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| 1 | mmunological functions of liver sinusoida endothelial cells显示文摘 | Percy A Knolle Dirk Wohlleber | 2016 | Cellular & Molecular Immunology2016，13，3： | 18 |
| 2 | Acute compartment syndrome of the thigh following hip replacement by anterior approach in a patient using oral anticoagulants显示文摘Acute compartment syndrome(ACS) of the thigh following primary total hip arthroplasty(THA) is a highly uncommon complication and has not yet been reported before with regards to the anterior approach through the anterior supine interval. We present a case of a 69-year-old male patient with a history of stroke, who developed ACS of the thigh after elective THA while using therapeutic low molecular weight heparin as bridging for regular oral anticoagulation. ACS pathogenesis, diagnostic tools, treatment and relevant literature are discussed. The patient's ACS was recognized in time and treated by operative decompression with fasciotomy of the anterior compartment. Follow-up did not show any neurological deficit or soft-tissue damage. | Dirk Pieter Hogerzeil Imraan Muradin Eline W Zwitser Joris A Jansen | 2017 | World Journal of Orthopedics2017，8，12： | 8 |
| 3 | Human small intestine is capable of restoring barrier function after short ischemic periods显示文摘AIM To assess intestinal barrier function during human intestinal ischemia and reperfusion(IR).METHODS In a human experimental model,6 cm of jejunum was selectively exposed to 30 min of ischemia(I) followed by 30 and 120 min of reperfusion(R). A sham procedure was also performed. Blood and tissue was sampled at all-time points. Functional barrier function was assessed using dual-sugar absorption tests with lactulose(L) and rhamnose(R). Plasma concentrations of citrulline,an amino acid described as marker for enterocyte function were measured as marker of metabolic enterocytes restoration. Damage to the epithelial lining was assessed by immunohistochemistry for tight junctions( TJs),by plasma marker for enterocytes damage(I-FABP) and analyzed by electron microscopy(EM) using lanthanum nitrate as an electrondense marker.RESULTS Plasma L/R ratio's were significantly increased after 30 min of ischemia(30 I) followed by 30 min of reperfusion(30 R) compared to control(0.75 ± 0.10 vs 0.20 ± 0.09,P < 0.05). At 120 min of reperfusion(120 R),ratio's normalized(0.17 ± 0.06) and were not significantly different from control. Plasma levels of I-FABP correlated with plasma L/R ratios measured at the same time points(correlation: 0.467,P < 0.01). TJs staining shows distortion of staining at 30 I. An intact lining of TJs was again observed at 30 I120 R. Electron microscopy analysis revealed disrupted TJs after 30 I with paracellular leakage of lanthanum nitrate,which restored after 30 I120 R. Furthermore,citrulline concentrations closely paralleled the histological perturbations during intestinal IR.CONCLUSION This study directly correlates histological data with intestinal permeability tests,revealing that the human gut has the ability of to withstand short episodes of ischemia,with morphological and functional recovery of the intestinal barrier within 120 min of reperfusion. | Dirk HSM Schellekens Inca HR Hundscheid Claire AJI Leenarts Joep Grootjans Kaatje Lenaerts Wim A Buurman Cornelis HC Dejong Joep PM Derikx | 2017 | World Journal of Gastroenterology2017，23，48： | 4 |
