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| 1 | Mobius Isoparametric Hypersurfaces in S^(n+1) with Two Distinct Principal Curvatures | Hai Zhong LI Department of Mathematics, Tsinghua University. Beijing 100084. P. R. China Hui Li LIU Department of Mathematics, Northeastern University. Shenyang 110000. P. R. China Chang Ping WANG Key Laboratory of Pure and Applied Mathematics, School of Mathematical Sciences. Peking University, Beijing 100871, P. R. China Guo Song ZHAO Department of Mathematics, Sichuan University, Chengdu 610064. P. R. China | 2002 | Acta Mathematica Sinica,English Series2002，18，3： | 53 |
| 2 | Impacts of permafrost changes on alpine ecosystem in Qinghai-Tibet Plateau显示文摘Alpine cold ecosystem with permafrost environment is quite sensitive to climatic changes and the changes in permafrost can significantly affect the alpine ecosystem. The vegetation coverage, grassland biomass and soil nutrient and texture are selected to indicate the regime of alpine cold ecosystems in the Qinghai-Tibet Plateau. The interactions between alpine ecosystem and permafrost were investigated with the depth of active layer, permafrost thickness and mean annual ground temperature (MAGTs). Based on the statistics model of GPTR for MAGTs and annual air temperatures, an analysis method was developed to analyze the impacts of permafrost changes on the alpine ecosystems. Under the climate change and human engineering activities, the permafrost change and its impacts on alpine ecosystems in the permafrost region between the Kunlun Mountains and the Tanggula Range of Qinghai-Tibet Plateau are studied in this paper. The results showed that the per- mafrost changes have a different influence on different alpine ecosystems. With the increase in the thickness of active layer, the vegetation cover and biomass of the alpine cold meadow exhibit a significant conic reduction, the soil organic matter content of the alpine cold meadow ecosystem shows an exponential decrease, and the surface soil materials become coarse and gravelly. The alpine cold steppe ecosystem, however, seems to have a relatively weak relation to the permafrost environment. Those relationships resulted in the fact that the distribution area of alpine cold meadow decreased by 7.98% and alpine cold swamp decreased by 28.11% under the permafrost environment degradation during recent 15 years. In the future 50 years the alpine cold meadow ecosystems in different geomorphologic units may have different responses to the changes of the permafrost under different climate warming conditions, among them the alpine cold meadow and swamp ecosystem located in the low mountain and plateau area will have a relatively serious degradation. Furthermore, from the angles of grassland coverage and biological production the variation characteristics of high-cold eco- systems in different representative regions and different geomorphologic units under different climatic conditions were quantitatively assessed. In the future, adopting effective measures to protect permafrost is of vital importance to maintaining the stability of permafrost engineering and alpine cold eco- systems in the plateau. | WANG Genxu1,3 , LI Yuanshou2 , WU Qingbai2 & WANG Yibo3 1. Institute of Mountain Hazards and Environment, Chinese Academy of Sciences, Chengdu 610041, China 2. Cold and Arid Regions Environmental and Engineering Research Institute, Chinese Academy of Sciences, Lanzhou 730000, China 3. Resource and Environment School, Lanzhou University, Lanzhou 730000, China | 2006 | Science China Earth Sciences2006，49，11： | 41 |
| 3 | Pancreatic microcirculatory impairment in experimental acute pancreatitis in rats显示文摘AIM: To study the feature of pancreatic microcirculatoryimpairment, especially the initial changes, in caerulein-induced experimental acute pancreatitis (AP).METHODS: The pancreatic microcirculation of caerulein-induced AP model was studied by intravital fluorescencemicroscopy with FITC-labeled erythrocytes (FITC-RBC),scanning electron microscopy of vascular corrosion casts,and light microscopy of Chinese ink-injected/cleared tissues.RESULTS: Animals in caerulein-treated group showedhyperamylemia (× 2), pancreatic oedema, infiltration ofinflammatory cells in pancreas. Constrictions of intralobulararteriolar sphincters, presence of vacuoles in all layers ofsphincter, and gross irregularity in capillary network of aciniwere found in the AP specimens. The decrease of pancreaticcapillary blood flow (0.34±0.10 nl @ min-1 vs0.910.06 nl @rain-1 of control, P<0.001), reduction of functional capillarydensity(277± 13 cm-1 vs349±8 cm-1 of control, P<0.001),and irregular intermittent perfusion were observed incaerulein-induced groups.CONCLUSION: Impairment and constriction of pancreaticintralobular arteriolar sphincter are the initial microcirculatorylesions in the early phase of acute pancreatitis, and play akey role in the pancreatic ischaemia and pancreaticmicrovascular failure in acute pancreatitis. | Zong-Guang Zhou You-Dai Chen Wei Sun Zhong Chen,Ⅲ Department of General Surgery(Gastroenteric Surgery),West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China | 2002 | World Journal of Gastroenterology2002，8，5： | 49 |
