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| 1 | Meta分析方法系统性分析腹腔镜疝修补术的选择——TEP与TAPP显示文摘腹股沟疝修补术是最常见的手术之一。一个好的疝修补术应该是操作简单、手术时间短、安全。手术结果必须是创伤小、疼痛轻以及复发率低口j。腹腔镜疝修补术和传统的开放式疝修补术(openherniarepair,OHR)相比,术后疼痛轻、对患者限制少。目前,在临床上使用最多的腹腔镜疝修补术方法分别是:经腹腔腹膜前疝修补(transabdominalpreperitoneal,TAPP)和完全腹膜外疝修补(totallyextraperitonealherniarepair,TEP)。本文运用随机对照法研究资料,分析TEP与TAPP孰优孰劣。 | Bracale U Melillo P Pignata G Di Salvo E Rovani M Merola G Pecchia L Surg Endosc 陈大伟 | 2013 | 中华疝和腹壁外科杂志(电子版)2013，7，4： | 15 |
| 2 | Chronic constipation in hemiplegic patients显示文摘AIM: To assess the prevalence of bowel dysfunction in hemiplegic patients, and its relationship with the site of neurological lesion, physical immobilization and pharmacotherapy. METHODS: Ninety consecutive hemiplegic patients and 81 consecutive orthopedic patients were investigated during physical motor rehabilitation in the same period, in the same center and on the same diet. All subjects were interviewed ≥ 3 mo after injury using a questionnaire inquiring about bowel habits before injury and at the time of the interview. Patients’ mobility was evaluated by the Adapted Patient Evaluation Conference System. Drugs considered for the analysis were nitrates, angiogenic converting enzyme (ACE) inhibitors, calcium antagonists, anticoagulants, antithrombotics, antidepressants, anti-epileptics. RESULTS: Mobility scores were similar in the two groups. De novo constipation (OR = 5.36) was a frequent outcome of the neurological accident. Hemiplegics showed an increased risk of straining at stool (OR: 4.33), reduced call to evacuate (OR: 4.13), sensation of incomplete evacuation (OR: 3.69), use of laxatives (OR: 3.75). Logistic regression model showed that constipation was significantly and independently associated with hemiplegia. A positive association was found between constipation and use of nitrates and antithrombotics in both groups. Constipation was not related to the site of brain injury. CONCLUSION: Chronic constipation is a possible outcome of cerebrovascular accidents occurring in 30% of neurologically stabilized hemiplegic patients. Its onset after a cerebrovascular accident appears to be independent from the injured brain hemisphere, and unrelated to physical inactivity. Pharmacological treatment with nitrates and antithrombotics may represent an independent risk factor for developing chronic constipation. | F Bracci D Badiali P Pezzotti G Scivoletto U Fuoco L Di Lucente A Petrelli E Corazziari | 2007 | World Journal of Gastroenterology2007，13，29： | 15 |
| 3 | ConservativeapproachinPeutz-JeghersSyndrome:Single-balloon enteroscopyandsmallbowelpolypectomy显示文摘AIM: To assess the usefulness of the balloon assisted enteroscopy in preventing surgical intervention in pa-tients with Peutz-Jeghers syndrome (PJS) having a small bowel large polyps. METHODS: Seven consecutive asymptomatic pts(age 15-38 years) with PJS have been collected; six under-went polypectomy using single balloon enteroscopy(Olympus SIF Q180) with antegrade approach using push and pull technique. SBE system consists of the SIF-Q180 enteroscope, an overtube balloon control unit(OBCU Olympus Balloon Control Unit) and a dispos-able silicone splinting tube with balloon(ST-SB1). All procedures were performed under general anesthesia. Previously all pts received wireless capsule endos-copy(WCE). Prophylactic polypectomy was reservedmainly in pts who had polyps > 15 mm in diameter. The balloon is inflated and deflated by a balloon control unit with a safety pressure setting range from-6.0 kPa to +5.4 kPa. Informed consent has been obtained from pts or parents for each procedure.RESULTS: Six pts underwent polypectomy of small bowel polyps; in 5 pts a large polyp > 15 mm(range 20-50 mm in diameter) was resected; in 1 patient with WCE negative, SBE was performed for previous surgi-cal resection of gastrointestinal stromal tumors. In 2 pts endoscopic clips were placed due to a polypectomy. No surgical complication have been reported. SBE with resection of small bowel large polyps in PJS pts was useful to avoid gastrointestinal bleeding and emergency laparotomy due to intestinal intussuscep-tions. No gastrointestinal tumors were found in sub-sequent enteroscopic surveillance in all seven pts. In order surveillance, all pts received WCE, upper en-doscopy, ileocolonoscopy every 2 years. No pts had extraintestinal malignant lesions. SBE was performed when WCE was positive for significant polyps(> 15 mm).CONCLUSION: The effective of prophylactic polyp-ectomy of small bowel large polyps(> 15 mm) could be the first line treatment for conservative approach in management of PJS patients. | Torroni F Romeo E Rea F De Angelis P Foschia F Faraci S Federici di Abriola G Contini AC Caldaro T Dall’Oglio L | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 7 |
