维普中文期刊产品整合服务
72篇 您的检索式:作者名="Cornwall A"
    题名 作者 年代 出处 被引量
1胱蛋白酶抑制剂相关的附睾精子发生基因的调节和功能显示文摘CRES(cystatin relatedepididymalspermatogenic,胱蛋白酶抑制剂相关的附睾精子发生 )蛋白是胱蛋白酶抑制剂(cystatin)超家族中家族 2的一个亚类。然而 ,与cystatinC的广泛性表达不同 ,Cres基因只在分裂后的生殖细胞、附睾头部近端和腺垂体促性腺激素细胞中表达。cystatin对C1半胱氨酸蛋白酶抑制作用的发挥必须有 3个共有位点的参与 ,而CRES蛋白缺少其中的 2个位点。因此 ,CERS在生殖系统和神经内分泌系统中的功能也许是独特的和组织特异性的。本文概述了以下方面的研究 :①Cres基因启动子及其转录调节蛋白相关的可能对Cres的组织特异性表达有重要作用的DNA结合位点。②CRES蛋白的生物学功能。Norethern印迹法、凝胶转移分析和瞬时转染实验均表明 ,附睾和促性腺激素细胞中主要表达C EBP家族中的C EBPβ(CCAAT 增强子结合蛋白 ) ,且C EBPβ对于Cres基因在这两个组织中的高表达是必不可少的。另外 ,构建了表达氯霉素乙酰基转移酶 (CAT)报告基因的转基因小鼠 ,CAT报告基因由Cres基因 5′端 1 6kb的启动子所调控。分析显示 ,CATmRNA仅在生殖细胞中表达 ,说明Cres 5′端 1 6kb的侧翼区含有调控CAT在睾丸中表达的DNA序列 ,而缺乏指导CAT在附睾中表达的序列 ,或者此1 6kb的DNA片段存在Cres的负调节成分。最后 ,Gail A CORNWALL Nelson HSIA 2002中华男科学杂志2002,8,5:2
2The S100 pro- tein family:history,function and expression 显示文摘Zimmer DB Cornwall EH Landar A 1995Brain Red Bull1995,37,4:1
3Introduction:Accountability through participation:Developing workable partnership models in the health sector显示文摘Cornwall· A Lucas· H & Pasteur· K 2000IDS Bulletin2000,31,:1
4A nuclear warhead with a cooled shroud 显示文摘Sessler A M Cornwall J M Dietz B 2004Countermeasures2004,4,:1
5Biomeehanical evaluation of stand alone lumbar poly- ether-ether-ketone interbody cage with integrated screws显示文摘KORNBLUM M B TURNER A W L CORNWALL G B 2013The Spine Journal2013,13,1:1
6The SIO0 protein family: history, function, and expression 显示文摘Zimmer DB Cornwall EH Landar A 1995Brain Res Bull1995,37,:1
7Cystatin-related epididymal spermatogenic protein colocalizes with luteinizing hormone-beta protein in mouse anterior pituitary gonadotropes显示文摘Sutton HG Fusco A Cornwall GA 1999Endocrinology1999,140,6:1
8Furanodecalin synthesis using intramolecular Diels-Alder reactions of vinylfurans 显示文摘Cooper J A Cornwall P Dell C P 1988Tetrahedron Letters1988,29,17:1
9The S-100 protein family:history,function and expression显示文摘Zimmer DB Cornwall EH Landar A 1995Brain Res Bull1995,37,4:1
10The S100 protein family: history, function, and expression 显示文摘Zimmer DB Cornwall EH Landar A 1995Brain Res Bull1995,37,4:1
11Discussion of Denison显示文摘Colm G Cornwall J Smithies A 1962American Economic Review1962,52,2:1
12The S100 pro- tein family: history, function, and expression 显示文摘Zimmer DB Cornwall EH Landar A 1995Brain Res Bun1995,37,4:1
13The S2100 protein family:history,function and expression显示文摘 Cornwall EH Landar A 1995Brain Res Bull1995,37,:1
14The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2 显示文摘Cornwall GA Cameron A Lindberg I 2003Endocrinology2003,144,3:1
15The S100 protein family: history,function, and expression显示文摘 Cornwall EH Landar A 1995Brain Res Bull1995,37,4:1
16The S100 protein family:history function and expression显示文摘Zimmer D Cornwall Z Lander A 1995Brain Ras Bull1995,37,:1
17Bridging the Gap: Citizen- ship, Participation and Accountability 显示文摘CORNWALL A GAVENTA J 2001PLA Notes2001,40,1:1
18The relationship between phonological awareness and reading and spelling achievement eleven years later显示文摘MACDONALD G CORNWALL A 1995Journal of Learning Disabilities1995,,:1
19A New Members of the CRES Subgroup of Family 2 Cystatins 显示文摘HSIA N CORNWALL G A 2003Molecular and Cellular Endocrinology2003,200,:1
20The S100 protein family history, function, and expression显示文摘Zimmer DB Cornwall EH Landar A 1995Brain Res Bull1995,37,4:1
返回顶部 每页显示:
共4页 首页 上一页 第1页 下一页 末页 /4 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费