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| 1 | Ilizarov bone transport combined with the Masquelet technique for bone defects of various etiologies (preliminary results)显示文摘BACKGROUND The Ilizarov bone transport(IBT)and the Masquelet induced membrane technique(IMT)have specific merits and shortcomings,but numerous studies have shown their efficacy in the management of extensive long-bone defects of various etiologies,including congenital deficiencies.Combining their strong benefits seems a promising strategy to enhance bone regeneration and reduce the risk of refractures in the management of post-traumatic and congenital defects and nonunion that failed to respond to other treatments.AIM To combine IBT and IMT for the management of severe tibial defects and pseudarthrosis,and present preliminary results of this technological solution.METHODS Seven adults with post-traumatic tibial defects(subgroup A)and nine children(subgroup B)with congenital pseudarthrosis of the tibia(CPT)were treated with the combination of IMT and IBT after the failure of previous treatments.The mean number of previous surgeries was 2.0±0.2 in subgroup A and 3.3±0.7 in subgroup B.Step 1 included Ilizarov frame placement and spacer introduction into the defect to generate the induced membrane which remained in the interfragmental gap after spacer removal.Step 2 was an osteotomy and bone transport of the fragment through the tunnel in the induced membrane,its compression and docking for consolidation without grafting.The outcomes were retrospectively studied after a mean follow-up of 20.8±2.7 mo in subgroup A and 25.3±2.3 mo in subgroup B.RESULTS The“true defect”after resection was 13.3±1.7%in subgroup A and 31.0±3.0%in subgroup B relative to the contralateral limb.Upon completion of treatment,defects were filled by 75.4±10.6%and 34.6±4.2%,respectively.Total duration of external fixation was 397±9.2 and 270.1±16.3 d,including spacer retention time of 42.4±4.5 and 55.8±6.6 d,in subgroups A and B,respectively.Bone infection was not observed.Postoperative complications were several cases of pin-tract infection and regenerate deformity in both subgroups.Ischemic regeneration was observed in two cases of subgroup B.Complications were corrected during the course of treatment.Bone union was achieved in all patients of subgroup A and in seven patients of subgroup B.One non-united CPT case was further treated with the Ilizarov compression method only and achieved union.After a follow-up period of two to three years,refractures occurred in four cases of united CPT.CONCLUSION The combination of IMT and IBT provides good outcomes in post-traumatic tibial defects after previous treatment failure but external fixation is longer due to spacer retention.Refractures may occur in severe CPT. | Dmitry Y Borzunov Sergey N Kolchin Denis S Mokhovikov Tatiana A Malkova | 2022 | World Journal of Orthopedics2022,13,3: | 6 |
| 2 | Metal influence on metallothionein synthesis in the hydrothermal vent mussel Ba thymodiolus thermophilus 显示文摘 | Hardivillier Y Denis F Demattei M V | 2006 | Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology2006,143,3: | 1 |
| 3 | Wavelet transform domain filters:a spatially selective noise filtration technique 显示文摘 | Xu Y S John B W Denis M H | 1994 | Trans on Image Processing1994,3,6: | 1 |
| 4 | Metabolic counterpart of de- creased apparent diffusion coefficient during hyperacute ischemic stroke: a brain proton magnetic resonance spectroscopic imaging study 显示文摘 | Nicoli F Lefur Y Denis B | 2003 | Stroke2003,34,: | 1 |
| 5 | Inhibition of preretinl and optic nerve head neovascularization in pigs by intravitreal triamcinalone acetonide显示文摘 | Denis RP Bingaman DP Yang Y Ladd B | 1996 | Ophthalmology1996,103,: | 1 |
| 6 | Atmospheric gaseous elemental mercury in downtown Toronto显示文摘 | DENIS M S SONG X J LU J Y | 2006 | Atmospheric Environment2006,40,: | 1 |
| 7 | Impurities in LiFePO4 and their Influence on material characteristics 显示文摘 | Denis Y W Donoue K Kadohata T | 2008 | J Electrochem Soc2008,155,7: | 1 |
| 8 | What Determines the Scope of the Firm over time? A Focus on Institutional Relatedness显示文摘 | PENG M W SEUNG H L DENIS Y L W | 2003 | Academy of Management Review2003,7,: | 1 |
| 9 | Isolation, identification, and partial cDNA clong of genomic RNA of jaagsiekte retrovirus, the etiological agent of sheep pulmonary adenomatosis 显示文摘 | Denis F Y Robert V Daniel W V | 1991 | J Virol1991,65,: | 1 |
| 10 | An Institution-Based View of International Business Strategy:A Focus on Emerging Economies显示文摘 | MIKE W P DENIS Y L WANG YI JIANG | 2008 | Journal of International Business Studies2008,39,: | 1 |
| 11 | Individual swift trust and knowledge-based trust in face-to-face and virtual team members 显示文摘 | Robert L Denis A Hung Y | 2009 | Journal of Management Information Systems2009,26,2: | 1 |
| 12 | Metabolic Counterpart of Decreased Apparent Diffusion Coefficient during Hyperacute Ischemic Stroke:a Brain proton Magnetic Resonance Spectroscopic Imaging Study显示文摘 | Nicoli F Lefur Y Denis B | 2003 | Stroke2003,34,1: | 1 |
| 13 | Metabolic counterpart of decreased apparent diffusion coefficient during hyperacute ischemic stroke:a brain proton magnetic resonance spect roscopicimaging study显示文摘 | Nicoli F Lefur Y Denis B | 2003 | Stroke2003,34,1: | 1 |
| 14 | Gene expression in giant-celltumors显示文摘 | Keith M S Edward Y C Denis R C | 2004 | J Biotechno2004,114,1: | 1 |
| 15 | Structure and composition of the aragonitic crossed lamellar layers in six species of Bivalvia and Gastropoda显示文摘 | Dauphin Y Denis A | 2000 | Comparative Biochemistry and Physiology Part A2000,126,: | 1 |
| 16 | Coverage, diversity, and functionality of a high-latitude coral community ( Tatsukushi, Shikoku Island, Japan) 显示文摘 | DENIS V MEZAKI T TANAKA K TANAKA K KUO C Y PALMAS S T KESHAVMURTHY S CHEN C S | 2013 | PlosOne2013,8,1: | 1 |
| 17 | Lower limb ischemia-reperfusion injury triggers a systemic inflammatory response and multiple organ dysfunction显示文摘 | Magdi M I Y Denis W H Aires A B | 2002 | World J Surg2002,26,: | 1 |
| 18 | Structure and composition of the aragonitic crossed lamellar layers in six species of Bivalvia and Gastropoda显示文摘 | DAUPHIN Y DENIS A | 2000 | Comparative Biochemistry and Physiology Part A2000,126,: | 1 |
| 19 | Wavelet transform domain filters:a spatially selective noise filtration technique显示文摘 | Xu Y S John B W Denis M H | 1994 | Trans on Image Processing1994,3,6: | 1 |
| 20 | The Yield Strength of Thin Copper Films on Kapton显示文摘 | Denis Y W Spaepen F | | 0,,: | 1 |