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237篇 您的检索式：作者名="Costa T R"

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	题名	作者	年代	出处	被引量
1	Relevance of MUC1 mucin variable number of tandem repeats polymorphism in H pylori adhesion to gastric epithelial cells显示文摘AIM:To evaluate the influence of MUC1 mucin variable number of tandem repeats (VNTR) variability on H pylori adhesion to gastric cells. METHODS: Enzyme linked immunosorbent assay (ELISA)-based adhesion assays were performed to measure the adhesion of different H pylori strains (HP26695 and HPTx30a) to gastric carcinoma cell lines (GP202 and MKN45) and GP202 clones expressing recombinant MUC1 with different VNTR lengths. RESULTS: Evaluation of adhesion results shows that H pylori pathogenic strain HP26695 has a significantly higher (P < 0.05) adhesion to all the cell lines and clones tested, when compared to the non-pathogenic strain HPTx30a. Bacteria showed a significantly higher (P < 0.05) adhesion to the GP202 cell line, when compared to the MKN45 cell line. Furthermore, both strains showed a significantly higher (P < 0.05) adhesion to GP202 clones with larger MUC1 VNTR domains. CONCLUSION: This work shows that MUC1 mucin variability conditions H pylori binding to gastric cells. The extent of bacterial adhesion depends on the size of theMUC1 VNTR domain. The adhesion is further dependent on bacterial pathogenicity and the gastric cell line. MUC1 mucin variability may contribute to determine H pylori colonization of the gastric mucosa.	Natália R Costa Nuno Mendes Nuno T Marcos Celso A Reis Thomas Caffrey Michael A Hollingsworth Filipe Santos-Silva	2008	World Journal of Gastroenterology2008，14，9：	4
2	Role of myofibroblasts, macrophages, transforming growth factor-beta endothelin, angiotensin- Ⅱ , and fibronectin in the progression of tubulointerstitial nephritis induced by gentamicin 显示文摘	Geleilete T J Melo G C Costa R S	2002	J Nephrol2002，15，6：	1
3	An Introduction to the Five-factor Model and its Applications 显示文摘	McCrae R R Costa P T	1992	Journal of Personality1992，60，2：	1
4	Ulcerative and nonulcerative forms of bladder pain syndrome/interstitial cystitis do not dif- fer in symptom intensity or response to onabotulinum toxin A 显示文摘	Pinto R Lopes T Costa D	2014	Urology2014，83，5：	1
5	Influence of Extraversion Subjective Well-being:Happy and Unhappy People显示文摘	McCrac R R	1980	Journal of Per-sonality and Social psychology1980，38，4：	1
6	Personality trait structure as a human universal显示文摘	MCCRAER R COSTA P T	1997	American Psychologist1997，52，5：	1
7	Clinical features and outcome of patiens with non-small-cell lung cancer who harbor EML4-ALK显示文摘	Shaw A T Yeap B Y Mino-Kenudson M Digumarthy S R Costa D B Heist R S	2009	J Clin Oncol2009，27，：	1
8	Influence of extraversion and neuroticism on subjective well-being: happy and unhappy people显示文摘	Costa P T McCrae R R	1980	Journal of personality and social psychology1980，38，4：	1
9	Protective effect of quercetin on the evolution of cisplatin-induced acute tubular necrosis显示文摘	FRANCESCATO H D C COIMBRA T M COSTA R S	2004	Kidney and Blood Pressure Research2004，27，3：	1
10	Ulcerative and nonulcerativeforms of bladder pain syndrome/interstitial cystitis do not differ insymptom intensity or response to onabotulinum toxin A 显示文摘	Pinto R Lopes T Costa D	2014	Urology2014，83，：	1
11	Pigments in the fruit of red-fleshed kiwifruit (Actinidia chinensis and Actinidia deliciosa) 显示文摘	Montefiori M McGhie T K Costa G Ferguson A R	2005	J Agric Food Chem2005，53，24：	1
12	Synthesis of aNiFe204 catalyst for the preferential oxidation of carbon monoxide (PROX)显示文摘	SANTOS P T A COSTA A C F M KIMINAMI R H G A ANDRADE H M C LIRA H L GAMA L	2009	Journal of Alloy and Compounds2009，483，12：	1
13	Validation of the five - factor model of personality across instruments and observers 显示文摘	MCCRAE R R COSTA P T JR	1987	J Pers Soc Psychol1987，52，1：	1
14	Ulcerative and nonulcer-ative forms of bladder pain syndrome/interstitial cystitis do not dif-fer in symptom intensity or response to onabotulinum toxin A显示文摘	PINTO R LOPES T COSTA D	2014	Urology2014，83，5：	1
15	Four ways five factors are basic 显示文摘	Costa P T McCrae R R	1992	Personality and Individual Differences1992，13，：	1
16	Highly ac tive new α - diimine nickel catalyst for the polymeriza- tion of a- Olefins显示文摘	LIU H R GOMES P T COSTA S I	2005	Journal of Organometallic Chemistry2005，690，：	1
17	Updating norman's adequate taxonomy' : Intelligence and personality dimensions in natural language and in questionnaires显示文摘	MCCRAE R R COSTA JR P T	1985	J Personality Soc Psyehol1985，，49：	1
18	Influence of extraversion and neuroticism on subjective well-being:happy and unhappy people显示文摘	Costa P T McCrae R R		0，，04：	1
19	Influence of extraversion and neuroticism on subjective Well-being:happy and unhappy people显示文摘	Costa P T Mccyae R R	1980	Journal of Personality and Social Psychology1980，38，4：	1
20	Adding Liebe and Arbeit: The Full Five-Factor Model and Well-being显示文摘	McCreae R R Costa P T	1991	Personality and Social Psychology Bulletin1991，17，2：	1

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