| 4 | Fulminant myocarditis in adults: a narrative review显示文摘Fulminant myocarditis(FM)is an uncommon syndrome characterized by sudden and severe hemodynamic compromise secondary to acute myocardial inflammation,often presenting as profound cardiogenic shock,life-threatening ventricular arrhythmias and/or electrical storm.FM may be refractory to conventional therapies and require mechanical circulatory support(MCS).The immune system has been recognized as playing a pivotal role in the pathophysiology of myocarditis,leading to an increased focus on immunosuppressive treatment strategies.Recent data have highlighted not only the fact that FM has significantly worse outcomes than non-FM,but that prognosis and management strategies of FM are heavily dependent on histological subtype,placing greater emphasis on the role of endomyocardial biopsy in diagnosis.The impact of subtype on severity and prognosis will likewise influence how aggressively the myocarditis is managed,including whether MCS is warranted.Many patients with refractory cardiogenic shock secondary to FM end up requiring MCS,with venoarterial extracorporeal membrane oxygenation demonstrating favorable survival rates,particularly when initiated prior to the development of multiorgan failure.Among the challenges facing the field are the need to more precisely identify immunopathophysiological pathways in order to develop targeted therapies,and the need to better optimize the timing and management of MCS to minimize complications and maximize outcomes. | Santiago Montero Darryl Abrams Enrico Ammirati Florent Huang Dirk WDonker Guillaume Hekimian Cosme García-García Antoni Bayes-Genis Alain Combes Matthieu Schmidt | 2022 | Journal of Geriatric Cardiology2022，19，2： | 3 |
| 5 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009，7，4： | 3 |
| 6 | 聚氨酯包被尿素对奶牛泌乳性能和血浆生化指标的影响显示文摘本试验旨在研究饲喂包被尿素对奶牛泌乳性能及血浆生化指标的影响。选用24头荷斯坦泌乳牛,随机分为3组,分别饲喂含有豆粕(豆粕组)、聚氨酯包被尿素(包被尿素组)、饲料级尿素(尿素组)的等氮饲粮,粗蛋白质水平为17%。结果表明,与尿素组相比,包被尿素组和豆粕组奶牛干物质采食量提高了12.8%和12.6%,差异显著(P=0.02);产乳量由32.48 kg/d提高到34.48和34.53 kg/d,差异不显著(P>0.05),乳蛋白质产量有增加的趋势(P=0.06)。尿素组奶牛乳蛋白质率显著低于其他2组(P=0.04),而乳尿素氮浓度显著高于其他2组(P=0.03)。与尿素组相比,包被尿素组和豆粕组奶牛血浆中尿素氮含量由18.7 mg/dL降低到16.7和16.4 mg/dL(P=0.05)。乳尿素氮含量和血浆尿素氮含量存在正相关(R2=0.85)。由此得出,聚氨酯包被尿素可以部分替代饲粮中的豆粕,而不会对奶牛的泌乳性能产生不利影响。 | 辛杭书 张永根 孟庆翔 DIRK E A 刘庆平 | 2010 | 动物营养学报2010，22，6： | 3 |
| 7 | 不同形式的氮源对活体外瘤胃氨氮释放和发酵参数的影响显示文摘选用普通尿素、两种包被缓释尿素(快速型和慢速型)、糊化淀粉尿素和大豆分离蛋白作为五种处理因子,采用单因子试验设计,利用活体外人工瘤胃产气法,研究不同形式的氮源对活体外瘤胃氨氮释放速度和发酵参数的影响。结果表明:在0~12 h发酵过程中,不同形式氮源显著影响活体外瘤胃氨氮释放规律,其中两种包被尿素的氨氮浓度在各时间点均低于其他处理组(P<0.05),除在4 h时,快速释放包被尿素的氨氮浓度显著高于慢速释放包被尿素外(P<0.001),其余时间点均无影响,并且与大豆分离蛋白组氨氮的释放趋势相似。不同形式的氮源对挥发酸中的戊酸摩尔比例却有明显的影响,其中大豆分离蛋白组具有最高的戊酸含量(1.34 mmol/100 mol总挥发性脂肪酸),包被尿素(慢速)组的戊酸含量最低(1.13 mmol/100mol总挥发性脂肪酸),其他处理组居中。试验结果表明:两种包被尿素明显降低了瘤胃氨氮释放,与大豆分离蛋白相似,而糊化淀粉尿素与普通尿素相似,除戊酸外,不同处理日粮对72 h产气量及其他发酵参数没有明显影响。 | 辛杭书 张永根 孟庆翔 Dirk E A 刘庆平 | 2011 | 中国饲料2011，，18： | 3 |