| 4 | Effects of the tyrosine protein kinase inhibitor genistein on the proliferation,activation of cultured rat hepatic stellate cells显示文摘AIM: Hepatic stellate cell (HSC) plays a pivotal role inliver fibrosis and is considered as the therapeutic targetfor the treatment of hepatic fibrosis. Tyrosine proteinkinase plays an important role in the proliferation,activation of HSC. The purpose of the study is toinvestigate the effects of the tyrosine protein kinaseinhibitor genistein onthe proliferation and activationof cultured rat HscMETHODS: Rat HSC were isolated from Wistar rats by insitu perfusion of collagenase and pronase and single-stepdensity Nycodenz gradient. Culture-activated HSC wereserum-starved and incubated with 10-3 to 10-5 mol/Lconcentration of genistein for 24, 48 or 72 h. In PDGF-induced HSC proliferation, HSC were stimulatel with L0μg@L-1PDGF-BB for 15 min, and then treaeed with genisteinfor the same time. Cell proliferation was measured byMTr assay and based on flow cytometric analysis of cellcycle. The a-smooth muscle actin (α-SMA) expression inHSC was studied with confocal laser microscopy and flowcytometry. c-fos c-jun and cyclin D1 expression in HSCwas also detected by flow cytometry.RESULTS: Genistein inhibited basal and PDGF-inducedproliferation of HSC at the concentration of 10-8 to 10-5mol/L, and treatment with 10-7 mol/L concentration ofgenistein for 48 h inhibited the HSC proliferationsignificantly (the inhibition rate was 70.3 %, P<0.05).Immunofluorescence detected by confocal lasermicroscopy and flow cytometry showed that treatmentwith 10-7 mol/L genistein for 48 h suppressed theexpression of α-SMA significantly in HSC (the specificfluorescence intensity were 60.2±21.5 vs 35.3±11.6and 12.8± 10.4 vs9.54±6.39, respectively, both P<0.05).The intensity of c-fos, c-jun and cydin D1 expression ofHSCs treated with 10-7 mol/L genistein for 48 h wasalso significantly decreased compared with the controls.CONCLUSION: Genistein influences proliferation of HSC,suppresses the expression of α-SMA in HSC and tinhibits the intensity of c-fos, c-jun and cyclin D1expression of HSCs. Genistein has therapeutic potentialagainst liver fibrosis. | Xiao-Jing Liu Ming-Hui Huang Laboratory of Department of Internal Medicine,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China Li Yang Qiong Wang Yi-Ping Wang Department of Gastroenterology of West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China Yong-Qiu Mao Center for Cancer Biotherapy of West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China Hong-Bin Wu Laboratory of Department of Surgery,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China | 2002 | World Journal of Gastroenterology2002，8，4： | 38 |
| 5 | Assessment of candidate plant DNA barcodes using the Rutaceae family显示文摘DNA barcoding is a rapidly developing frontier technology that is gaining worldwide attention.Here,seven regions (psbA-trnH,matK,ycf5,rpoC1,rbcL,ITS2,and ITS) with potential for use as DNA barcodes were tested for their ability to identify 300 samples of 192 species from 72 genera of the family Rutaceae.To evaluate each barcode’s utility for species authentication,PCR amplification efficiency,genetic divergence,and barcoding gaps were assessed.We found that the ITS2 region exhibited the highest inter-specific divergence,and that this was significantly higher than the intra-specific variation in the 'DNA barcoding gap' assessment and Wilcoxon two-sample tests.The ITS2 locus had the highest identification efficiency among all tested regions.In a previous study,we found that ITS2 was able to discriminate a wide range of plant taxa,and here we confirmed that ITS2 was also able to discriminate a number of closely related species.Therefore,we propose that ITS2 is a promising candidate barcode for plant species identification. | LUO Kun1,2,CHEN ShiLin1,CHEN KeLi2,SONG JingYuan1,YAO Hui1,MA XinYe1,ZHU YingJie3,PANG XiaoHui1,YU Hua1,LI XiWen1,4 & LIU Zhen2 1Institute of Medicinal Plant Development,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100193,China 2College of Pharmacy,Hubei University of Chinese Medicine,Wuhan 430061,China 3School of Bioscience and Engineering,Southwest Jiaotong University,Chengdu 610031,China 4Department of Chemistry,Tsinghua University,Beijing 100084,China | 2010 | Science China(Life Sciences)2010，53，6： | 32 |
