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| 1 | Contributions of biofilm and suspended sludge to nitrogen transformation and nitrous oxide emission in hybrid sequencing batch system显示文摘Hybrid system combines the nature of suspended growth and attached growth has been widely applied to wastewater treatment.In this research, the contributions to N transformation and N2O emission by biofilm and suspended sludge in the hybrid sequencing-batch reactor for a simultaneous nitrification, denitrification and phosphorus removal process were investigated. For the hybrid system,nitrification occurred mostly in the suspended sludge, while the biofilm played the major role in denitrification. The interaction ofthe biofilm and the suspended sludge in the same reactor resulted in a better overall nitrogen removal performance with simultaneousnitrification and denitrification. However, N2O emission was the main end product of nitrogen removal for the hybrid system; whileit was N2 for the biofilm. The relative low N2O emissions from the pure biofilm and the pure suspended sludge corresponded to therelatively high nitrate at the end of the aeration period compared with the hybrid system. | Ingwei Wayne Lo Kwang Victor Lo Don S Mavinic Dean Shiskowski William Ramey | 2010 | Journal of Environmental Sciences2010，22，7： | 17 |
| 2 | 4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8^(+) T cell proliferation显示文摘4-1BB(CD137)is a strong enhancer of the proliferation of CD8^(+)T cells.Since these cells require increased production of energy and biomass to support their proliferation,we hypothesized that 4-1BB signaling activated glucose and fatty acid metabolism.We found that treatment with agonistic anti-4-1BB mAb promoted the proliferation of CD8^(+)T cells in vitro,increasing their size and granularity.Studies with a glycolysis inhibitor and a fatty acid oxidation inhibitor revealed that CD8^(+)T cell proliferation required both glucose and fatty acid metabolism.Anti-4-1BB treatment increased glucose transporter 1 expression and activated the liver kinase B1(LKB1)-AMP-activated protein kinase(AMPK)-acetyl-CoA carboxylase(ACC)signaling pathway,which may be responsible for activating the metabolism of glucose and fatty acids.We also examined whether blocking glucose or fatty acid metabolism affected cell cycle progression and the anti-apoptotic effect of 4-1BB signaling.The increase of anti-apoptotic factors and cyclins in response to anti-4-1BB treatment was completely prevented by treating CD8^(+)T cells with the fatty acid oxidation inhibitor,etomoxir,but not with the glycolysis inhibitor,2-deoxy-D-glucose.We conclude that anti-4-1BB treatment activates glucose and fatty acid metabolism thus supporting the increased demand for energy and biomass,and that fatty acid metabolism plays a crucial role in enhancing the cell cycle progression of anti-CD3-activated CD8^(+)T cells in vitro and the anti-apoptotic effects of 4-1BB signaling on these cells. | Beom K Choi Do Y Lee Don G Lee Young H Kim Seon-Hee Kim Ho S Oh Chungyong Han Byoung S Kwon | 2017 | Cellular & Molecular Immunology2017，14，9： | 6 |
| 3 | Creep cavitation and grain boundary structure in type 304 stainless steel 显示文摘 | DON J MAJUMDAR S | 1986 | Acta Metall1986，34，： | 1 |
| 4 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 5 | Validation of CT dose - reduction simulation显示文摘 | Massoumzadeh P Don S Hildeboh CF | 2009 | Med Phys2009，36，： | 1 |
| 6 | Creep cavitation and grain boundary structure in type 304 stainless steel显示文摘 | Don J Majumdar S | 1986 | Acta Metall Mater1986，34，： | 1 |
| 7 | The role of ultrasound examination in the first trimester and at 16 weeks’ gestation to predict fetal complications in monochorionic diamniotic twin pregnancies显示文摘 | Liesbeth Lewi Paul Lewi Anke Diemert Jacques Jani Leonardo Gucciardo Tim Van Mieghem Elisa Doné Eduardo Gratacós Agnes Huber Kurt Hecher Jan Deprest | 2008 | American Journal of Obstetrics and Gynecology2008，，5： | 1 |
| 8 | Saposin-like proteins from the intestine of the blood-feeding hookworm,Ancylostoma caninum显示文摘 | Don TA Oksov Y Lustigman S | 2007 | Parasitology2007，134，3： | 1 |
| 9 | The geography of parameter space: an investigation into spatial nonstationarity 显示文摘 | FOTHERINGHAM A S CHARLTON M E BRUNS- DON C | 1996 | International Journal of GIS1996，，10： | 1 |
| 10 | Cyclin G2 As- sociates with protein phosphatase 2A catalytic and regulatory B subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest 显示文摘 | Bennin D A Don A S A Brake T | 2002 | J Biol Chem2002，277，27： | 1 |
| 11 | Facet joint orientation in spondylolysis and isthmic spondylolisthesis显示文摘 | Don A S Robertson P A | 2008 | J Spinal Disord Tech2008，21，2： | 1 |
| 12 | Histone deacetylase 6 plays a roleas a distinct regulator of diverse celluar processes 显示文摘 | Li YX Don^iee S So Hee K | 2012 | FEBS Journal2012，280，3： | 1 |
| 13 | Will the wave finally break--A brief view of the adoption of electronic medical records in the United States显示文摘 | Eta S Berner E D Don E | | 0，，01： | 1 |
| 14 | 3D moment forms: their construction and application to object identification and positioning 显示文摘 | Lo C H Don H S | 1989 | IEEE Transactions on Pattern Analysis and Machine Intelligence (S0162- 8828)1989，11，10： | 1 |
| 15 | Thin-glomeru- lar-basement-membrane uephropathy: is it a benign cause of isolated hematuria? 显示文摘 | Gandhi S Kalantar-Zadeh K Don BR | 2002 | South Med J2002，95，7： | 1 |
| 16 | Dietary effects on brain fatty acid composition: the reversibility of n-3 fatty acid deficiency and turnover of docosahexaenoic acid in the brain,erythrocytes and plasma of rhesus monkeys 显示文摘 | William E C Martha N Don S L | 1990 | J Lip Res1990，31，： | 1 |
| 17 | Counterproductive Work Behavior (CWB) in Response to Job Stressors and Organizational Justice: Some Mediator and Moderator Tests for Autonomy and Emotions 显示文摘 | Fox S Spector P E Don M | 2001 | Journal of Vocational Behavior2001，59，3： | 1 |
| 18 | Counterproductive Work Behavior(CWB)In Response To Job Stressors And Organizational Justice:Some Mediator And Moderator Tests For Autonomy And Emotions 显示文摘 | Fox S and Speetor P E and Don M | 2001 | Joumal of Voca- tional Behavior2001，59，3： | 1 |
| 19 | Malignant syphilis (lues ma- ligna) and concurrent infection with HIV 显示文摘 | Don PC Rubinstein R Christie S | 1995 | Int J Dermatol1995，34，6： | 1 |
| 20 | Osmotic priming of some herbage grass seed using polyethylene glycol (PEG)显示文摘 | Adegbuyi E Cooper S R Don R | 1981 | Seed Science and Technology1981，9，3： | 1 |
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