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106篇 您的检索式:作者名="DENISE K"
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1Current concepts in the management of radial head fractures显示文摘Fracture of the radial head is a common injury. Over the last decades, the radial head is increasingly recognized as an important stabilizer of the elbow. In order to maintain stability of the injured elbow, goals of treatment of radial head fractures have become more and more towards restoring function and stability of the elbow. As treatment strategies have changed over the years, with an increasing amount of literature on this subject, the purpose of this article was to provide an overview of current concepts of the management of radial head fractures.Iza?k F Kodde Laurens Kaas Mark Flipsen Michel PJ van den Bekerom Denise Eygendaal 2015World Journal of Orthopedics2015,6,11:9
2Concordance of non-invasive mechanical and serum tests for liver fibrosis evaluation in chronic hepatitis C显示文摘AIM To determine the sensitivity and specificity of liver stiffness measurement(LSM) and serum markers(SM) for liver fibrosis evaluation in chronic hepatitis C.METHODS Between 2012 and 2014,81 consecutive hepatitis C virus(HCV) patients had METAVIR score from liver biopsy compared with concurrent results from LSM [transient elastography(TE) [FibroS can~/ARFI technology(Virtual Touch~)] and SM [FIB-4/aspartate aminotransferase-toplatelet ratio index(APRI)].The diagnostic performance of these tests was assessed using receiver operating characteristic curves.The optimal cut-off levels of each test were chosen to define fibrosis stages F ≥ 2,F ≥ 3 and F = 4.The Kappa index set the concordance analysis.RESULTS Fifty point six percent were female and the median age was 51 years(30-78).Fifty-six patients(70%) weretreatment-na?ve.The optimal cut-off values for predicting F ≥ 2 stage fibrosis assessed by TE were 6.6 kP a,for acoustic radiation force impulse(ARFI) 1.22 m/s,for APRI 0.75 and for FIB-4 1.47.For F ≥ 3 TE was 8.9 kP a,ARFI was 1.48 m/s,APRI was 0.75,and FIB-4 was 2.For F = 4,TE was 12.2 kP a,ARFI was 1.77 m/s,APRI was 1.46,and FIB-4 was 3.91.The APRI could not distinguish between F2 and F3,P = 0.92.The negative predictive value for F = 4 for TE and ARFI was 100%.Kappa index values for F ≥ 3 METAVIR score for TE,ARFI and FIB-4 were 0.687,0.606 and 0.654,respectively.This demonstrates strong concordance between all three screening methods,and moderate to strong concordance between them and APRI(Kappa index = 0.507).CONCLUSION Given the costs and accessibility of LSM methods,and the similarity with the outcomes of SM,we suggest that FIB-4 as well as TE and ARFI may be useful indicators of the degree of liver fibrosis.This is of particular importance to developing countries.Denise C Paranaguá-Vezozzo Adriana Andrade Daniel F C Mazo Vinicius Nunes Ana L Guedes Taisa G Ragazzo Renata Moutinho Lucas S Nacif Suzane K Ono Venancio A F Alves Flair J Carrilho 2017World Journal of Hepatology2017,9,8:7
3Implementation of a Pediatric Emergency Triage System in Xiamen, China显示文摘Gang-Xi Lin Yin-Ling Yang Denise Kudirka Colleen Church Collin K K Yong Fiona Reilly Qi-Yi Zeng 2016Chinese Medical Journal2016,,20:7
4Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models显示文摘AIM To assess the performance of BALAD, BALAD-2 and their component biomarkers in predicting outcome of hepatocellular carcinoma(HCC) patients after liver transplant.METHODS BALAD score and BALAD-2 class are derived from bilirubin, albumin, alpha-fetoprotein(AFP), Lens culinaris agglutinin-reactive AFP(AFP-L3), and des-gammacarboxyprothrombin(DCP). Pre-transplant AFP, AFP-L3 and DCP were measured in 113 patients transplanted for HCC from 2000 to 2008. Hazard ratios(HR) for recurrence and death were calculated. Univariate and multivariate regression analyses were conducted. C-statistics were used to compare biomarker-based to predictive models. RESULTS During a median follow-up of 12.2 years, 38 patients recurred and 87 died. The HRs for recurrence in patients with elevated AFP, AFP-L3, and DCP defined by BALAD cut-off values were 2.42(1.18-5.00), 1.86(0.98-3.52), and 2.83(1.42-5.61), respectively. For BALAD, the HRs for recurrence and death per unit increased score were 1.48(1.15-1.91) and 1.59(1.28-1.97). For BALAD-2, the HRs for recurrence and death per unit increased class were 1.45(1.06-1.98) and 1.38(1.09-1.76). For recurrence prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs. 0.64, 0.61, 0.53, and 0.53 for BALAD, BALAD-2, Milan, and UCSF, respectively. Similarly, for death prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs 0.65,0.61, 0.52, and 0.50 for BALAD, BALAD-2, Milan, and UCSF. A new model combining biomarkers with tumor size at the time of transplant(S-LAD) demonstrated the highest predictive capability with c-statistics of 0.71 and 0.69 for recurrence and death. CONCLUSION BALAD and BALAD-2 are valid in transplant HCC patients, but less predictive than the three biomarkers in combination or the three biomarkers in combination with maximal tumor diameter(S-LAD).Nicha Wongjarupong Gabriela M Negron-Ocasio Roongruedee Chaiteerakij Benyam D Addissie Essa A Mohamed Kristin C Mara William S Harmsen J Paul Theobald Brian E Peters Joseph G Balsanek Melissa M Ward Nasra H Giama Sudhakar K Venkatesh Denise M Harnois Michael R Charlton Hiroyuki Yamada Alicia Algeciras-Schimnich Melissa R Snyder Terry M Therneau Lewis R Roberts 2018World Journal of Gastroenterology2018,24,12:5
5Phoenixin: uncovering its receptor, signaling and functions显示文摘Phoenixin (PNX ) 是被连接了到繁殖功能的最新发现的肽,两个在视下丘和垂体。这评论将集中于与这新奇 neuropeptide 有关的最近的发现。开始, PNX 增加了释放刺激的荷尔蒙(GnRH ) 的 gonadotropin,这被发现从垂体房间的 luteinizing 荷尔蒙(LH ) 版本。重要地,在扩大的雌老鼠的 PNX 击倒到 2.3 天的动情期的周期。用新奇 hypothalamic 房间线,我们发现 PNX 在 kisspeptin (吻) 和 GnRH 基因表示和分泌物上有一个 stimulatory 角色。PNX 受体用 GPR173 击倒的 siRNA 被揭开,孤儿受体要求了绑 PNX。我们发现了在 hypothalamic 神经原通过蛋白质 kinase A (PKA ) 发信号的 PNX-R。很多研究表明的 Althuogh 那 PNX 在繁殖功能起一个重要作用,也有证据,它可以有另外的功能,调整心,喂,记忆,和焦虑,两个在大脑和圆周。Emma K MCILWRAITH Denise D BELSHAM 2018Acta Pharmacologica Sinica2018,39,5:4
6Wavefront-optimized surface retreatments of refractive error following previous laser refractive surgery: a retrospective study显示文摘Background:Retreatments are sometimes necessary to correct residual or induced refractive errors following refractive surgery.Many different combinations of primary treatment methods and retreatment techniques have been studied,however,few studies have investigated wavefront-optimized(WFO)technology for retreatment following primary refractive surgery.This study aimed to report the outcomes of WFO photorefractive keratectomy(PRK)retreatments of refractive error following previous laser refractive surgery with PRK,laser in situ keratomileusis(LASIK),or laser-assisted subepithelial keratectomy(LASEK).Methods:We reviewed records of patients who underwent WFO PRK retreatments using the Allegretto Wave Eye-Q 400 Hz Excimer Laser System(Alcon Surgical)between January 2008 and April 2011 at Walter Reed