| 6 | 论信息系统集成的实施显示文摘本文以笔者从事信息系统集成的经验为基础,讨论了信息系统集成的内涵、实施信息系统集成的三种模式及其利弊、适用场合。 | Zeng Huashen College of Computer & Comun Engi ,Southwest Jiaotong Univ.,Sichuan·Chengdu 610031 | 1997 | 计算机应用1997，17，2： | 32 |
| 7 | HLA class Ⅰ expression in primary hepatocellular carcinoma显示文摘AIM:To investigate whetherCTL vaccine therapy is suitable for primary hepatocellular carcinoma(HCC)from the viewpoint of HLA classIantigens expression.METHODS:The immunocytochemistry,image analysis,flow cytometry,and labeled streptavidin bioti(LSAB)method of immunohistochemistry were applied respectively to study 4HCCcell lines(e.g.Alexander,HepG2,SMMC-7721,andQGY-7703)cultured in vitro and 6frozen tissue specimens of HCC.RESULTS:The positive control cell line Raji had very strong positive staining,Most mitotic and nonmitotic cells of the 4HCCcell lines had various intensity of HLAclassⅠantigens expression.The negative control cell K562 and the control slides of all the cell lines had no positive staining,In the 6HCCspecimens immunohistochemically studied,histological normal hepatocytes had no or very weak positive staining and the liver sinus had very strong positive staining.Most HCCcells in the sections from the 6HCCspecimens had strong positive HLAclassⅠantigens staining.The positive staining was located in the cytoplasm,the perinuclear area,and at the cell membrane of the liver cancer cells.Flow cytometry also revealed that Raji and those 4HCCcell lines had strong HLAclassⅠantigens expression.which was confirmed quantitatively by the image analysis.It showed that the objective grayscale values of Raji and those 4HCCcell lines were significantly different from that of K562(Raji114.04±10.94,Alexander165.97±5.35,HepG2167.02±12.60,QGY-7703161.46±7.13,SMMC-7721 165.93±5.21,K562244.89±4.60,P<0.01).Significant differences were also found ebtween Raji and the 4HCCcell lines.CONCLUSION:HCC cells express HLA classI antigens strongly,Fromthis point of view.the active specific immunotherapy of CTL vaccine is suitable and practicable for HCC. | Jian Huang Mei-Ying Cai Da-Peng Wei Immunology Department,West China University of Medical Sciences,Chengdu 610044,Sichuan Province,China | 2002 | World Journal of Gastroenterology2002，8，4： | 33 |
| 8 | Laparoscopic total mesorectal excision of low rectal cancer with preservation of anal sphincter:A report of 82 cases显示文摘AIM: To assess the feasibility and efficacy of laparoscopic total mesorectal excision (LTME) of low rectal cancer with preservation of anal sphincter.METHODS: From June 2001 to June 2003, 82 patients with low rectal cancer underwent laparoscopic total mesorectal excision with preservation of anal sphincter. The lowest edge of tumors was below peritoneal reflection and 1.5-7 cm from the dentate line (1.5-5 cm in 48 cases, 5-7 cm in 34 cases).RESULTS: LTME with anal sphincter preservation was performed on 82 randomized patients with low rectal cancer, and 100 % sphincter preservation rate was achieved. There were 30 patients with laparoscopic low anterior resection (LLAR) at the level of the anastomosis below peritoneal reflection and 2 cm above from the dentate line; 27 patients with laparoscopic ultralow anterior resection (LULAR) at the level of anastomoses 2 cm below from the dentate line; and 25 patients with laparoscopic coloanal anastomoses (LC AA) at the level of the anastomoses at or below the dentate line. No defunctioning ileostomy was created in any case. The mean operating time was 120 minutes (ranged from 110-220 min), and the mean operative blood loss was 20 mL (ranged from 5-120 mL).Bowel function was restored and diet was resumed on day 1 or 2 after operation. The mean hospital stay was 8 days (ranged from 5-14). Postoperative analgesics were used in 45 patients. After surgery, 2 patients had urinary retention, one had anastomotic leakage, and another 2patients had local recurrence one year later. No interoperative complication was observed.CONCLUSION: LTME with preservation of anal sphincter is a feasible, safe and minimally invasive technique with less postoperative pain and rapid recovery, and importantly, it has preserved the function of the sphincter. | Zong-Guang Zhou Zhao Wang Yong-Yang Yu Ye Shu Zhong Cheng Li Li Wen-Zhang Lei Tian-Cai Wang Department of General Surgery and Institute of Digestive Surgery,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China | 2003 | World Journal of Gastroenterology2003，9，7： | 33 |