| 8 | Quality of life after laparoscopic and open colorectal surgery: A systematic review显示文摘This study was a systematic review of the available evidence on quality of life in patients after laparoscopic or open colorectal surgery. A systematic review was performed of all randomized clinical trials (RCTs) that compared laparoscopic with open colorectal surgery. Study selection, quality assessment and data extraction were carried out independently by two reviewers. Primary endpoint was quality of life after laparoscopic and open colorectal surgery, as assessed by validated questionnaires. The search resulted in nine RCTs that included 2263 patients. Shortand long-term results of these RCTs were described in 13 articles. Postoperative follow-up ranged from 2 d to 6.7 years. Due to clinical heterogeneity, no meta-analysis could be conducted. Four RCTs did not show any difference in quality of life between laparoscopic or open colorectal surgery. The remaining five studies reported a better quality of life in favor of the laparoscopic group on a few quality of life scales at time points ranging from 1 wk to 2 years after surgery. In conclusion, based on presently available high-level evidence, this systematic review showed no clinically relevant differences in postoperative quality of life between laparoscopic and open colorectal surgery. | Sanne AL Bartels Malaika S Vlug Dirk T Ubbink Willem A Bemelman | 2010 | World Journal of Gastroenterology2010，16，40： | 3 |
| 9 | Kontrastmittelsonografie bei B-Bild-morphologisch unklaren Leberraumforderungen – Diagnostische Treffsicherheit im klinischen Alltag (DEGUM-Multicenter – Studie)显示文摘 | D Strobel K Seitz W Blank A Schuler C Dietrich A Herbay M Friedrich-Rust G Kunze D Becker U Will W Kratzer F Albert C Pachmann K Dirks H Strunk C Greis T Bernatik | 2008 | Ultraschall in Med2008，，05： | 2 |
| 10 | Industrial ecology framework for achieving cleaner production in the mining and minerals industry 显示文摘 | Arun J B Dirk J A van Z | 2006 | Journal of Cleaner Production2006，，34： | 1 |
| 11 | Shallow sea-floor reflectance and water depth derived by unmixing multispectral imagery 显示文摘 | Dirks A | 1987 | Photogrammetric Engineering & Remote Sensing1987，59，2： | 1 |
| 12 | Carbon dioxide absorption during extraperitoneal and transperitoneal endoscopic hernioplasty显示文摘 | Eberhard S Thomas AC Dirk A | 2000 | Anesth Analg2000，9，1： | 1 |
| 13 | Adhesion enhancement in waterborne acrylic latex binders synthesized with phosphate methacrylate monomers 显示文摘 | INIGO G A DIRK M JOSE R L | 2008 | Progress in Organic Coatings2008，61，： | 1 |
| 14 | Dynamic electric behavior and open-cir- cuit-voltage modeling of LiFePO4-based lithium ion secondarybattefies显示文摘 | Michael A R Dirk U S | 2011 | J Power Sources2011，196，1： | 1 |
| 15 | Columnar microstructure in vapor-deposited thin films 显示文摘 | Dirks A G Leamy H J | 1977 | Thin Solid Films1977，47，3： | 1 |
| 16 | Expression of p57(KIP2)potently blocks the growht oh human astrocytomas and induce cell senscence显示文摘 | TSUGU A SAKAI K DIRKS P B | 2000 | Am J Pathol2000，157，3： | 1 |
| 17 | Apoptosis in skeletal muscle with ag- ing显示文摘 | Dirks A Leeuwenburgh C | 2002 | Am J Physiol-Reg I2002，282，2： | 1 |
| 18 | Crystallisation of amorphous rare-earth-ironand transition-metal-boron thin films 显示文摘 | Dirks A G Gijsbers J R M | 1979 | J Phys D: Appl Phys1979，12，： | 1 |
| 19 | Development of individual three-dimensional bone substitutes using 'selective laser melting' 显示文摘 | Dirk A H Tobias W Matthias W | 2003 | European Journal of Trauma2003，29，4： | 1 |
| 20 | Repairing Relationships within and between Organizations: Building a ConeePtual Foundation 显示文摘 | DIRKS K T LEWIEKI R J ZAHEERA A | 2009 | Academy of Management Review2009，34，1： | 1 |
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