage displaying librariesfor anti-colorectal tumor mAb MC3Ab, MC5Ab andanti-gastric tumor mAb MGD1 was constructed.Panning and screening were carried outby means ofmodified fixation of colorectal and gastric tumor cellsexpressed the mAb-binding antigens. Concordance ofbinding specificity to tumor cells between phageclones and parent antibodies was analyzed. Thephage of positive clones was identified withcompetitive ELISA, and infected by E.coli HB2151 toexpress soluble ScFv.RESULTS:The ratio of positive clones to MC3-ScF-MC5-ScFv and MGD1-ScFv were 60 %, 24 % and 30 %. MC3-ScFv had Mr 32 000 confirmed by Western blot. Thespecificity to antigen had no difference between 4positive recombinant phage antibodies and MC3Ab.CONCLUSION:The modified process of fixing wholetumor cells is efficient, convenient and feasible to panand screen the phage-displaying ScFv of anti-tumormonoclonal antibodies. | Nie, YZ He, FT Li, ZK Wu, KC Cao, YX Chen, BJ Fan, DM | 2002 | World Journal of Gastroenterology2002，8，4： | 12 |
| 3 | Purging of murine erythroblastic leukemia by ZnPcS2P2-based-photodynamic therapy显示文摘 | Huang HF Chen YZ Wu Y Chen P | 2006 | 中国生物学文摘2006，20，5： | 5 |
| 4 | NEW ALDALOIDS TONGOLINE AND TONGOLININE FROMDELPHINIUM TONGOLENSE显示文摘NEWALDALOIDSTONGOLINEANDTONGOLININEFROMDELPHINIUMTONGOLENSELanHE;YaoZuCHEN(TheChemistryDepartmentofLanzhouUniversity,Lanzhou7... | He, L Chen, YZ Ding, LS Li, BG | 1996 | Chinese Chemical Letters1996，7，6： | 4 |
| 5 | Rapid activation of JNK and p38 by glucocorticoids in primary cultured hippocampal cells显示文摘 | Qi AQ Qiu J Xiao L Chen YZ | 2005 | 第二军医大学学报2005，26，10： | 3 |
| 6 | TWO NORDITERPENOID ALKALOIDS FROM ACONITUM LEUCOSTOMUM显示文摘TWO NORDITERPENOID ALKALOIDS FROM ACONITUM LEUCOSTOMUMTWONORDITERPENOIDALKALOIDSFROMACONITUMLEUCOSTOMUM￥JianMinYUE;JunXUandHa... | Yue, JM Xu, J Sun, HD Chen, SN Chen, YZ | 1996 | Chinese Chemical Letters1996，7，8： | 2 |
| 7 | 6-O-Benzoylgomisin O,a new lignan from the fruits of Schizandra chinensis 显示文摘 | Chen CC Shen CC Shih YZ | 1994 | J NatProd1994，57，8： | 1 |
| 8 | Synthesis and characterization of a novel cationic chitosan-based ?occulant with a high water-solubility for pulp mill wastewater treatment 显示文摘 | Wang JP Chen YZ Yuan SJ | 2009 | Water Research2009，，43： | 1 |
| 9 | Nitrite accumulation by aeration controlled in sequencing batch reac- tors treating domestic wastewater显示文摘 | Peng YZ Chen Y Peng CY | 2004 | Water Science and Technology2004，50，10： | 1 |
| 10 | Suppression of mitogenesis and regulation of cell cycle traverse by resveratrol in cultured smooth muscle cells 显示文摘 | Zou JG Huang YZ Chen Q | 1999 | Int J Oncol1999，15，： | 1 |
| 11 | Simultaneous quantification of loureirin A and loureirin B in rat urine,feces,and bile by HPLC-MS/MS method and its application to excretion study显示文摘 | Zhang YS Li YZ Chen B | 2011 | Analytical and Bioanalytical Chemistry2011，400，： | 1 |
| 12 | The p73 gene is less involved in the development but involved in the progression of neuroblastoma 显示文摘 | Piao HY Chen YZ | 2000 | Int J Mol Med2000，5，4： | 1 |
| 13 | Sorption of perfluorooctane sulfonate (PFOS) on oil and oil-derived black carbon, influence of solution pH and 显示文摘 | Chen H Chen S Quan X Zhao YZ Zhao HM | 2009 | Chemosphere2009，77，10： | 1 |
| 14 | Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction显示文摘 | Zhou S Chen HZ Wan YZ | 2011 | Circ Res2011，109，： | 1 |
| 15 | Protective effect of Uli- nastatin against murine models of sepsis: inhibition of TNF-α and IL-6 and augmentation of IL-10 and IL-13 显示文摘 | Cao YZ Tu YY Chen X | 2012 | Exp Toxieol Pathol2012，64，6： | 1 |
| 16 | Relationship between Serum Bilirubin and Carotid Atherosclerosis in Hypertensive Patients显示文摘 | Yang XF Chen YZ Su JL | | 0，，： | 1 |
| 17 | Sonic hedgehog enhances the proliferation and osteogenie differentiation of bone marrow-derived mesenchymal stem cells显示文摘 | Cai JQ Huang YZ Chen XH | 2012 | Cell Biol Int2012，36，4： | 1 |
| 18 | Frequencies of epitope- specific cytotoxic T lymphocytes in active chronic viral hepatitis B infection by using MHC class I peptide tetramers 显示文摘 | Wu YZ Zhang J Chen SY | 2004 | Immunol Lett2004，92，3： | 1 |
| 19 | Long-term effects of aniotensin Ⅱ type 2(AT2) receptor null mutation on renal fibronectin deposition and PA/PAI regulation显示文摘 | Li W Chen XM Ye YZ | 1998 | J American Soc Nephrol1998，9，： | 1 |
| 20 | Laparoscopic cholecystectomy foracute cholecystitis:a quantitative operation indications显示文摘 | Hu GZ Chen ZB Guo YZ | 2009 | J lapa-roscopic surgery2009，8，1： | 1 |
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