| 4 | Alleviated mucosal and neuronal damage in a rat model of Crohn's disease显示文摘AIM:To establish a rat model suitable to investigate the repetitive relapsing inflammations(RRI)characteristic to Crohn’s disease.METHODS:Colitis was induced by 2,4,6-trinitrobenzenesulfonic acid(TNBS).RRI were mimicked by repeating administrations of TNBS.Tissue samples were taken from control,once,twice and three times treated rats from the inflamed and adjacent non-inflamed colonic segments at different timepoints during the acute intestinal inflammation.The means of the ulcerated area were measured to evaluate the macroscopic mu-cosal damage.The density of myenteric neurons was determined on whole mounts by Hu C/Hu D immunohistochemistry.Heme oxygenase-1(HO-1)expression was evaluated by molecular biological techniques.RESULTS:TNBS-treated rats displayed severe colitis,but the mortality was negligible,and an increase of body weight was characteristic throughout the experimental period.The widespread loss of myenteric neurons,and marked but transient HO-1 up-regulation were demonstrated after the first TNBS administration.After repeated doses the length of the recovery time and extent of the ulcerous colonic segments were markedly decreased,and the neuronal loss was on a smaller scale and was limited to the inflamed area.HO-1 m RNA level was notably greater than after a single dose and overexpression was sustained throughout the timepoints examined.Nevertheless,the HO-1protein up-regulation after the second TNBS treatment proved to be transient.Following the third treatment HO-1 protein expression could not be detected.CONCLUSION:Experimentally provoked RRI may exert a protective preconditioning effect against the mucosal and neuronal damage.The persistent up-regulation of HO-1 m RNA expression may correlate with this. | Petra Talapka Lajos István Nagy Alexandra Pál Marietta Zita Poles Anikó Berkó Mária Bagyánszki László Géza Puskás éva Fekete Nikolett Bódi | 2014 | World Journal of Gastroenterology2014，20，44： | 3 |
| 5 | Laparoscopic resection for hepatocellular carcinoma:a matched-pair comparative study显示文摘 | Tranchart H Di Giuro G Lainas P | 2010 | Surg Endosc2010，24，5： | 1 |
| 6 | Emerging roles of ehemokines in prostate eaneer 显示文摘 | Vindrieux DI Escobar P Lazennec G | 2009 | Endocr Relat Caneer2009，16，3： | 1 |
| 7 | Enzyme activity and stability control by amphiphilic self - organizing systems in aqueous solutions 显示文摘 | SAVELLI G SPRETI N DI PROFIO P | 2000 | Current Opinion in Colloid & Interface Science2000，5，： | 1 |
| 8 | New simple and rapid method for purification of mesenchy- mal stem cells from the human umbilical cord Wharton jelly显示文摘 | Montanucci P G Basta T Pescara I Pennoni F Di Giovanni and R Calafiore | 2011 | Tis- sue Eng Part A2011，，： | 1 |
| 9 | Diagnostic accuracy and interobserver agreement of quasistatic ultrasound elastography in the diagnosis of thyroid nodules显示文摘 | Cantisani V Lodise P Di Rocco G | 2014 | Ultraschall Med2014，23，： | 1 |
| 10 | Atmospheric urban pollution: applications of an artificial neural network (ANN) to the city of Perugia显示文摘 | P Viotti G Liuti P Di Genova | 2002 | Ecological Modelling2002，，1： | 1 |
| 11 | Exposure of platelet fibrinogen-binding sites by collagen,arschidonic acid and ADP:inhibition by a monoelonal antibody to the glycoproteinⅡb-Ⅲa complex显示文摘 | Thiagarajan P Perussia B | 1983 | Blood1983，61，： | 1 |
| 12 | A poly- morphism in the VKORC1 gene is associated with an interindivid- ual variability in the dose anticoagulant effect of warfarin 显示文摘 | D'ANDREA G D'AMBROSIO R L DI PEMA P | 2005 | Blood2005，1，5： | 1 |
| 13 | Overview of Fire Retardant Meehanisms显示文摘 | Camino G Cost L Luda Di Cortemiglia M P | 1991 | Polymer Degradation and Stability1991，33，2： | 1 |
| 14 | MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast canc-er显示文摘 | Di Leva G Gasparini P Piovan Cy | 2010 | J Natl Cancer Inst2010，102，10： | 1 |
| 15 | Ablation of atrial fibrillation utilizing robotic catheter navigation in comparison to manual navigation and ablation:single-center experience显示文摘 | Di Biase L Wang Y Horton R Gallinghouse G J Mohanty P Sanchez J | | 0，，： | 1 |
| 16 | Electroluminescence of silicon nanocrystals in MOS structures显示文摘 | Franzò G Irrera A Moreira E C Miritello M Iacona F Sanfilippo D Di Stefano G Fallica P G Priolo F | | 0，，： | 1 |
| 17 | Chemokines and chemokine receptors blockers as new drugs for the treatment of chronic obstructive pulmonary disease显示文摘 | Caramori G Di Stefano A Casolari P | 2013 | Curr Med Chem2013，20，35： | 1 |
| 18 | Effects of high-dose furosemide and small-volume hypertonic saline solution infusion in comparison with a high dose of furosenmide as bolus in refractory congestive heart failure:Long-term effects显示文摘 | Licata G Di Pasquale P Parrinello G | 2003 | Am Heart J2003，145，3： | 1 |
| 19 | Laparoscopic resection for hepatocellular carcinoma:a matched-pair comparative study 显示文摘 | Tranchart H Di Giuro G Lainas P | 2010 | Surg Endosc2010，24，5： | 1 |
| 20 | Long QT,alteration of calcium-phosphate product,prevalence of ventricular arrhythmias and sudden death in peritoneal dialysis patients:a Holter study显示文摘 | Di Loreto P Ronco C Vescovo G | 2012 | Italian J Med2012，6，2： | 1 |
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