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| 1 | Helicobacter pylori recurrence after eradication in Latin America:Implications for gastric cancer prevention显示文摘AIM To estimate Helicobacter pylori(H. pylori) recurrence rate in Latin America, a region with a significant H. pylori prevalence and gastric cancer burden.METHODS Pub Med, LILACS, Sci ELO, Cochrane databases and abstracts from relevant meetings were reviewed. Information collected included: Participants' characteristics, recruitment strategy, diagnostic modality, treatment arms, follow-up and recurrence rates. Recurrence was calculated using 100-patients-year rates, and data were pooled using a random effects model. The I2 statistic assessed between study heterogeneity. Meta-regression analyses evaluated for effect modifying variables. RESULTS Literature search yielded 163 articles. Twelve studies involving 4848 patients from 9 countries met inclusion criteria. Four hundred and thirty-two reinfections were recorded in 5487 person-years of follow-up. Pooled analysis showed a recurrence rate of 7.9 cases per 100 person-years(95%CI: 5.3-10.5). Meta-regression revealed that neither the antibiotic schema, a second antibiotic course, nor the diagnostic modality had an impact on the observed risk of recurrence. The recurrence rate in the first year after treatment, predominantly recrudescence,was 11.2(6.1-16.4) per 100 patient years. Recurrence in subsequent years, was only 6.2(3.8-8.7).CONCLUSION H. pylori recurrence rates in Latin America are significant, and with geographic variability, yet are acceptable based upon the current literature for consideration of large scale intervention trials. Further research in Latin America is warranted to evaluate the efficacy, cost-effectiveness, and potential adverse outcomes of proposed eradication programs. | Juan E Corral Robertino Mera Corey W Dye Douglas R Morgan | 2017 | World Journal of Gastrointestinal Oncology2017，9，4： | 5 |
| 2 | Enantioselective Iotal synthe sis of ecteinascidin 743显示文摘 | Corey E J Gin D Y Kania R S | 1996 | J Am Chem Soc1996，118，38： | 1 |
| 3 | Nemo-like kinase induces apoptosis and inhibits androgen receptor signaling in prostate cancer cells显示文摘 | Emami K H Brown L G Pitts T E Sun X Vessella R L Corey E | 2009 | Prostate2009，69，： | 1 |
| 4 | A simple stereocontrolled synthesis of salinosporamide A 显示文摘 | Reddy L R Saravanan P Corey E J | 2004 | J Am Chem Soc2004，126，： | 1 |
| 5 | Placebo-controlled trial of vaccination with recombinant glycoprotein d of herpes simplex virus type 2 for immunotherapy of genital herpes显示文摘 | STRAUS S E COREY L BURKE R L | 1994 | Lancet1994，343，8911： | 1 |
| 6 | Calculation of hydraulic conductivity : a further evaluation of some predictive methods 显示文摘 | GREEN R E COREY J C | 1971 | Soil Science Society of America Proceedings1971，35，1： | 1 |
| 7 | Coumarome(benzofuran)显示文摘 | COREY E J BENSON R E | 1966 | Org Synth1966，46，： | 1 |
| 8 | Pulmonary function and clinical course in patients with cystic fibrosis after pulmonary coloni- zation with Pseudomonas aeruginosa 显示文摘 | Kerem E Corey M Gold R Levison H | 1990 | J Pediatr1990，116，5： | 1 |
| 9 | An investigation of the structureof silk fibroin显示文摘 | Marsh R E Corey R B Pauling L | 1955 | Biochim Biophy Acta1955，，16： | 1 |
| 10 | Enantioselective total synthesis of ecteinascidin 743 显示文摘 | Gin D Y Kania R S | 1996 | J Am Chem Soc1996，118，： | 1 |
| 11 | Evidence in favor of an organoiron-mediated pathway for lipoxygenation of fatty acids by soybean lipoxygenase 显示文摘 | Corey E J Nagata R | 1987 | Journal of the American Chemical Society1987，109，26： | 1 |
| 12 | Photoionization of the excited 3p state of sodium: experiment and theory显示文摘 | PRESES J M BURKHARDT C E COREY R L | 1985 | Phys Rev A1985，32，： | 1 |
| 13 | An efficient and catalytically enantioselective route to (S) - ( - ) - phenyloxirane 显示文摘 | COREY E J SHIBATA S BAKSHI R K | 1988 | J OrgChem1988，53，12： | 1 |
| 14 | Calculation of Hydraulic Conductivity: A Further Evaluation of Some Predictive Method显示文摘 | Green R E and Corey J C | 1971 | Soil Science Society of America Proceedings1971，35，： | 1 |
| 15 | 显示文摘 | COREY E R DAHL L F | 1961 | J Am Chem Soc1961，83，： | 1 |
| 16 | Crystalline regions of Bomyx mori silk fibroin may exhibit turn and helix conformation显示文摘 | R E Marsh R B Corey L Pauling | 1975 | Biochemica Biophysica Acta1975，16，1： | 1 |
| 17 | Giant Magnetoresistance in Heterogeneous Cu-Co Alloys显示文摘 | BERKOWITZ A E MITEKELL J R COREY M J | 1992 | Phys Rev Lett1992，68，： | 1 |
| 18 | Enantioselective total synthesis of Ecteinascidin-743 显示文摘 | Corey E J Gin D Y Kania R S | 1996 | J Am Chem Soc1996，118，： | 1 |
| 19 | Practical enantioselective die Ls-alder and aldol reactions using a new chiral controller system 显示文摘 | Corey E J Imwinkelried R Pikul S | 1989 | J Am Chem Soc1989，111，14： | 1 |
| 20 | Sterospecific elaboration of a ring of Gibberellic acid by partial synthesis 显示文摘 | COREY E J BRENNAN T M CARNEY R L | 1971 | J Am Chem SOc1971，53，： | 1 |
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