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| 1 | Phage therapy: An alternative to antibiotics in the age of multi-drug resistance显示文摘The practice of phage therapy, which uses bacterial viruses(phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice. Conventionally, phage therapy relies on the use of naturally-occurring phages to infect and lyse bacteria at the site of infection. Biotechnological advances have further expanded the repertoire of potential phage therapeutics to include novel strategies using bioengineered phages and purified phage lytic proteins. Current research on the use of phages and their lytic proteins against multidrug-resistant bacterial infections, suggests phage therapy has the potential to be used as either an alternative or a supplement to antibiotic treatments. Antibacterial therapies, whether phage-or antibiotic-based, each have relative advantages and disadvantages; accordingly, many considerations must be taken into account when designing novel therapeutic approaches for preventing and treating bacterial infection. Although much about phages and human health is still being discovered, the time to take phage therapy serious again seems to be rapidly approaching. | Derek M Lin Britt Koskella Henry C Lin | 2017 | World Journal of Gastrointestinal Pharmacology and Therapeutics2017，8，3： | 20 |
| 2 | Safety and feasibility of motexafin gadolinium administration with whole brain radiation therapy and ster- eotactic radiosurgery boost in the treatment of 6 brain metastases: a multi - institutional phase II trim 显示文摘 | Derek R M Pierre C Anne D | 2011 | Journal of Neuro -Oncology2011，105，2： | 1 |
| 3 | Maintai- ning the male germline: regulation of spermatogonial stem cells 显示文摘 | KYLE C JOHNATHAN B DEREK M | 2010 | J Endocrinology2010，205，： | 1 |
| 4 | Prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in three regions of England:a repeated cross-sectional study in primary care显示文摘 | LUIS N C ELIANA L M DEREK P | | 0，，09： | 1 |
| 5 | MICRO-CHECKER: software for identifying and correcting genotyping errors in microsatellite data 显示文摘 | VAN OOSTERHOUT C HUTCHINSON W F DEREK P M | 2004 | Molecular Ecology Notes2004，4，： | 1 |
| 6 | SAW parameters on Y-cut langasite structured materials显示文摘 | DEREK P DONALD M C NANCY S | 2007 | IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control2007，54，： | 1 |
| 7 | Determination of As,Cd,Pb,and Hg in urine using inductively coupled plasma mass spectrometry with the direct injection high efficiency nebulizer显示文摘 | MICHAEL G M DEREK C M PATRICK J P | | 0，，： | 1 |
| 8 | BaTiO3-based ceramics for tunable microwave applications显示文摘 | Antonio Feteira Derek C Sinclair Ian M Reaney | 2004 | J Am Ceram Soc2004，2004，： | 1 |
| 9 | Ozonation of carbamazepine in drinking water: identification and kinetic study of major oxidation products显示文摘 | DEREK M C HUBER M M WAGNER M | 2005 | Environmental Science & Technology2005，39，20： | 1 |
| 10 | Spatial trends and historical deposition of polychlorinated biphenyls in Canadian midlatitude and Arctic lake sediments显示文摘 | Derek C G M Alex O Grift N P | 1996 | Environmental science and technology1996，30，12： | 1 |
| 11 | Identification and characterization of acidic Mammalian chitinase inhibitors显示文摘 | Cole Derek C Olland Andrea M | | 0，，16： | 1 |
| 12 | The Treatment Mechanism of an Interspinous ProcessImplant for Lumbar Neurogenic Intermittent Claudication显示文摘 | JOSHUA C SHARMILA M DEREK P | 2005 | Spine2005，30，： | 1 |
| 13 | Personal power sys- tem 显示文摘 | Derek Dunn-Rankin Leal E M Walther D C | 2005 | Prog Energy Combust Sci2005，31，： | 1 |
| 14 | Microalgae as a sustainable energy source for biodiesel production: A review显示文摘 | AITMAD A L YASIN N H M DEREK C J C | 2011 | Renewable and Sustainable Energy Reviews2011，15，1： | 1 |
| 15 | The treatment mechanism of an interspinous process implant for lumbar neurogenic intermittent elaudieation显示文摘 | Joshua C Sharmila M Derek P | 2005 | Spine2005，30，7： | 1 |
| 16 | Microalgae as a sustainable energy source for biodiesel production: A review显示文摘 | Ahmad A L Yasin N H M Derek C J C | 2011 | Renew Sust Energ2011，15，： | 1 |
| 17 | Microalgae as a sustainable energy source for biodiesel production:A review显示文摘 | Ahmad A L Yasin N H M Derek C J C | | 0，，： | 1 |
| 18 | Spatial trends and historical deposition of polychlorinated biphenyls in Canadian midlatitude and Arctic lake sediments 显示文摘 | DEREK C G M ALEX O GRIFT N P | 1996 | Environmental Science and Technology1996，30，12： | 1 |
| 19 | Oplimization of thau- matin extraction by aqueous two-phase system (ATPS) using re- sponse surface methodology (RSM)显示文摘 | AHMAD A L DEREK C J C ZULKALI M M D | 2008 | Separation amt Purification Technology2008，62，： | 1 |
| 20 | Microalgaeas a sustainable energy source for biodiesel production:areview显示文摘 | Ahmad A L Yasin M N Derek C J Lim J K | 2011 | Renewable and Sustainable Energy Reviews2011，15，1： | 1 |
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