| 9 | Draining Tangjiashan Barrier Lake after Wenchuan Earthquake and the flood propagation after the dam break显示文摘Tangjiashan Barrier Lake is one of the largest barrier lakes caused by the Wenchuan Earthquake. Its risk analysis, emergency plan and effect of the emergency plan are introduced in this paper. The dam height of Tangjiashan Barrier Dam is about 105 m, and the reservoir storage capacity is 3.2×108 m3. When the dam broke the flood peak were estimated to be larger than 48000 m3/s, which might cause a enormous disaster to the downstream cities and residents. A discharge channel with 13 m deep and 8 m wide was drug, so that the water may flow out of the lake before the dam breaks. As a result, the drainage and risk mitigation project are successful. During the drainage process, the flood peak was about 6500 m3/s, and about 1.6×108 m3 of water was drained off and the residual reservoir capacity was only 8.97×107 m3. A new channel with average width 100 m was formed, which can bear floods of 200 years frequency. The successful experience and the collected data can be used to deal with the similar natural disasters in future. | LIU Ning1, ZHANG JianXin2, LIN Wei3, CHENG WuYI4 & CHEN ZuYu5 1 Ministry of Water Resources of the People’s Republic of China, Beijing 100053, China 2 Bureau of Hydrology of the Ministry of Water Resources of the People’s Republic of China, Beijing 100053, China 3 Sichuan Hydrographic and Water Resources Survey Bureau Chengdu 610031, China 4 HydroChina Chengdu Engineering Corporation, Chengdu 610072, China 5 China Institute of Water Resources and Hydropower Research, Beijing 100044, China | 2009 | Science China(Technological Sciences)2009，52，4： | 29 |
| 10 | Energy analysis for damage and catastrophic failure of rocks显示文摘The development history and current state of studies on the characteristics and mechanisms of deformation and failure of rock materials were briefly reviewed from the viewpoint of energy.The main scope and the achievable objectives of the energy-based research system were expatiated.It was validated by experiments that the damage process of rocks can be well described by the rock damage evolution equation established based on energy dissipation.It was found from the uniaxial compression and biaxial compression tests that only a small proportion of the total input energy in hard rocks is dissipated before peak load and a large proportion in soft rocks is dissipated before peak load.For both hard and soft rocks,the energy dissipated after peak load accounts for a greater proportion.More energy would be required for rock failure under equal biaxial compression than under unequal biaxial compression.The total absorbed energy is different for rock failure under high-rate loading and low-rate loading.More fragmented failure pattern usually corresponds to higher energy absorption.The mesoscopic analysis on the damage and failure of bedded salt rocks showed that the energy dissipation is prominent and the total absorbed energy for rock failure is low when cracks propagate in the weak mud interlayer while it is contrary when cracks propagate in the salt rock.The energy accumulation,transfer,dissipation and release during the failure process of tunnel with impending failure under disturbance were analyzed theoretically based on the elastoplastic mechanics theory.Furthermore,the spatial distribution of energy dissipation and energy release of fractured rocks under unloading was simulated numerically.It was demonstrated that energy is likely to be released from the weakest surface under compression,which triggers the global failure of rocks. | XIE HePing 1,2,LI LiYun 2,1,JU Yang 2,PENG RuiDong 2 & YANG YongMing 2 1 Sichuan University,Chengdu 610065,China 2 State Key Laboratory of Coal Resources and Safe Mining,Beijing Key Laboratory of Fracture and Damage Mechanics of Rock and Concrete,China University of Mining and Technology,Beijing 100083,China | 2011 | Science China(Technological Sciences)2011，54，S1： | 29 |
| 11 | Polymorphism of p16INK4a gene and rare mutation of p15INK4b gene exon2 in primary hepatocarcinoma显示文摘INTRODUCTION Hepatocellular carcinoma(HCC)is the mostcommon cause of death from cancer in China.Themechanisms of hepatocarcinogenesis are not yetknown clearly,p16INK4a gene,the multiple tumorsuppressor gene 1(MTS1),encodes P16 protein,which acts as an inhibitor by binding directly toCDK4 and CDK6 and preventing its association | Yang Qin Bo Li Yong Shu Tan Zhi Lin Sun Feng Qiong Zuo Ze Fang Sun Institute of Biochemistry and Molecular Biology,West China University of Medical Sciences,Chengdu 610041,Sichuan Province,China Department of General Surgery,The First Affiliated Hospital,West China University of Medical Sciences,Chengdu 610041,Sichuan Province,China Department of Pathology,The First Affiliated Hospital,West China University of Medical Sciences,Chengdu 610041,Sichuan Province,China | 2000 | World Journal of Gastroenterology2000，6，3： | 30 |
