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| 1 | Transcriptomic and metabolomic analyses of cucumber fruit peels reveal a developmental increase in terpenoid glycosides associated with age-related resistance to Phytophthora capsici显示文摘The oomycete,Phytophthora capsici,infects cucumber(Cucumis sativus L.)fruit.An age-related resistance(ARR)to this pathogen was previously observed in fruit of cultivar‘Vlaspik’and shown to be associated with the peel.Young fruits are highly susceptible,but develop resistance at~10–12 days post pollination(dpp).Peels from resistant(16 dpp)versus susceptible(8 dpp)age fruit are enriched with genes associated with defense,and methanolic extracts from resistant age peels inhibit pathogen growth.Here we compared developing fruits from‘Vlaspik’with those of‘Gy14’,a line that does not exhibit ARR.Transcriptomic analysis of peels of the two lines at 8 and 16 dpp identified 80 genes that were developmentally upregulated in resistant‘Vlaspik’16 dpp versus 8 dpp,but not in susceptible‘Gy14’at 16 dpp.A large number of these genes are annotated to be associated with defense and/or specialized metabolism,including four putative resistance(R)genes,and numerous genes involved in flavonoid and terpenoid synthesis and decoration.Untargeted metabolomic analysis was performed on extracts from 8 and 16 dpp‘Vlaspik’and‘Gy14’fruit peels using Ultra-Performance Liquid Chromatography and Quadrupole Time-of-Flight Mass Spectrometry.Multivariate analysis of the metabolomes identified 113 ions uniquely abundant in resistant‘Vlaspik’16 dpp peel extracts.The most abundant compounds in this group had relative mass defects consistent with terpenoid glycosides.Two of the three most abundant ions were annotated as glycosylated nor-terpenoid esters.Together,these analyses reveal potential mechanisms by which ARR to P.capsici may be conferred. | Ben N Mansfeld Marivi Colle Yunyan Kang A Daniel Jones Rebecca Grumet | 2017 | Horticulture Research2017，4，1： | 3 |
| 2 | Gene therapy of the brain in the dog model of Hurler' s ayndrome显示文摘 | Ciron C Desmaris N Colle MA | 2006 | Ann Neurol2006，60，2： | 1 |
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| 4 | Flow patterns in an ul- trasonic liquid flow meter显示文摘 | Emperley N C Behnia T M Collings A F | 2000 | Flow Measurement and Instrumen- tation2000，11，： | 1 |
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| 6 | Normal ureter size on unenhanced helical CT显示文摘 | Zelenko N Coll D Rosenfeld AT | 2004 | AJR2004，182，4： | 1 |
| 7 | The effective density and fractal dimension of particles emitted from a light - duty diesel ve- hicle with a diesel oxidation catalyst 显示文摘 | Olfert J S Symonds J P R Collings N | 2007 | Journal of Aerosol Sci- ence2007，38，26： | 1 |
| 8 | Ultrafine particles in the atmosphere: Introduction显示文摘 | Brown LM Collings N Harrison RM | 2000 | Philos Trans R Soc Lond A2000，358，： | 1 |
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| 10 | Sequence typing confirms that Campylobacterjejuni strains associated with Guillain-Barre' and Miller Fisher syndromes are of diverse genetic lineage, serotype, and flagella type显示文摘 | DINGLE K E VAN DEN BRAAK N COLLES F M | 2001 | J Clin Microbiol2001，39，： | 1 |
| 11 | Agent-based modeling - intelligent customer relationship management显示文摘 | N Baxter D Collings I Adjali | 2003 | BT Technology Journal2003，，2： | 1 |
| 12 | Cell death and cancer:replacement of apoptotic genes and inactivation of death suppressor genes in therapy显示文摘 | Coll JL Louis N | 1998 | Gene Ther1998，5，6： | 1 |
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| 15 | Erosion of metals by fly ash particle显示文摘 | YEE K H SHAYLER P J COLLINGS N | 1983 | Wear1983，，91： | 1 |
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| 17 | Melittin-loaded immunoliposomes against viral surface proteins, a new approach to antiviral therapy显示文摘 | Alberto Falco Enrique Barrajón-Catalán María P. Menéndez-Gutiérrez Julio Coll Vicente Micol Amparo Estepa | 2012 | Antiviral Research2012，，： | 1 |
| 18 | Increased circulating endothelial microparticles in COPD显示文摘 | García J Del Pozo R Coll N | 2013 | Eur Respir J2013，42，57： | 1 |
| 19 | Gasoline fuelled partially premixed compression ignition in a light duty multi cylinder en- gine:a study of low load and low speed operation显示文摘 | Weall A Collings N | 2009 | SAE Paper2009，，： | 1 |
| 20 | Unipolar diffusion charging of aerosol particles in the transition regime 显示文摘 | Biskos G Reavell K Collings N | 2005 | Journal of Aerosol Science2005，36，： | 1 |
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