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53篇 您的检索式:作者名="Curmi"
    题名 作者 年代 出处 被引量
1Myosin binding protein C:Structural abnormalities in familial hypertrophic cardiomyopathy显示文摘The muscle protein myosin binding protein C (MyBPC) is a large multi-domain protein whose role in the sarcomere is complex and not yet fully understood. Mutations in MyBPC are strongly associated with the heart disease familial hypertrophic cardiomyopathy (FHC) and these experiments of nature have provided some insight into the intricate workings of this protein in the heart. While some regions of the MyBPC molecule have been assigned a function in the regulation of muscle contraction, the interaction of other regions with various parts of the myosin molecule and the sarcomeric proteins, actin and titin, remain obscure. In additic n, several intra-domain interactions between adjacent MyBPC molecules have been identified. Although the basic structure of the molecule (a series of immunoglobulin and fibronectin domains) has been elucidated, the assembly of MyBPC in the sarcomere is a topic for debate. By analysing the MyBPC sequence with respect to FHC-causing mutations it is possible to identify individual residues or regions of each domain that may be important either for binding or regulation. This review looks at the current literature, in concert with alignments and the structural models of MyBPC, in an attempt to understand how FHC mutations may lead to the disease state.Cecily E OAKLEY Brett D HAMBLY Paul MG CURMI Louise J BROWN 2004Cell Research2004,14,2:2
2Overexpression of stathmin in breast carcinomas points out to highly proliferative tumours显示文摘Curmi PA Nogues C Lachkar S 2000Br J Cancer2000,82,1:1
3The role of macrofaunain the transformation and reversibility of soil structure of an Ox-isol in the process of forest to pasture conversion 显示文摘Barros E Curmi P Hallaire V 2001Geoder-ma2001,100,12:1
4Insight into tubulin regulation from a complex with colchicines and a stathmin-like domain显示文摘Ravelli R B G Gigant B Curmi P A 2004Nature2004,428,:1
5Overexpression of stathmin in breast carcinomas points out to highly proliferative tumours 显示文摘Curmi PA Nogues C Lachkar S 2000Br J Cancer2000,82,:1
6Stathmin: A tubulin--sequestering protein which forms a ternary T2S complex with two tubulin molecules显示文摘Jourdain L Curmi P Scbel A 1997J Biochem1997,36,10:1
7Phosphorylation of the tubulin-binding protein,stathmin,by Cdk5 and MAP kinases in the brain显示文摘 SOBEL A CURMI P A 2006J Neurochem2006,99,1:1
8Stathmin family proteins display specific molecular and tubulin binding properties显示文摘Charbaut E Curmi PA Ozon S 2001J Biol Chem2001,276,16:1
9Insight into tubulin regulation from a complex with eolchieine and a stathminlike domain显示文摘Ravelli RBG Gigant B Curmi PA 2004Nature2004,428,6979:1
10Combining geophysical methods to estimate the spatial distribution of soils affected by water saturation显示文摘Vincent Chaplot Christian Walter Pierre Curmi 2004Geoscience2004,336,:1
11Stathmin family proteins display specific molecular and tubulin binding properties 显示文摘CHARBAUT E CURMI P A OZON S 2001J Biol Chem2001,276,16:1
12The stathmin/tubulin interaction invitro显示文摘Curmi PA Andersen SS Lachkar S 1997J Biol Chem1997,272,25:1
13The stathmin-tubulin interaction and the regulation of the microtubule assembly显示文摘 Martin-Barbey C Curmi PA 2003Pathol Biol2003,51,1:1
14Earthworm activity and soil structure changes due to organicenrichments in vineyard systems显示文摘Pérès G Clnzeau D Curmi P 1998Biol Fertil Soils1998,27,:1
15An analysis of side chain interactions and pair correlations within antiparallel beta sheets: the differences between backbone hydrogen-bonded and non-hydrogen bonded residue pairs显示文摘Wouters MA Curmi PMG 1994Protein Sci1994,3,:1
16Overexpression of Stathminin in breast careinomas points out to highly proliferative tumours显示文摘Curmi P A Nogues C Lachkar S 2000Br J Cancer2000,82,1:1
17Mapping fieldscale hydromor-phic horizons using Radio-MT electrical resistivity显示文摘CHAPLOT V WALTER C CURMI P 2001Geoderma2001,102,:1
18Cold stress response in Archaea 显示文摘Cavicchioli R Thomas T Curmi PMG 2000Extremophiles2000,4,:1
19The stathmin/tubulin interaction in vitro 显示文摘CURMI PA ANDERSEN SS LACHKAR S 1997J Biol Chem1997,272,25:1
20Improving soil hydromorphy prediction according to DEM resolution and available pedological data显示文摘Chaplot V Walter C Curmi P 2000Geoderma2000,97,:1
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