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| 1 | 高纤维膳食和补充乙酸盐改变肠道菌群,预防醋酸脱氧皮质酮-盐型高血压小鼠高血压和心力衰竭的发展显示文摘水果和蔬菜的膳食摄入与高血压的发生率较低有关,但所涉及的机制尚未阐明。该研究评估了高纤维膳食和短链脂肪酸(short-chain fatty acid,SCFA)(乙酸盐)对肠道微生物群和预防心血管病的影响。方法:用盐皮质激素诱发小鼠高血压模型,观测正常喂食组、高纤维喂食组和补充乙酸盐组的肠道微生物、心脏结构/功能和血压水平。 | 刘莉 叶鹏 Marques FZ Nelson EM Chu PY Horlock D Fiedler A Ziemann M Tan JK Kuruppu S Rajapakse NW El-Osta A Mackay CR Kaye DM | 2016 | 中华高血压杂志2016，24，12： | 8 |
| 2 | Age and menopausal status are important factors influencing the serum human epididymis secretory protein 4 level:a prospective cross-sectional study in healthy Chinese people显示文摘Background::Human epididymis secretory protein 4(HE4)is a new ovarian cancer biomarker.The factors influencing HE4 levels are not clear,and the reference data in China are limited.Here,we aim to evaluate the effects of menopause and age on HE4 levels and to provide a possible reference value for HE4 in healthy Chinese people.Methods::A total of 2493 healthy females aged 40 years or older were recruited from March 2013 to March 2017 with the cooperation of four medical institutions across Beijing,China.The serum levels of HE4 and cancer antigen 125(CA125)were measured by enzyme-linked immunosorbent assay.The Wilcoxon rank-sum test of variance and a stratified analysis were used to analyze the relationships among age,menopausal status,and levels of HE4 or CA125.Confidence intervals(5%-95%)were determined for reference ranges in different populations.Results::There was a statistically significant difference in median HE4 levels between the post-menopausal(n=2168)and premenopausal groups(n=325)(36.46 vs.24.04 pmol/L,Z=-14.41,P<0.001).HE4 increased significantly with age in the post-menopausal groups(H=408.18,P<0.001)but not in the pre-menopausal subjects(Z=-0.43,P=0.67).The upper 95th percentile of HE4 levels were 44.63 pmol/L for pre-menopausal women,78.17 pmol/L for post-menopausal women,and 73.3 pmol/L for all women.In the post-menopausal population,the HE4 reference ranges were 13.15 to 47.31,14.31 to 58.04,17.06 to 73.51,24.50 to 115.25,and 35.71 to 212.37 pmol/L for different age groups from forty divided by decade.The CA125 level was affected mainly by menopausal status and not age.Conclusions::Menopausal status and age were both important factors influencing the level of HE4,and age affected HE4 levels mainly in post-menopausal women.The HE4 level was higher in the post-menopausal population than in the pre-menopausal population and increased with age. | Hong-Yan Cheng Lin Zeng Xue Ye Rui-Qiong M a Zhi-Jian Tang Hong-Ling Chu Yi-M ing Zhao Li-Rong Zhu Yu-Nong Gao Xiao-Hong Chang Heng Cui | 2020 | Chinese Medical Journal2020，，11： | 6 |
| 3 | Soluble E-cadherin is a valid prognostic marker in gastric carcinoma显示文摘 | Chan A O Lam S K Chu K M | 2001 | Gut2001，48，6： | 2 |
| 4 | Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c - IAP2 is under NF-kappa B control 显示文摘 | Chu Z L Mckinsey T A Lia L Gentry J J Malim M H Ballard D W | 1997 | PNAS1997，94，10： | 1 |
| 5 | Synthesis and Character-ization of Multifunctional Periodic Mesoporous Organosilica fromDiureidophenylene Bridged Organosilica Precursor 显示文摘 | WAHAB M A CHU S W^ANAND C | 2012 | J NanosciNanotechno2012，12，6： | 1 |
| 6 | Total-energy study of electronic structure and mechanical behavior of C15 Laves phase compounds:NbCr2 and HfV2显示文摘 | Ormeci A Chu F Wills J M | 1996 | Physical Review B1996，54，12： | 1 |
| 7 | Determination of ponding condi- tion and infiltration into layered soils under unsteady rainfall 显示文摘 | Chu X Marino M A | 2005 | J Hydrol2005，313，34： | 1 |
| 8 | Increasing rates of cardiac device infections among medicare beneficiaries: 1990–1999显示文摘 | Christopher H Cabell Paul A Heidenreich Vivian H Chu Christopher M Moore Martin E Stryjewski G.Ralph Corey Vance G Fowler | 2004 | American Heart Journal2004，，4： | 1 |
| 9 | Multiple sources for the origin of granites: Geochemical and Nd/Sr isotopic evidence from the Gudaoling granite and its mafic enclaves, northeast China显示文摘 | Yang J H Wu F Y Chung S L Wilde S A Chu M F | 2004 | Geochim Cosmochim Acta2004，68，44： | 1 |
| 10 | Biosorption of cadmium by brown,green,and ted seaweeds显示文摘 | Hashim M A Chu K H | 2004 | Chemical Engineering Journal2004，97，： | 1 |
| 11 | Aerosol distribution in the Northern Hemisphere during ACE-Asia:results from global model,satellite observations,and sun photometer measurements显示文摘 | Chin M Chu A Levy R | 2004 | Journal of Geophysical Research:Atmospheres2004，109，： | 1 |
| 12 | Applica- tions of Digital-image-correlation Techniques to Ex- perimental Mechanics 显示文摘 | CHU T C RANSON W F SUTTON M A | 1985 | Experimental Mechanics1985，25，3： | 1 |
| 13 | Applications of digitalimage-correlation techniques to experimental mechanics显示文摘 | Chu T C Ranson W F Sutton M A | 1985 | Experimental Mechanics1985，25，3： | 1 |
| 14 | Gyrotron internal mode converter reflector shaping from measured field intensity显示文摘 | Denison D R Chu T S Shapiro M A | 1999 | IEEE Transactions on Plasma Science1999，27，2： | 1 |
| 15 | Evaluating the Performance of an Integrated Navigation System显示文摘 | Lorga J F M Chu Q P Mulder J A | 2005 | 2005，，： | 1 |
| 16 | Enriched elementfree Galerkin methods for crack-tip field 显示文摘 | Fleming M Chu Y A Organ B | 1997 | Int J Numer Meth Engng1997，，40： | 1 |
| 17 | Puhnonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection 显示文摘 | Numata M Chu H W Dakhama A | 2010 | Proc Natl Acad Sci2010，107，1： | 1 |
| 18 | Application of digital image correlation techniques to experimental mechanics显示文摘 | Chu T C Ranson W F Sutton M A | 1985 | Exp Mech1985，25，： | 1 |
| 19 | Deposition and Properties of Polycrystalline TiN/NbN Super- lattice Coatings 显示文摘 | Chu X Wong M S Barnett S A | 1992 | Journal of Vacuum Science and Technology1992，10，4： | 1 |
| 20 | Highly conductive PEDOT:PSS treated with formic acid for ITO-free polymer solar cells 显示文摘 | Mengistie D A Ibrahem M A Wang P C Chu C W | 2014 | ACS Applied Mate-rials Interfaces2014，6，4： | 1 |
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