| 12 | Different Effects of Homocysteine and Oxidized Low Density Lipoprotein on Methylation Status in the Promoter Region of the Estrogen Receptor α Gene显示文摘我们调查了人的效果半胱氨酸(Hcy ) 和在雌激素受体高山的倡导者区域的 DNA methylation 上的氧化低密度脂蛋白(ox-LDL ) 哈(ERalpha ) 基因,和它在动脉粥样硬化的致病的潜在的机制。人的有教养的光滑的肌肉房间(SMC ) 被 Hcy 和 ox-LDL 为时间的不同经期与不同集中对待。DNA methylation 地位是由嵌套的 methylation 特定的聚合酶链反应的 assayed,在 SMC 和泡沫房间形成积累了的类脂化合物被检验,油红 O 染色。SMC 的增长是由 the3-(4,5-dimethylthiazol-2-yl ) 的 assayed -2,5-diphenyltetrazolium 溴化物方法。结果证明 ox-LDLin 节制导致的集中(10-40 mg/L ) 在 SMCs.However 的 ERagene 的倡导者区域的 de novo methylation, ox-LDL 的高集中(50 mg/L ) ,导致了时代的 demethylation。 Hcytreatment 与 aconcentration 在时代基因的倡导者区域导致了 de novo methylation --并且对待时间依赖者举止,并且在 SMCproliferation.These 数据上支持效果的一个剂量依赖者显示为动脉粥样硬化的二个风险因素有在 SMCs.However 的时代基因的倡导者区域导致 de novo methylation 的功能, ox-LDL 的高集中( 50 mg/L )导致了 demethylation ,显示有不同力量力量的动脉粥样硬化的不同风险因素在时代基因的倡导者区域引起不同异常 methylation 模式。Hcy 的 atherogenic 机制可能包含 hypermethylationof 时代基因,在动脉粥样硬化患者损害导致 SMC 的增长。 | Yushan HUANG~1 Kejun PENG~2 Juan SU~1 Yuping HUANG~3 Yizhon XU~1 and Shuren WANG~1 ~1Department of Pathophysiology,West China School of Preclinic Medical Sciences & Forensic Medicine,Sichuan University,Chengdu 610041.China ~2Department of Laboratory Medicine,Chengdu Medical College,Chengdu 610500,China ~3Department of Biochemistry and Molecular Bilogy,Gannan Medical College,Ganzhou 341000,China | 2007 | Acta Biochimica et Biophysica Sinica2007，39，1： | 25 |
| 13 | Some open problems in granular matter mechanics显示文摘Granular matter is a large assemblage of solid particles, which is fundamentally different from any other type of matters, such as solid and liquid. Most models presented for granular matter are phenomenological and are only suitable for solving engineering problems. Many fundamental mechanical problems remain open. By analyzing characteristics of internal state structure, we propose that granular matter is intrinsically multiscale, i.e. microscale of particle size, mesoscale of force chain, and macroscale of the bulk of granular matter. The correlations among difference scales would be crucial. The mesoscale force chain network is determined by both particle properties and macroscopic boundary conditions. The evolution of the force the chain network contributes to macroscopic mechanical properties of granular matter. In addition, we discuss the drawbacks in simplifying contact forces in the current models, and the difficulties in analyzing the interaction of interstitial fluid in wet granular matter. As an appropriate application of granular matter, debris flow can be studied with granular matter mechanics; meanwhile, debris flow brings more challenges which certainly motivate future studies on granular matter. | Qicheng Sun a, Guangqian Wanga, Kaiheng Hub a Department of Hydraulic Engineering, State Key Laboratory for Hydroscience and Engineering, Tsinghua University, Beijing 100084, China b Institute of Mountain Hazards and Environment, Chinese Academy of Sciences, Chengdu 610041, China | 2009 | Progress in Natural Science:Materials International2009，19，5： | 25 |
| 14 | Numerical simulation of air-water two-phase flow over stepped spillways显示文摘Stepped spillways for significant energy dissipation along the chute have gained interest and popularity among researchers and dam engineers. Due to the com- plexity of air-water two-phase flow over stepped spillways, the finite volume computational fluid dynamics module of the FLUENT software was used to simulate the main characteristics of the flow. Adopting the RNG k-ε turbulence model, the mixture flow model for air-water two-phase flow was used to simulate the flow field over stepped spillway with the PISO arithmetic technique. The numerical result successfully reproduced the complex flow over a stepped spillway of an experiment case, including the interaction between entrained air bubbles and cavity recirculation in the skimming flow regime, velocity distribution and the pressure profiles on the step surface as well. The result is helpful for under-standing the detailed information about energy dissipation over stepped spillways. | CHENG Xiangju1, CHEN Yongcan1 & LUO Lin2 1. Department of Hydraulic Engineering, Tsinghua University, Beijing 100084, China 2. State Key Laboratory of Hydraulics and Mountain River Engineering, Sichuan University, Chengdu 610065, China | 2006 | Science China(Technological Sciences)2006，49，6： | 23 |