Army Medical Center and Madigan Army Medical Center.Outcomes were recorded in terms of uncorrected distance visual acuity(UDVA),manifest refraction spherical equivalent(MRSE),corrected distance visual acuity(CDVA),and complications at 1 month(M),3 M,and 6 M post-op.Results:Seventy-eight patients(120 eyes)underwent WFO PRK retreatment during the study period.Primary surgery was surface ablation in 87 eyes(78 PRK,9 LASEK)and LASIK in 33 eyes.The mean spherical equivalent before retreatment was−0.79±0.94 D(−3.00 to 1.88 D).UDVA was≥20/20 in 69 eyes(60.0%)at 1 M,54 eyes(71.1%)at 3 M,and 27 eyes(73.0%)at 6 M follow-up.MRSE was within±0.50 D of emmetropia in 78 eyes(67.8%)at 1 M,59 eyes(77.6%)at 3 M,and 25 eyes(67.6%)at 6 M follow-up.CDVA was maintained within±1 line of pre-op in 113 of 115 eyes(98.3%)at 1 M,74 of 76 eyes(97.4%)at 3 M,and 37 eyes(100%)at 6 M follow-up.Conclusion:Although follow-up was limited beyond 3 M,WFO PRK retreatments in patients with residual refractive error may be a safe and effective procedure.Further studies are necessary to determine the long-term safety and stability of outcomes.Kevin M.Broderick Rose K Sia Denise S.Ryan Richard D.Stutzman Michael J.Mines Travis C.Frazier Mark F.Torres Kraig S.Bower 2016Eye and Vision2016,3,1:3
7Correlation between water diffusion and adhesion loss: Study of an epoxy primer on steel显示文摘Elise Legghe Emmanuel Aragon Léna?k Bélec André Margaillan Denis Melot 2009Progress in Organic Coatings2009,,3:2
8Predicting wood decay in Eucalypts using an expert system and the IMLResistograph drill显示文摘Denise M J Peter K A Gregory M M 2007Arboriculture & Urban Forestry2007,32,2:1
9Diallielic single-stranded conformational polymorphism detected in the bovine prolactin gene显示文摘Zhang H M Denise S K Ax R L 1994J Anim Sci1994,72,1:1
10Toward a the of organization culture and effectiveness显示文摘Denision D R Mishra A K 0,,:1
11Power of Exclusion for Parentage Verification and Probability of Match for Identity in American Kennel Club Breeds Using 17 Canine Microsatellite Markers显示文摘DeNise E Johnston J H alverson K 2004Animal Genet2004,35,1:1
12A novel polymor- phism in the bovine insulin-like growth factor binding protein-3 (IGFBP-3) gene显示文摘MACIULLA J H ZHANG H M DENISE S K 1997Anita Genet1997,28,:1
13Bioaccumulation and enhanced persistence of the acaricide dicofol by Azospirillum lipoferum 显示文摘DENISE M S BUFF K CLAUSEN E 1996Chemosphere1996,33,8:1
14Twenty- five years of corporate gover- nancere search and counting 显示文摘Denis Diane K 2001Review of Financial E- conomics2001,,10:1
15Use of angiotensin Ⅱ inhibitors in patients that develop encapsuiating peritoneal sclerosis显示文摘Denise E S Inna K Mario R K 2010Peritoneal Dialysis International2010,6,30:1
16Leverage and investment in diversified firms显示文摘Seoungpil A Denis D J Diane K D 0,,:1
17Acute thoracolumbar burst fractures in the absence of neurologic deficit a comparison between operative and nonoperative treatment显示文摘Denis F Armstrong GWD Searls K 0,,:1
18Influence of lead acetate on glutathione and its related enzymes in different regions of rat brain显示文摘Bokara K K Blaylock I Denise S B 2009Appl Toxicol2009,29,:1
19HIV voluntarycounseling and testing and behavioral risk redection in developingcountries : a meta-analysis : 1990~2005显示文摘Denision J A 0’ Reilly K R Schmid G P 2008AIDS Behav2008,12,3:1
20Toward a theory of organizational culture and effectiveness 显示文摘DENISION D R MISHRA A K 1995Organization Science1995,6,2:1
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