| 15 | Average slip rate, earthquake rupturing segmentation and recurrence behavior on the Litang fault zone, western Sichuan Province, China显示文摘The Litang fault zone (LFZ) is an active fault zone within the northwestern Sichuan sub-block. Field investigation reveals new evidence for its late Quaternary offset, neoteric earthquake ruptures and surface-rupturing segmentation, from which long-term slip-rates, char-acteristic earthquake magnitudes and recurrence intervals on the fault zone are estimated. This study shows that the LFZ consists of three subordinate faults, and they are the northern Maoyaba fault, Litang fault and Kangga-Dewu fault, respectively. All of them are dominated by left-lateral strike-slip with reverse dip-slip component on different segments. Based on offset landforms and ages of relevant deposits collected from seven sites, it is estimated that the average left-lateral slip-rate on the LFZ reaches 4.0±1.0 mm/a in the past 14 ka BP, and vertical (reverse) dip-slip rate in the range of 0.1―1.8 mm/a. Three subordinate faults are independent earthquake rup-turing segments, on which the maximum moment magnitude of the characteristic earthquakes is estimated to be 7.0―7.3, and their average recurrence interval to be 500―1000 a. The latest earthquake ruptures occurred 119±2 years ago on the northern Maoyaba fault, about 1890 AD on the Litang fault, and in 1948 AD on the Kangga-Dewu fault, and this may indicate a unidirectional migration for surface rupturing earthquakes along the Litang fault zone, related to stress trigger-ing between the segments. | XU Xiwei1, WEN Xueze2, YU Guihua1, ZHENG Rongzhang1, LUO Haiyuan2 & ZHENG Bin2 1. Institute of Geology, China Earthquake Administration, Beijing 100029, China 2. Earthquake Administration of Sichuan Province, Chengdu 610041, China | 2005 | Science China Earth Sciences2005，48，8： | 23 |
| 16 | A new scoring system for assessment of liver function after successful hepatectomy in patients with hepatocellular carcinoma显示文摘BACKGROUND:Whether a major liver resection is safe has been judged mainly from the patient's hepatic reserve.However,a safe limit for liver resection does not exist yet.This study aimed to construct a new scoring system as a guide to determine a safe limit for liver resection and avoid liver dysfunction after hepatectomy.METHODS:Eighty-six patients with hepatocellular carcinoma who had undergone hepatectomy in West China Hospital from March 2007 to June 2010 were reviewed.The patients were classified according to the levels of total bilirubin after hepatectomy and the parameters in the perioperative period were compared.Receiver operating characteristic (ROC) analysis was made to assess the liver function compensatory (LFC) value to predict liver dysfunction of the patients after hepatectomy.LFC value is defined as the preoperative KICG value×22.487+standard remnant liver volume (SRLV)×0.020.RESULTS:Patients were classified into group Ⅰ (normal group,n=69) and group Ⅱ (with total bilirubin >85.5 μmol/L for 7 days after hepatectomy,n=17) based on the levels of total bilirubin after hepatectomy.Group II was further divided into two subgroups:recovered subgroup (n=14) and fatal subgroup (n=3).There were no significant differences in preoperative data or intraoperative findings except the indocyanine green test parameters (KICG and ICG R15) and SRLV.ROC analysis showed that the sensitivity and specificity of an LFC value ≤13.01 were 94.1% and 82.6% respectively for predicting liver dysfunction of the patients after hepatectomy.CONCLUSIONS:The LFC value appears to be a good predictor of postoperative liver dysfunction in patients who undergo hepatectomy for HCC.An expected LFC value of 13.01 seems to be a safe limit for liver resection. | Zheng-Gui Du,Bo Li,Yong-Gang Wei,Jie Yin,Xi Feng and Xi Chen Department of Liver and Vascular Surgery,West China Hospital,Sichuan University,Chengdu 610041,China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 23 |
| 17 | Investigation of changes in properties of water under the action of a magnetic field显示文摘The properties of water and their changes under the action of a magnetic field were gathered by the spectrum techniques of infrared, Raman, visible, ultraviolet and X-ray lights, which may give an insight into molecular and atomic structures of water. It was found that some properties of water were changed, and a lot of new and strange phenomena were discovered after magnetization. Magnetized water really has magnetism, which has been verified by a peak shift of X-ray diffraction of magnetized water + Fe3O4 hybrid relative to that of pure water + Fe3O4 hybrid, that is a saturation and memory effect. The properties of infrared and ultraviolet absorp-tions, Raman scattering and X-ray diffraction of magnetized water were greatly changed relative to those of pure water; their strengths of peaks were all increased, the frequencies of some peaks did also shift, and some new peaks, for example, at 5198, 8050 and 9340 cm?1, occurred at 25℃ after water was magnetized. In the meanwhile, the magnetized effects of water are related to the magnetized time, the intensity of an externally applied magnetic field, and the temperature of water, but they are not a linear relationship. The study also showed a lot of new and unusual properties of magnetized water, for example, the six peaks in 3000-3800 cm?1 in infrared absorption, the exponential increase of ultraviolet absorption of wave with the decreasing wavelength of light of 200-300 nm, the frequency-shifts of peaks, a strange irreversible effect in the increasing and decreasing processes, as well as a stronger peak of absorption occurring at 50℃, 70℃ and 80℃, the existence of many models of motion from 85℃ to 95℃ in 8000-10000 cm?1, and so on. These results show that the molecular structure of water is very complicated, which needs further study. Furthermore, the macroscopic feature of mechanics, for instance, surface tension force of magnetized water, was also measured. Experiments dis-covered that the size in contact angles of magnetized water on the surface of hy-drophobic materials decreases, thus the surface tension force of magnetized water decreases relative to that of pure water. It is seen from the above results that the clustering structure of hydrogen-bonded chains and polarization effects of water molecules are enhanced after magnetization. These results are helpful in revealing the mechanism of magnetization of water. | PANG XiaoFeng1,2 & DENG Bo1 1 Institute of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China 2 International Centre for Materials Physics, Chinese Academy of Sciences, Shenyang 110015, China | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，11： | 23 |
| 18 | Deep tectonic setting of the 2008 Wenchuan M_s8.0 earthquake in southwestern China―Joint analysis of teleseismic P-wave receiver functions and Bouguer gravity anomalies显示文摘Teleseismic P-wave receiver functions at 20 broadband seismic stations in the Longmenshan fault zone (LMFZ) and its vicinity were extracted, and the crustal thickness and the P- and S-wave velocity ratio were calculated by use of the H-k stacking algorithm. With the results as constraints, the S-wave ve-locity structures beneath each station were determined by the inversion of receiver functions. The crustal structure of the Rear-range zone is similar to that of the Songpan-Garze Block, whereas the velocity structure of the Fore-range zone resembles that of Sichuan Basin, implying that the Central Principal Fault of LMFZ is the boundary between the eastern Tibetan Plateau and the Yangtze Block. Lower velocity zone exists in lower crust of the Songpan-Garze Block and the central-southern seg-ment of the Rear-range zone, which facilitates the detachment of the material in upper and middle crust. Joint analysis of the receiver functions and the Bouguer gravity anomalies supports the thesis on the detachment-thrust mode of the LMFZ. A double-detachment pattern is suggested to the tectonic setting in the Songpan-Garze Block. The upper detachment occurs at the depth of 10-15 km, and represents a high-temperature ductile shear zone. There is a lower detachment at the depth of about 30 km, below which the lower crust flow exists in the eastern Tibetan Plateau. Interpretation of the Bouguer gravity anomalies indicates that the Sichuan Basin is of higher density in upper and middle crust in compari-son with that of the Songpan-Garze Block. The LMFZ with higher density is the result from the thrusting of the Songpan-Garze Block over the Sichuan Basin. In the lower crust, higher P velocity and higher density in the Sichuan Basin are related to more rigid material, while lower S velocity and lower density in the Songpan-Garze Block are related to the softened and weakened material. The higher density block beneath the Sichuan Basin obstructs the eastward flow of lower crustal material from the Tibetan Plateau, which is driven by the compression of northward movement of Indian Plate. The eastward movement of upper and middle crustal material is also obstructed by the rigid Yangtze Block, resulting in the stress concentrated and accumulated along the LMFZ. When the stress releases sharply, the Wenchuan Ms8.0 earthquake occurs. | LOU Hai1, WANG ChunYong1, L ZhiYong2, YAO ZhiXiang1, DAI ShiGui2 & YOU HuiChuan1 1 Institute of Geophysics, China Earthquake Administration, Beijing 100081, China 2 Earthquake Administration of Sichuan Province, Chengdu 610041, China | 2009 | Science China Earth Sciences2009，52，2： | 21 |
| 19 | The Uplift of the Longmenshan Thrust Belt and Subsidence of the West Sichuan Foreland Basin显示文摘Based on fission track dating of apatite, and measurement of vitrinite reflectance of rock samples from the Longmenshan (Longmen Mountain)area and the West Sichuan foreland basin and computer modelling it is concluded that (l)the Songpan-Garze fold belt has uplifted at least by 3-4 km with an uplift rate of no less than 0.3-0.4 mm/a since 10 Ma B.P.; (2) the Longmenshan thrust nappe belt has uplifted at least by 5-6 km with an uplift rate of more than 0.5- 0.6 mm /a since 10 Ma B.P.; (3) the Longmenshan detachment belt has uplifted by 1 - 2 km at a rate of 0.016-0.032 mm/a since 60 Ma B.P.; (4) the West Sichuan foreland basin has uplifted by 1.7-3 km at a rate of 0.028-0.05 mm/a since 60 Ma B.P.; (5) the uplift rate of the area on the west side of the Beichuan-Yingxiu-Xiaoguanzi fault for the last 10 Ma is 40 times as much as that on its east side; (6) the uplifting of the the Songpan - Garze fold belt and the subsidence of the West Sichuan foreland basin 60 Ma ago exhibit a mirro-image correlation, i. | Liu Shugen, Luo Zhili, Dai Sulan, Changlu Institute of Technology, Chengdu, Sichuan, ChinaDennis Arne Dalhousie U niversity, Canadaand C.J.L. Wilson Melbourne U niversity, Australia Jiang M inxi | 1996 | Acta Geologica Sinica(English Edition)1996，70，1： | 21 |
| 20 | Changed clinical aspects of primary liver cancer in China during the past 30 years显示文摘BACKGROUND: Primary liver cancer (PLC) is one of the most frequently seen tumors in China. Thirty years ago, patients with PLC were often detected at relatively late stage, with a palpable mass or marked clinical symptoms and poor prognosis. In the past 30 years, the diagnosis and treatment of PLC have been greatly improved with better prognosis. METHODS: In order to study the changes of PLC during the 30 years, the clinical data of 3250 patients with PLC from 10 medical institutions of China were collected, ana- lyzed , and compared with those of 3254 PLC patients be- fore the 30 years. RESULTS: In the 3250 patients aged 1-80 years, with an average age of 49.1 years, the male to female ratio (2.3:1) was lower than that before the 30 years. 73.5% of the 3250 patients sought medical advice within 3 months after the onset of the disease in contrast to 63.8% before the 30 years. Compared with those patients before the 30 years the symptoms and signs were alleviated generally. The HBsAg positive rate was 81.0%, but the HCV-Ab positive rate was 13.2%. The AFP level in 75% of patients was elevated, but in the remaining 25% was normal. 1912 patients (58.8%) were confirmed pathologically. Among them 1755 patients (91.8%) had hepatocellular carcinoma. The overall resec- tion rate was 46.3%. Those who had early, middle, late stage carcinoma accounted for 29.9%, 51.5%, and 18.6%respectively in contrast to 0.4%, 47.0%, and 52.6% repor- ted before the 30 years. The 1-, 3-, 5-year survival rates of the patients were 66.1%, 39.7%, and 32.5% respectively, whereas 93.5%, 70.1%, and 59.1% for the early stage pa- tients, and 65.3%, 30.5%, and 23.5% for the middle stage patients. The half and 1-year survival rates of the late stage patients were 52.5%, and 14.7%, respectively. CONCLUSION: Comparison with the clinical data before and after the 30 years show that PLC can be diagnosed ear- ly. More PLC patients tend to undergo resection while re- ceiving a better conservative treatment, which ensures a prognosis. | Bing-Hui Yang, Jing-Lin Xia, Li-Wen Huang, Zhao-You Tang, Ming-Shan Chen, Jin-Qing Li, An-Min Liang, Qin-Guo Mo, Hui-Shan Lu, Chao-Liu Dai, Lu-Nan Yan, Zhi-Jian Yu, Rong-Sheng Rao, Le-Qun Li, Zhi-Xiong Su, Zhuang-Wei Fang Shanghai, China Liver Cancer Institute & Zhongshan Hospital, Fudan University, Shanghai 200032, China Tumor Hospital, Zhongshan University, Guangzhou 510000, China Tumor Hospital, Guangxi Medical Universi- ty, Nanning 530000, China Xiehe Hospital, Fujian Medical University, Fuzhou 350000, China Second Hos- pital, Chinese Medical University, Shenyang 110000, China Huaxi Hospital, Sichuan University, Chengdu 610041, China Hospital Affiliated to Nantong Medical University, Nantong 226000 , China Second Hospital, Jiangxi Medical University, Nanchang 330000 , China First Hospital Affiliated to Guangxi Medical University, Nanning 530000 , China People’s Hospital of Hainan Province, Haikou 570000, China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，2： | 20 |
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